Navigation Links
Stem cells give clues to understanding cancer and make breakthrough in childhood leukaemia
Date:2/13/2008

ack into the cell, we stop the growth of the cells in culture, and also in mouse models. This gene is acting as a tumour suppressor.

The hope is that further investigation of factors such as DNA methylation could lead to potential new treatments for cancer.

On the other hand, Professor Tariq Enver of the Weatherall Institute for Molecular Medicine at the University of Oxford presented findings of his research on acute lymphoblastic leukaemia (ALL), which has now been published in the journal Science[3].

Professor Enver, who is a EuroSTELLS collaborator and his co-workers, demonstrated for the first time the existence of cancer stem cells in ALL. The researchers compared the blood of three-year-old identical twins, one of whom has the disease while the other is healthy.

The researchers found that both twins had genetically abnormal blood cells pre-leukaemic stem cells that reside in the bone marrow. It appears that these cells can either lay dormant or can somehow be triggered to develop into full-blown leukaemia stem cells.

The researchers showed that these cells arise from an abnormal fusion of two genes during the mothers pregnancy. Professor Enver said, This research means that we can now test whether the treatment of acute lymphoblastic leukaemia in children can be correlated with either the disappearance or persistence of the leukaemia stem cell. Our next goal is to target both the pre-leukaemic stem cell and the cancer stem cell itself with new or existing drugs to cure leukaemia while avoiding the debilitating and often harmful side effects of current treatments.

EuroSTELLS is a EUROCORES programme, managed by the European Medical Research Councils (EMRC) at the European Science Foundation.


'/>"/>
Contact: Dr. Fiona Kernan
fkernan@esf.org
33-388-762-180
European Science Foundation
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
2. Brain cells work differently than previously thought
3. Embryonic Stem Cells Repair Human Heart
4. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
5. Circulating fats kill transplanted pancreas cells, study shows
6. Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells
7. Melanoma drug revs immune cells but cancer cells ignore it
8. Scientists explain how insulin secreting cells maintain their glucose sensitivity
9. Embryonic stem cells used to grow cartilage
10. Molecular probe paints cancer cells in living animals, Stanford researchers find
11. USC researcher identifies stem cells in tendons that regenerate tissue in animal model
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... Graphics, coding, typography and search engine optimization– ... of web design and require thorough knowledge to create ... to create a website can be as easy as ... reviews and Facebook posts all accumulate on a multiple ... evolution of how a business can develop a website," ...
(Date:10/30/2014)... 30, 2014 High efficacy and ... in the medical-grade skin care domain: Cosmederm, the ... uniquely potent topical dermatological products, today announces the ... ) with patented COSMEDERM®-7 anti-irritant technology. , ... (50% and 70%) and a low pH (pH ...
(Date:10/30/2014)... October 30, 2014 PreDiabetes Centers ... PreD Store shoppers with a supply of sugardown®, ... to reduce post-meal blood sugar spikes. Learning how to ... an important part of a diabetes prevention plan. , ... receive one complimentary tube of sugardown. The offer expires ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 Radio listeners ... raising questions about the impact of traditional radio commercials ... method most likely to influence a purchasing decision. , ... of 525 consumers conducted by radio marketing company CRN ... categories, isolating the results of respondents who indicated they ...
(Date:10/30/2014)... Tara Haelle HealthDay Reporter ... More than 100 genes have been identified that appear ... And researchers say they are on their way ... contribute to the disorder. Autism spectrum disorders include ... social difficulties and repetitive behaviors. An estimated one in ...
Breaking Medicine News(10 mins):Health News:Facebook Websites In Thirty-Seconds 2Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 2Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 3Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 4Health News:PreDiabetes Treatment Company Offers PreD Store Shoppers Supplements to Support Healthy Blood Sugar 2Health News:CRN Research On Radio Messaging Effectiveness Now Available In Four Specific Product Categories 2Health News:CRN Research On Radio Messaging Effectiveness Now Available In Four Specific Product Categories 3Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 2Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 3
... Study highlights:, - A blood test recently approved ... better than tests currently used in the,United States., ... mortality in these,patients, which should allow healthcare providers to ... NEW ORLEANS, Nov. 11 A new blood test,identifies ...
... NEW ORLEANS, Nov. 11 A veteran ... Association Howard L.,Lewis Achievement Award for excellence ... Stiles of Freemont, Calif., was honored for ... clinical, economic,political, ethical and cultural implications of ...
... BROOK, Ill., Nov. 11 Over $3.2 million ... days by members of the University,HealthSystem Consortium,s (UHC) ... tool. With the new, easy-to-use UHC,Interactive WorkPlan, materials ... the intuitive reports to identify, analyze, and act ...
... (NEWARK, N.J., Nov. 11, 2008) The F.M. Kirby Foundation ... of Nursing at Rutgers, The State University of New Jersey, ... New Jersey residents. , The grant will also fund the ... research and service in the best academic tradition, said Interim ...
... the treatment of erectile dysfunction and pulmonary hypertension ... of the type-5 phosphodiesterase. The type-5 phosphodiesterase is ... of sildenafil on splanchnic blood flow and portal ... led by Otto Clemmesen from Denmark addresses this ...
... Nov. 11 /PRNewswire-FirstCall/ - SXC Health Solutions Corp.,("SXC" ... SXC), a leading provider of,pharmacy benefits management services, ... the Yale Club in New York City on ... 8:00 a.m. until approximately,11:00 a.m. eastern time and ...
Cached Medicine News:Health News:New Blood Test Better Identifies Heart Failure Patients in ER 2Health News:New Blood Test Better Identifies Heart Failure Patients in ER 3Health News:New Blood Test Better Identifies Heart Failure Patients in ER 4Health News:SpendLINK(TM) Enhancements Help Academic Medical Centers Easily Track Savings Opportunities 2Health News:SXC Health Solutions to host analyst and institutional investor event 2
(Date:10/30/2014)... 2014 WuXi PharmaTech (Cayman) Inc. (NYSE: ... platform company serving the pharmaceutical, biotechnology, and medical device ... and the United States , today ... Tel Aviv area of Israel.  ... broad platform of integrated R&D services to local customers. ...
(Date:10/30/2014)... Boston Scientific Corporation (NYSE: BSX ... Suisse Annual Healthcare Conference on Tuesday, November 11, 2014 ... Brennan , executive vice president and chief financial officer, ... approximately 8:00 a.m. PT followed by a question and ... presentation and question and answer session will be available ...
(Date:10/30/2014)... , Oct. 30, 2014   ViaDerma, Inc. ... to bringing new products to market, has recently ... TetraStem. TetraStem is a topical liquid tetracycline-based antibiotic ... that can convert oral medication active ingredients into ... a first aid antibiotic to help prevent skin ...
Breaking Medicine Technology:WuXi AppTec Launches Representative Office in Israel, Forms Strategic Collaboration with Pontifax 2Boston Scientific To Participate In 2014 Credit Suisse Annual Healthcare Conference 2ViaDerma, Inc. Lead Product TetraStem Shown Effective in Fighting Staph Infections including MRSA 2ViaDerma, Inc. Lead Product TetraStem Shown Effective in Fighting Staph Infections including MRSA 3
... , FRAZER, Pa., ... announced that it has filed a lawsuit in U.S. District ... of U.S. Patent Nos. 7,132,570 (the ",570 Patent"), 7,297,346 (the ... product NUVIGIL® (armodafinil) Tablets [C-IV]. Cephalon has a three-year ...
... , NEW ... market research report is available in its catalogue: , ... , http://www.reportlinker.com/p0164248/Pharmaceutical-Contract-Manufacturing---Global-Market-Trends.html ... form of increasing competition in generic markets, rising cost ...
Cached Medicine Technology:Cephalon Files Patent Infringement Lawsuit Against Teva Pharmaceuticals 2Cephalon Files Patent Infringement Lawsuit Against Teva Pharmaceuticals 3Cephalon Files Patent Infringement Lawsuit Against Teva Pharmaceuticals 4Reportlinker Adds Pharmaceutical Contract Manufacturing - Global Market Trends 2Reportlinker Adds Pharmaceutical Contract Manufacturing - Global Market Trends 3Reportlinker Adds Pharmaceutical Contract Manufacturing - Global Market Trends 4Reportlinker Adds Pharmaceutical Contract Manufacturing - Global Market Trends 5
... is enzyme immunoassay kit for the ... concentration in serum. Enzyme immunoassay (EIA) ... many protein hormones in body fluids ... rapid and specific assay. This enzyme ...
SHIONORIA BNP,is a reagent used in the measurement of blood BNP. The blood BNP test allows accurate estimation of coronary functions....
... method for the semi-quantitative determination of ... human serum. The results of the ... an aid in the diagnosis of ... with elevated anti-neutrophil cytoplasmic antibodies (P-ANCA) ...
... The determination of Ang ... in monitoring the pharmacological effect ... variety of angiotensin converting enzyme ... II receptor antagonists as well ...
Medicine Products: