Navigation Links
Stem cell treatment for brittle bones in the womb
Date:1/29/2008

The extraordinary results of an in utero stem cell treatment could lead to a new treatment for babies with brittle bones, as well as a range of other disabling conditions, according to a maternal-fetal medicine researcher, now based at The University of Queensland (UQ).

Action Medical Research has announced the outcomes of an Imperial College London study, conducted by a team led by Professor Nicholas Fisk, that could lead to a stem cell treatment for babies with brittle bones - before they are even born.

Professor Fisk, who now heads the new $66m UQ Centre for Clinical Research, said the work held potential for improving treatment of other disabling conditions such as muscular dystrophy and congenital brain diseases.

Brittle bone disease or Osteogenesis imperfecta (OI), as the inherited disease is known, affects babies whilst they are inside their mother's womb. This is because collagen, one of the main building blocks for bone, fails to develop properly. The disease is detected by DNA testing or ultrasound before birth and leads to weak bones and stunted growth.

The team, led by Professor Nicholas Fisk, transplanted specially manipulated stem cells into 14 day old mouse fetuses that had OI. These mice had a reduction in long bone fractures of two thirds, compared with an untreated group, by the time they were twelve weeks old. They also found that the bones of these mice were stronger, thicker and longer than those with the disease that had not received the transplants. These outstanding results published in the journal Blood suggest that, with further research, this treatment could be translated to human babies in pregnancies that are affected by OI.

Dr Yolande Harley of charity Action Medical Research, which funded the project, said:

Professor Fisk's work is a real breakthrough. It suggests that if stem cells could be successfully transplanted before a baby with OI is even born, it could me
'/>"/>

Contact: Marlene McKendry
communications@uq.edu.au
61-733-653-367
Research Australia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New treatment effective in counteracting cocaine-induced symptoms
2. New treatment boosts muscle function in myasthenia gravis
3. Broad-based group of physicians calls for improvement in stroke treatment
4. Cranberry Could Juice Up Ovarian Cancer Treatment
5. Non-medicinal treatment touted for pre-schoolers with ADHD
6. Nonmedicinal treatment touted for preschoolers with ADHD
7. U of M study: Early treatment can reverse heart damage
8. Biologic treatment for rheumatoid arthritis and the risk of cancer
9. New Treatment Explored for Cluster Headaches
10. Thailand: Partners Open Free AIDS Treatment Clinic in Renowned AIDS Temple in Lop Buri
11. 4-Star Gen. Barry Mccaffrey, Former U.S. Drug Czar, to Keynote Recovery Happens! Rally for Treatment: Wed., Sept. 5, 11 Am, State Capitol West Steps, Sacramento
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... December 19, 2014 B. E. Smith, ... healthcare providers, has been retained to lead a national ... Medical Center in Estes Park, Colo. The top executive ... has recently placed more than 900 healthcare executives into ... a 25-bed, not-for-profit critical access hospital and level IV ...
(Date:12/19/2014)... Hands On Mobile Spa, has announced they ... On Wheels has been transformed into a utopia for the ... seems to disappear. The Virtual Tour showcases the beauty of ... corporate events and more. , The Virtual Tour shows viewers ... is actually an overhauled Winnebago. Marla Kaplan-Pelle, Director states " ...
(Date:12/19/2014)... Slone Partners , a national recruitment firm ... and laboratory testing industries, has promoted Leslie Loveless ... announcement comes after a year of expansion by ... Boston and several new additions to the team. ... experience," said Adam Slone, Chief Executive Officer. “Diagnostics ...
(Date:12/19/2014)... 2014 The Hermitage Club at ... Southern Vermont’s Deerfield Valley, announced today that it has ... rock songs. , Three time Grammy Award Winner ... concert followed by a trail naming ceremony. Hermitage Club ... include: “I’m Alright” the theme song for the movie ...
(Date:12/19/2014)... HealthDay Reporter THURSDAY, Dec. 18, 2014 (HealthDay ... high levels of air pollution late in pregnancy may have ... Researchers found that of nearly 1,800 U.S. women who ... most air pollution during pregnancy were twice as likely to ... the third trimester, specifically, showed the strongest correlation to autism ...
Breaking Medicine News(10 mins):Health News:Estes Park Medical Center Retains B. E. Smith to Recruit New Chief Financial Officer 2Health News:Estes Park Medical Center Retains B. E. Smith to Recruit New Chief Financial Officer 3Health News:A Virtual Tour Of Hands On Mobile Massage Spa Is Now Available 2Health News:A Virtual Tour Of Hands On Mobile Massage Spa Is Now Available 3Health News:Slone Partners Promotes Leslie Loveless to Chief Operating Officer 2Health News:The Hermitage Club Officially Names Four Ski Trails after Iconic Rock Songs by Grammy Award Winner Kenny Loggins 2Health News:Smog Exposure During Pregnancy Linked to Autism Risk 2Health News:Smog Exposure During Pregnancy Linked to Autism Risk 3
... WASHINGTON, Feb. 1 The American Public,Health Association (APHA) ... of Congress voted on legislation that is,important to public ... of individual votes,and selecting key public health votes during ... In the Senate, 46 out of 100 senators voted ...
... the vital role wetlands play in society, they remain among ... and positive effects of healthy wetlands for humans, the theme ... 2 February, is Healthy Wetlands, Healthy People. , According to ... claims the lives of more than 3 million people every ...
... Clinton,Campaign today announced the endorsement of the American ... the nation,s 2.9 million,registered nurses., "Too many ... and this,country deserves a president that will make ... M. Patton, MSN, RN, CNOR. "Senator,Clinton has shown ...
... 1 The Beaumont Technology,Usability Center will begin ... Food and,Drug Administration,s study on tubing and catheter ... released a Sentinel Event Alert on the,potential dangers ... and one instance of permanent loss of function ...
... Corporation (Nasdaq: OSCI ) will release financial ... December 31, 2007 on,Wednesday, February 6, 2008 prior ... conference call will be held at 8:30 a.m. ... other members of Oscient,s,management team. The Company announced ...
... of Acne ... Treatment, ... MD and co-investigators Mikiko,Enokibori, MD, and Vic Narurkar, MD, conducted a ... of acne,ranging from mild and moderate inflammatory acne to severe nodular ...
Cached Medicine News:Health News:APHA Scores Members of Congress on Public Health Voting Record 2Health News:Connection between health of wetlands and humans in focus 2Health News:Connection between health of wetlands and humans in focus 3Health News:The American Nurses Association Endorses Senator Hillary Rodham Clinton (D-NY) 2Health News:FDA Renews its Contract with Beaumont Technology Usability Center for Leadership of Patient Safety Project 2Health News:Webcast Alert: Oscient Pharmaceuticals Announces Date for Release of Fourth Quarter Financial Results 2Health News:New Study Shows Isolaz Can Reduce Acne Up to 90 Percent 2Health News:New Study Shows Isolaz Can Reduce Acne Up to 90 Percent 3
(Date:12/19/2014)... Dec. 19, 2014  Monarch America Inc. (OTCQB: CANK) ... is pleased to provide this review of the Company,s ... 2015. "Over this past year, we achieved ... am extremely proud to say that Monarch America is ... it has ever been," stated Eric Hagen , ...
(Date:12/19/2014)... , Dec. 18, 2014  Sage Analytics ( ... of equipment for the testing of marijuana potency ... the new Luminary™ Profiler, the industry,s first product ... in a cost-effective, portable unit. Designed ... needs of the cannabis industry, the Luminary™ Profiler ...
(Date:12/19/2014)... WASHINGTON , Dec. 18, 2014 Since ... Road, the site now known as the leading online ... has seen explosive growth in its offering of drugs ... Citizens Alliance show the takedowns did succeed in lowering ... our last review of the markets in August. But ...
Breaking Medicine Technology:Monarch America Inc. CEO Reviews Recent Achievements and Provides Outlook for 2015 2Monarch America Inc. CEO Reviews Recent Achievements and Provides Outlook for 2015 3Sage Analytics Develops Breakthrough System for Potency Testing of Cannabis Products 2Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 2Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 3
... 16, 2011 Reportlinker.com announces that ... available in its catalogue: ... and Peptides ... analysis focuses on cancer drug development ...
... 16, 2011 Unilife Corporation (NASDAQ: UNIS ... pricing of its underwritten registered public offering of 8,250,000 shares ... per share. All of the shares in the offering are ... the Company also granted the underwriters a 30-day option to ...
Cached Medicine Technology:Triple Analysis: Leukemia, Cancer Vaccines and Peptides 2Triple Analysis: Leukemia, Cancer Vaccines and Peptides 3Triple Analysis: Leukemia, Cancer Vaccines and Peptides 4Triple Analysis: Leukemia, Cancer Vaccines and Peptides 5Unilife Corporation Announces Pricing of Offering of 8,250,000 Shares of Common Stock 2Unilife Corporation Announces Pricing of Offering of 8,250,000 Shares of Common Stock 3
... Bird and Cronin, Inc. ... of Patient Footwear, Orthopedic ... Care Products. Our products ... quality and available in ...
... Spica Splint provides effective long-term stabilization ... fit. Adjustable radial and palmar stays ... Gamekeper's thumb, de Quervain's, scaphoid and ... straps.,FormFit™ Splints offer superior fit and ...
Qualcare™ Thumb Spica...
... QuickCast® Cast-like splints Slip ... dryer, and QuickCast conforms to ... cools. Reheat to adjust and ... coated with a temperature-sensitive polymer ...
Medicine Products: