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Stem cells derived from adult testes produce wide range of tissue types
Date:9/19/2007

cell lines. None of these GPR125-positive germ cell lines was previously readily available for genetic, biochemical, and cellular analysis by other laboratories, says Rafii. We intend to share them with other researchers.

Rafiis lab is now investigating whether GPR125 can be used to isolate cells from other adult tissues that can be converted into multipotent stem cells. His group has also begun pursuing a similar effort in ovaries. Its much more difficult, he said. However, it is possible that reprogrammable stem cells with similar properties to GPR125-positive SPCs may also exist, although at very low numbers, in adult mouse or human ovaries. His lab is actively investigating this intriguing possibility, Rafii said.


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Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
Source:Eurekalert

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