Navigation Links
Stem cells derived from adult testes produce wide range of tissue types
Date:9/19/2007

ablished a highly sophisticated culture system in which the progenitor cells rapidly grow and divide, creating a large population of cells that can be converted into MASCs.

It appears that these specialized GPR125-positive spermatogonial cells could be an easily obtained and manipulated source of stem cells with a similar capability to form new tissues that we see in embryonic stem cells, said Rafii. For male patients, he believes, It could someday mean a readily available source of stem cells that gets around ethical issues linked to embryonic stem cells. It also avoids issues linked to tissue transplant rejection, since these autologous cells come from the patients own body.

Rafiis team is currently pursuing a similar study of human testes to determine whether stem cells derived from their spermatogonial progenitor cells share the pluripotency of the mouse MASCs. We believe this to be an easily obtainable goal in the near future, he said.

If they succeed, several steps remain before such stem cells could be applicable to humans. We still have to learn the exact biochemical and epigenetic switch that tells GPR125-positive SPCs to convert into MASCs, said Marco Seandel, a senior post-doctoral fellow in Rafiis laboratory who is the first author of the Nature paper. Discovering that switch will be crucial to our being able to create MASCs on demand,

There is a chance that implanted cells derived from MASCs may trigger cancer in the recipient. This is an area that requires further investigation, Rafii said. However, he noted, So far, we havent seen any cancer or evidence of pro-cancerous activity in adult mice that are implanted with differentiated MASC cell tissue derivatives.

Rafii and his team have worked out the growing conditions that coax spermatogonial progenitor cells to develop into MASC germ lines-- genetically stable stem cells that continue reproducing indefinitely. Stem cell studies have been limited to date by the scarcity of germ
'/>"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Blood Cells Capable of Regenerating Liver
2. White Cells Count Can Predict Heart Attack Death Risk
3. Action of nerve cells
4. Common Cold Found to Fight Cancer Cells
5. Integrin helps healing process in cells
6. Therapy for stopping the spread of cancer cells
7. Hydroxyurea derivatives kill colon cancer cells
8. Gene Therapy Destroys Pancreatic Cancer Cells
9. Creating brain cells from bone marrow
10. A Chinese herb kills cancer cells
11. Immune cells halt round in space
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... July 29, 2014 Outsourced coding ... tripling in the number of hospitals contracting for ... 2015 deadline, according to the recently published Black ... leaders, found in the reports “Top Ranked Clinical ... now outsource Clinical documentation audit, review and programming. ...
(Date:7/29/2014)... invested $3.4 million this year to support innovative ... chronic diseases that affect more than 233,000 Canadians. ... research projects across Canada. This diverse research will ... improve our understanding (and potential treatment) of symptoms ... quality of life. , Crohn,s and Colitis ...
(Date:7/29/2014)... CHI-California Healthcare Institute today unveiled a ... C (hep C) epidemic in the U.S., the rise ... reduce human suffering. The report examines key data to ... C, while highlighting the significance of breakthroughs that have ... is a nonprofit, public policy research organization, representing leading ...
(Date:7/29/2014)... Thompson HealthDay Reporter MONDAY, ... virus that continues to rage throughout West Africa poses little ... only spreads through physical touch, and it can,t be spread ... deputy director of the National Center for Emerging & Zoonotic ... Prevention, explained in a Monday afternoon news conference. Those ...
(Date:7/29/2014)... Ill. By studying the injuries and aptitudes of ... the war, scientists are tackling -- and beginning to ... , The researchers found that brain regions that contribute ... intelligence and to emotional intelligence. This finding bolsters the ... social context of one,s life. , The ...
Breaking Medicine News(10 mins):Health News:Clinical Documentation Improvement Heats Up as Half of US Hospitals Make 2015 Preparations for ICD-10, the Rest to Rely on Outsourcers, Black Book Survey Reveals 2Health News:Clinical Documentation Improvement Heats Up as Half of US Hospitals Make 2015 Preparations for ICD-10, the Rest to Rely on Outsourcers, Black Book Survey Reveals 3Health News:Prestigious Crohn's and Colitis Canada grants fund promising Canadian research 2Health News:CHI Releases Report Highlighting Public Impact of Hepatitis C, Opportunities for Action in US 2Health News:CHI Releases Report Highlighting Public Impact of Hepatitis C, Opportunities for Action in US 3Health News:CHI Releases Report Highlighting Public Impact of Hepatitis C, Opportunities for Action in US 4Health News:CDC Downplays Ebola's Threat to the United States 2Health News:CDC Downplays Ebola's Threat to the United States 3Health News:CDC Downplays Ebola's Threat to the United States 4Health News:Team studies the social origins of intelligence in the brain 2Health News:Team studies the social origins of intelligence in the brain 3
... Children,s Research Hospital and Washington University School of Medicine ... identify the genetic changes that give rise to some ... joined forces to decode the genomes of more than ... have contributed tumor samples for this historic effort. ...
... ... look, but do not touch. Mamabears.com, a Web site devoted to providing parents with products ... strangers “Your Germs Are Too Big For Me Please Don’t Touch.” 100 percent of sales ... ...
... ... Jose, provides discounted dental services to local veterans referred through the Palo Alto VA hospital ... San Jose, CA (PRWEB) ... discounted services to American veterans in need of dental care. American veterans who are referred ...
... attempts to get young women pregnant , MONDAY, Jan. 25 ... of teenage girls and young women who engage in physical ... control the women are using. , The study, which appears ... finds that women who experience both birth-control sabotage and violence ...
... 100 fewer calories per meal for their children, study ... When nutritional information is available on fast-food restaurant menus, ... their kids, new research finds. , Often spurred on ... nutrition information about their menu items. But whether this ...
... ... Up Program at three of their Premiere Clubs. , ... (PRWEB) January 25, 2010 -- Diet-to-Go, a national leader in nutritional ... and wellness solutions operating 20 health clubs in California., , , , ,Through this exciting ...
Cached Medicine News:Health News:St. Jude and Washington University team to unravel genetic basis of childhood cancers 2Health News:St. Jude and Washington University team to unravel genetic basis of childhood cancers 3Health News:Mamabears.com Launches Stroller Signs – Finally a Kind Way to Say Do Not Touch 2Health News:Mamabears.com Launches Stroller Signs – Finally a Kind Way to Say Do Not Touch 3Health News:Top San Jose Dentists at Zeidler Dental Group Work with Local VA 2Health News:Male Abusers Often Sabotage Birth Control With Partners 2Health News:Listing Calories on Fast-Food Menus Cuts Kids' Intake 2Health News:Listing Calories on Fast-Food Menus Cuts Kids' Intake 3Health News:Diet-to-Go and Club One Fitness Join Forces For New Wellness Initiative 2
(Date:7/29/2014)... CITY , July 29, 2014  The ... Grand American Hotel in Salt Lake City ... representing some of most respected healthcare organizations in the ... Catalyst , is an industry conference devoted to providing ... analytics,  an essential element of both accountable care initiatives ...
(Date:7/29/2014)... , July 29, 2014  Ambit Biosciences (Nasdaq: ... and development of drugs targeting unmet needs in oncology, ... second quarter operational results after closing of the NASDAQ ... A conference call hosted by Michael Martino ... management will take place on the same day at ...
(Date:7/29/2014)... TRIANGLE PARK, N.C. , July 29, 2014 ... on cloud-based drug design and development, announced today ... grant from the National Science Foundation Small Business ... valued at $150,000. Cloud Pharmaceuticals ... the development process by implementing new, innovative cloud ...
Breaking Medicine Technology:Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 2Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 3Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 4Health Catalyst Adds Keynote Speakers, New Sessions, and Expands Attendee Limit for Healthcare Analytics Summit 2014 5Ambit Biosciences To Announce Second Quarter 2014 Financial Results 2Cloud Pharmaceuticals Receives Phase I NSF SBIR Grant Valued at $150,000 2
... HARLEYSVILLE, Pa. and LUDWIGSHAFEN, Germany, Oct. 20, 2011 ... the development of future film coating systems using Kollicoat® ... Colorcon has developed a pre-formulated additive ... enables efficient preparation and application of this polymer in ...
... Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX ) today ... management to discuss third quarter 2011 financial results, as well ... 2011, at 5:00 p.m. Eastern Time (2:00 p.m. Pacific Time). ... will be released earlier that day. Interested parties ...
Cached Medicine Technology:Colorcon and BASF Announce Collaboration to Develop Film Coating Applications Using Kollicoat® Smartseal 30 D 2
... the finest surgical-quality loupes available ... standard for innovative optical design, combining ... optimum performance with maximum comfort, SheerVision ... medical professionals worldwide. Make both a ...
... Experience the finest surgical-quality loupes ... set the standard for innovative optical ... support. Delivering optimum performance with maximum ... choice for medical professionals worldwide. Make ...
... of award-winning flip-up dental loupes in the ... loupes feature extremely high resolution razor-sharp clarity, ... for anti-glare, anti-fog, and scratch resistance. ... stylish, yet comfortable design with wrap around ...
... & portable FireFly LED light offers superior ... the new FireFly LED you'll get powerful, ... whereever your practice demands. High center-beam brightness ... your procedures, while the rechargeable battery provides ...
Medicine Products: