Navigation Links
Stem cells in adult testes provide alternative to embryonic stem cells for organ regeneration
Date:9/19/2007

Rafii says. "Nevertheless, it appears that these unique specialized spermatogonial cells could be an easily obtained and manipulated source of stem cells with exactly the same capability to form new tissues that we see in embryonic stem cells."

SPCs lie within a specific area of the testes and their sole function is to generate the precursors to sperm. "Normally, the spermatogonial progenitor cell is committed to only that function, and they're remarkably efficient, keeping men fertile well into advanced age," notes the study's lead author, Dr. Marco Seandel, researcher at the Howard Hughes Medical Institute and researcher/medical oncology fellow at Memorial Sloan-Kettering Cancer Center in New York City. Dr. Seandel provided the first real breakthrough in this research, developing the first efficient means of growing large quantities of SPCs for experimental use in the lab.

"That really allowed us to go full steam ahead in examining the potential of these very interesting cells," explains Dr. Rafii.

In their experiments, the Weill Cornell team concocted the perfect in vitro biochemical environment for the SPCs. This included particular helper cell types and growth factors aimed at fostering SPCs development away from creating germ cells and towards what scientists called "multipotency" -- the ability to develop into many different cell types.

Along the way, the team also cleared another hurdle.

"One problem with working with SPCs is that they've been extremely difficult to identify. We discovered that, within the testicular environment, only SPCs express a particular marker called GPR125," Dr. Seandel says. "That's a quantum leap forward in terms of being able to harvest and work with these cells."

Left to "soak" in their specially designed cell culture conditions, SPCs eventually made the change the team was hoping for. They did not develop into germ cells but instead grew to become multi-potent adult spermat
'/>"/>

Contact: Jonathan Weil
jweil@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

1

GOOD

Page: 1 2 3 4

Related medicine news :

1. Blood Cells Capable of Regenerating Liver
2. White Cells Count Can Predict Heart Attack Death Risk
3. Action of nerve cells
4. Common Cold Found to Fight Cancer Cells
5. Integrin helps healing process in cells
6. Therapy for stopping the spread of cancer cells
7. Hydroxyurea derivatives kill colon cancer cells
8. Gene Therapy Destroys Pancreatic Cancer Cells
9. Creating brain cells from bone marrow
10. A Chinese herb kills cancer cells
11. Immune cells halt round in space
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... 2013 Palo Alto has taken yet another ... cities with its recent major long-term solar power commitment. ... solar electric power purchase agreements , which together will result ... solar photovoltaic electric power per year, which is the equivalent ... That’s enough power to supply all 65,000+ Palo Alto residents---and ...
(Date:6/18/2013)... Recent research has shown that cancer cells have a ... normal cells. Now, scientists at The University of Texas ... provide a new strategy to combat lung cancer. , ... journal PLOS ONE , UT Dallas researchers compared ... normal lung cells taken from the same patient. ...
(Date:6/18/2013)... (PRWEB) June 18, 2013 The July 2013 ... Cheater’s Guide to Getting Beach Ready,” offers a list of ... look their best in a bathing suit this summer. The ... skin firming , smoothing cellulite , and more. (go ... Ourian, Medical Director of Epione Beverly Hills, “though I would ...
(Date:6/18/2013)... FL (PRWEB) June 18, 2013 A ... by storm. The burgeoning aquaculture industry is redefining the ... one of the most acclaimed personal culinary chefs on ... clientele on benefits of sustainable seafood and the promising ... in abundance these days. Many consumers strive to fully ...
(Date:6/18/2013)... one of the most successful Facebook brands of all time ... article What We Can Learn From one of the ... brand Gollan refers to is the multi-national Coca Cola who, ... (and rising). , The brand featured at number ten ... The Facebook data tracking publication ranked the brand highly because ...
Breaking Medicine News(10 mins):Health News:Palo Alto Seals the Deal on Major Solar Electric Investments 2Health News:Palo Alto Seals the Deal on Major Solar Electric Investments 3Health News:UT Dallas study suggests new approach to fight lung cancer 2Health News:UT Dallas study suggests new approach to fight lung cancer 3Health News:Skin Care – Getting Your Body Beach Ready 2Health News:New $119 Million Industry Swimming Up the East Coast 2Health News:Casey Gollan Shows What We Can Learn From One of the Best Facebook Pages There Is 2Health News:Casey Gollan Shows What We Can Learn From One of the Best Facebook Pages There Is 3
... with increasingly hectic work, school and extracurricular schedules, the ... time between parents and children. University of Missouri human ... vital step in maintaining family relationships and health. ... Environmental Sciences, says that instead of watching TV or ...
... , TUESDAY, Oct. 11 (HealthDay News) -- Studies on the ... plagued by design problems, a new report issued by the ... evidence exists that this kind of therapy helps such patients ... to develop definitive guidelines for its use. With traumatic ...
... , TUESDAY, Oct. 11 (HealthDay News) -- A healthy diet ... effect of a gene associated with an increased risk of ... published in the current online edition of the journal ... gene variant and diet in more than 27,000 people of ...
... By Randy Dotinga HealthDay Reporter , TUESDAY, Oct. 11 ... supplements seem to reduce inflammation in the intestines -- a potential ... However, more study needs to be done, and the ... or start gobbling up more ginger at meal times. "If ...
... (Oct. 11, 2011) According to new research by ... in treating a variety of diseases may produce unintended ... RNAs Induce Retinal Degeneration via TLR3 and IRF3", appears ... Molecular Therapy, a publication of the Nature Publishing ...
... Center is exploring the ethical challenges that clinicians ... immigrants in the United States. The project is supported ... Rights Program. Most of the estimated 11 million ... and are ineligible for public insurance programs. They are ...
Cached Medicine News:Health News:Human development experts recommend tuning in to family, not devices 2Health News:Evidence Lacking That Cognitive Rehab Therapy Helps Brain-Injured Vets 2Health News:Evidence Lacking That Cognitive Rehab Therapy Helps Brain-Injured Vets 3Health News:Healthy Diet May Counteract Heart Disease Gene 2Health News:Ginger Supplements Might Ease Inflammation Linked to Colon Cancer 2Health News:Emerging pharmaceutical platform may pose risks to retinal health 2Health News:New project examines medical safety net for undocumented patients 2
(Date:6/18/2013)... -- Royal Philips (NYSE: PHG, AEX: PHIA) ... in Imaging Equipment in the 2013 Best in KLAS ... Best in KLAS and Best in Category awards for ... Computed Tomography (CT), Ingenia 1.5T and 3.0T Magnetic Resonance ... Best in KLAS Awards: Medical Imaging & Infrastructure are ...
(Date:6/18/2013)... June 18, 2013  Specialty Coating Systems ... in Parylene coating technologies: SCS microRESIST™ Antimicrobial ... of Parylene with antimicrobial properties to effectively ... components. (Logo: http://photos.prnewswire.com/prnh/20130618/DE33772LOGO ... increase and continue to pose a challenge ...
(Date:6/18/2013)... BURLINGTON, Mass. , June 18, 2013 Decision ... for pharmaceutical and healthcare issues, finds that, over the past ... ( France , Germany , ... and the United Kingdom ) have been ... most of their HIV patients, primarily to reduce costs. Additionally, ...
Breaking Medicine Technology:Philips Named 2013 Overall Performance Leader In Imaging Equipment By KLAS 2Specialty Coating Systems Announces New Antimicrobial Parylene Technology 2One in Four Surveyed EU5 Physicians Has Been Required to Change a Prescription for Some or Most of Their HIV Patients in the Past Twelve Months, Primarily to Reduce Costs 2One in Four Surveyed EU5 Physicians Has Been Required to Change a Prescription for Some or Most of Their HIV Patients in the Past Twelve Months, Primarily to Reduce Costs 3
... Extension, a global authority on nutrition, health, and wellness ... product featuring ChromaDex,s (CDXC.OB) pTeroPure pterostilbene, which is now ... retailers. Life Extension pTeroPure contains 50 mg ...  Pterostilbene has been shown to be superior ...
... 6, 2011 Alere Health, LLC announced today ... Quality Assurance (NCQA) Health Information Products Certification for ... Nurse24(SM) program − a 24/7 nurseline staffed by ... make smarter healthcare decisions by providing immediate clinical ...
Cached Medicine Technology:Life Extension® Launches New Product Containing ChromaDex's pTeroPure® Pterostilbene 2Life Extension® Launches New Product Containing ChromaDex's pTeroPure® Pterostilbene 3Alere Earns NCQA Health Information Products Certification for Health Information Line 2
... designed specifically for the Palm Organizers ... ward rounds. It is intended to ... consultations that are requested by the ... Ward round examinations and to record ...
... tracking and billing. This ... Handheld application, a complete ... CPT™ and ICD-9-CM codes ... Designed for any medical ...
In addition to the patient data OB-on-Call contains a comprehensive Medications list displaying related drugs by brand name, generic title, and usage description notes....
Archimedes is an innovative specialty calculator. Forget having to remember complicated formulas, just enter the values and out come the results....
Medicine Products: