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Stem cells show promise for treating infertility in cancer patients
Date:11/1/2012

A promising stem-cell-based approach for treating infertility has been successfully demonstrated in non-human primates, as reported in a study published by Cell Press in the November issue of the journal Cell Stem Cell. The preclinical study represents an important milestone for translating this strategy to the clinic, particularly for cancer survivors who have been rendered infertile by chemotherapy they received before reaching sexual maturity.

"This is the first study to demonstrate that transplanted spermatogonial stem cells can produce functional sperm in higher primates," says senior study author Kyle Orwig of the University of Pittsburgh and Magee-Womens Research Institute. "This is an important step toward human translation."

Cancer patients who undergo radiation therapy or chemotherapy often become infertile
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Contact: Elisabeth (Lisa) Lyons
elyons@cell.com
617-386-2121
Cell Press
Source:Eurekalert

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