Navigation Links
Stem cells train heart following heart attack
Date:11/27/2007

Following a heart attack, part of the heart tissue dies. It is still not possible to restore the scar tissue arising as a result of this. The majority of stem cell researchers attempt to make new heart muscle cells from stem cells. Liesbeth Winter of the Leiden University Medical Center, however, was able to prove the concept of using the embryonic potential of adult human cells to train the heart: this cell therapy ensured that less tissue died and that the remaining heart cells functioned better.

The PhD student used the 'Epicardium Derived Cell' or EPDC. This cell plays a crucial role during embryonic heart development: the embryonic EPDCs provide cells for the connective tissue skeleton of the heart and for the walls of the coronary arteries. EPDCs also play an important role in the formation of a thick, compact heart muscle wall. Without EPDCs, the heart muscle would remain very thin and the embryo would die.

Human cells stimulate mouse cells

Winter used adult human EPDCs that she extracted from the atrium of the heart. She transplanted these cells to a mouse heart that had suffered an infarction. The mice receiving these cells retained a better heart function than mice without these cells, both in the short term and in the longer term of several weeks. The human cells also ensured that less mouse cells died off. Two weeks following cell transplantation, the treated hearts contained more blood vessels, the heart muscle cells exhibited an increased activity of DNA damage repair, and the wall was thicker where the infarct had occurred. These results suggest that EPDCs have an almost instant stimulating effect on the surrounding heart tissue following transplantation.


'/>"/>

Contact: Liesbeth Winter
31-071-526-9338
Netherlands Organization for Scientific Research
Source:Eurekalert

0

GOOD

Page: 1

Related medicine news :

1. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
2. Brain cells work differently than previously thought
3. Embryonic Stem Cells Repair Human Heart
4. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
5. Circulating fats kill transplanted pancreas cells, study shows
6. Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells
7. Melanoma drug revs immune cells but cancer cells ignore it
8. Scientists explain how insulin secreting cells maintain their glucose sensitivity
9. Embryonic stem cells used to grow cartilage
10. Molecular probe paints cancer cells in living animals, Stanford researchers find
11. USC researcher identifies stem cells in tendons that regenerate tissue in animal model
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2010)... Researchers at the Ireland Cancer Center of University Hospitals ... may lead to a new standard of care for ... in the February issue of Clinical Cancer Research, ... chemotherapy medicine, Triapine, was well tolerated in combination with ... cervical cancer. This regimen provided both significant reduction in ...
(Date:2/9/2010)... 2010- The research group of Dr. Franois Robert, a ... (IRCM), in collaboration with the team of Dr. Daniel ... accomplished a technical breakthrough: they mapped all the fragile ... Saccharomyces cerevisiae . The method used by the researchers ... published online today in the scientific journal Nature ...
(Date:2/9/2010)... MINNEAPOLIS/ST.PAUL (February 8, 2010)- Consuming two or more soft ... cancer by nearly two-fold compared with individuals who did ... Cancer Epidemiology, Biomarkers & Prevention , a journal ... Although relatively rare, pancreatic cancer remains one of the ... diagnosed survive five years later. , Mark Pereira, Ph.D., ...
(Date:2/9/2010)... first results from a large-scale study of key ... that a high percentage of medicines circulating on ... may contribute to the growth of drug-resistant strains ... form of malaria. The findings, released today by ... a USAID-funded program implemented by the US Pharmacopeial ...
(Date:2/9/2010)... LearnSomething Inc., a leader in ... mass retailers, today announced that Phil Keough ... management consulting company, has joined LearnSomething,s senior management ... a select team with the mission to continue ... performance products and services for retailers, including vehicles ...
Breaking Medicine News(10 mins):Health News:Researchers map all the fragile sites of the yeast Saccharomyces cerevisiae's genome 2Health News:Researchers map all the fragile sites of the yeast Saccharomyces cerevisiae's genome 3Health News:Soft drinks may increase risk of pancreatic cancer 2Health News:One-third of antimalarial medicines sampled in 3 African nations found to be substandard 2Health News:One-third of antimalarial medicines sampled in 3 African nations found to be substandard 3Health News:LearnSomething Brings Phil Keough On Board to Spearhead Retail Products and Services 2Health News:LearnSomething Brings Phil Keough On Board to Spearhead Retail Products and Services 3
... May 13 The rate of childhood,obesity in ... in Florida,32.5 percent of children ages 10 to ... and widespread threat of the obesity epidemic for,children, ... Blue,Foundation for a Healthy Florida ( http://www.bluefoundationfl.com ), ...
... Book Features Tips and Tricks for Hungry Chicks Including ... Guilt-Free Recipes and Survival Guides, ... tasty ways to rethink fiber. Lillien,s new book HUNGRY GIRL:,Recipes ... Martin,s Press, $17.95, April 29, 2008) showcases recipes for,low-calorie versions ...
... professional competitions airing ... nationally on ESPN2 and ESPNU, COLUMBUS, Ga., May 13 ... title sponsor of the Aflac Outdoor Games.,The inaugural three-day event is ... Complex in Columbus, GA. Aflac Outdoor Games will,include a variety of ...
... prescriptions for $10 and Increases the Number of Women,s ... Health Medications Offered at a Discount, ... KR ) in-store pharmacies will expand their generic drug,program ... their health needs. The retailer is offering 90-day prescriptions for,only ...
... specific gene to increase expression of a key enzyme, ... and injuries that can lead to cancer, University of ... have suggested the beneficial properties of vitamin D, said ... Center who led the research. Our findings reflect what ...
... Ga. A University of Georgia study that is the ... molesters finds that many of them were themselves victims of ... April issue of the Journal of Interpersonal Violence, has the ... treatment for offenders and their young victims. , This ...
Other Medicine News:Health News:The Blue Foundation for a Healthy Florida Announces $8 Million Initiative to Address Childhood Obesity 2Health News:Hungry Girl and Fiber One(R) Team Up to Offer Delicious Ways to Get Your Fiber Fix 2Health News:Aflac Announces Title Sponsorship of Outdoor Games 2Health News:Aflac Announces Title Sponsorship of Outdoor Games 3Health News:Kroger and Its Family of Stores Expand Discounted Generic Drug Program 2Health News:Kroger and Its Family of Stores Expand Discounted Generic Drug Program 3Health News:Vitamin D protects cells from stress that can lead to cancer 2Health News:Study: Most female child molesters were victims of sexual abuse 2
(Date:2/8/2010)... Feb. 8 Transgenomic, Inc. ... has completed a preliminary study with a leading ... licensed COLD-PCR technology to detect colorectal tumor-associated KRAS ... These were detected in plasma samples in which ... by standard DNA analysis methodologies such as Sanger ...
(Date:2/8/2010)... Feb. 8 Sagent Pharmaceuticals, Inc., ... that it has received FDA approval of labetalol ... severe hypertension.  The product will be available in ... mL and 200 mg per 40 mL, multi-dose ... than 70 million Americans have hypertension, or high ...
(Date:2/8/2010)... Feb. 8 Connectyx Technologies ... an advertising contract with SkyMall Inc. SkyMall produces ... in major airlines seat pockets. SkyMall has an ... advertisement featuring the MedFlash ® Personal Health ... table of contents in the front section of ...
Breaking Medicine Technology:Transgenomic Demonstrates Very High Sensitivity Detection of Tumor-Associated KRAS Mutations in Matched Plasma Samples Using COLD-PCR 2Transgenomic Demonstrates Very High Sensitivity Detection of Tumor-Associated KRAS Mutations in Matched Plasma Samples Using COLD-PCR 3Transgenomic Demonstrates Very High Sensitivity Detection of Tumor-Associated KRAS Mutations in Matched Plasma Samples Using COLD-PCR 4Sagent Pharmaceuticals Announces FDA Approval of Labetalol Hydrochloride Injection, USP 2Sagent Pharmaceuticals Announces FDA Approval of Labetalol Hydrochloride Injection, USP 3Connectyx Announces MedFlash(R) Advertising Contract with SkyMall Inc. 2Connectyx Announces MedFlash(R) Advertising Contract with SkyMall Inc. 3The ALS Association Cares for Those Who Care the Most in New Campaign 60077 1The ALS Association Cares for Those Who Care the Most in New Campaign 60077 2The ALS Association Cares for Those Who Care the Most in New Campaign 60077 3The ALS Association Cares for Those Who Care the Most in New Campaign 60077 4The ALS Association Cares for Those Who Care the Most in New Campaign 60077 5The ALS Association Cares for Those Who Care the Most in New Campaign 60077 6CVS pharmacy Rewards Shoppers For Passing on Plastic Bags 60074 1CVS pharmacy Rewards Shoppers For Passing on Plastic Bags 60074 2CVS pharmacy Rewards Shoppers For Passing on Plastic Bags 60074 3Uruguay 231 for Prosperity in South America 3B Venezuela and Bolivia the Worst in the Region Finds Legatum Prosperity Index 60071 1Uruguay 231 for Prosperity in South America 3B Venezuela and Bolivia the Worst in the Region Finds Legatum Prosperity Index 60071 2Uruguay 231 for Prosperity in South America 3B Venezuela and Bolivia the Worst in the Region Finds Legatum Prosperity Index 60071 3Uruguay 231 for Prosperity in South America 3B Venezuela and Bolivia the Worst in the Region Finds Legatum Prosperity Index 60071 4Uruguay 231 for Prosperity in South America 3B Venezuela and Bolivia the Worst in the Region Finds Legatum Prosperity Index 60071 5Uruguay 231 for Prosperity in South America 3B Venezuela and Bolivia the Worst in the Region Finds Legatum Prosperity Index 60071 6
... fatty acid synthase,inhibitor (FASi) compounds, led by FAS031, ... line tested, in both orthotopic,and flank models: 4 ... two,ovarian; breast; and, colon. In many cases the ... in extensive preclinical studies to,be remarkably safe and ...
... that the U.S. Food and Drug Administration ... combination with cisplatin,and 5-fluorouracil for induction therapy ... head and neck (SCCHN) before patients undergo,chemoradiotherapy ... approval on the results of the phase ...
Other Medicine Technology:FASgen Announces Significant Milestone in Its Cancer Drug Development Program 2Taxotere(R) (docetaxel) Granted FDA Approval to Treat Locally Advanced Head and Neck Cancer Prior to Chemoradiotherapy and Surgery 2Taxotere(R) (docetaxel) Granted FDA Approval to Treat Locally Advanced Head and Neck Cancer Prior to Chemoradiotherapy and Surgery 3Taxotere(R) (docetaxel) Granted FDA Approval to Treat Locally Advanced Head and Neck Cancer Prior to Chemoradiotherapy and Surgery 4
... for the treatment of presbyopia, a condition that ... older patients. , Presbyopia results from the gradual ... the eye as a person ages, making the ... the eye has a harder time focusing on ...
... forceps was designed by Joseph Kurstin, MD of ... the LASIK flap. It features disc-shaped tips ... the flap. Dr. Kurstin uses two forceps ... to straighten any micro striae. This stretching ...
... Piece Collamer lens, model CQ2015, combines the ... design. This lens contains a Collamer optic ... no angulation. These loops offer flexibility comparable ... tensile strength, and superior "shape memory". The ...
... has developed and patented a new, smaller and ... tomography (SPECT) with twice the resolution of existing ... an executive chair, runs on 110 Volts AC ... room without remodeling. The device has no visible ...
Medicine Products: