Navigation Links
Stem cell therapy grows new blood vessels
Date:4/6/2009

Research led by David Hess of the Robarts Research Institute at The University of Western Ontario has identified how to use selected stem cells from bone marrow to grow new blood vessels to treat diseases such as peripheral artery disease. It's one of the severe complications often faced by people who've had diabetes for a long time. Reduced blood flow (ischemia) in their limbs can lead to resting pain, trouble with wound healing and in severe cases, amputation. The research is published in Blood.

Hess drew human bone marrow and simultaneously isolated three different types of stem cells that co-ordinate together to form new blood vessels. These are called pro-angiogenic stem cells. They were purified to remove any inflammatory or contaminated cells, and then injected into the circulation of mice which had one of their leg arteries ligated and removed. The researchers showed how these stem cells have a natural ability to hone in on the area of ischemia to induce blood vessel repair and improve blood flow. Hess says this research is clinically-applicable because they studied the function of human stem cells in immune-deficient mice.

The preclinical data from Hess' research was used by a biopharmaceutical company, Aldagen (www.aldagen.com ) to receive FDA approval for a multi-center clinical trial now underway in Houston, Texas, involving 21 patients with end-stage peripheral artery disease.

"We can select the right stem cells from the patient's own bone marrow and put them back in the area of ischemia to allow these cells to coordinate the formation of new blood vessels." says Hess, a professor in physiology and pharmacology at Western's Schulich School of Medicine & Dentistry. "These principles could be applied not only to ischemic limbs, but to aid in the formation of new blood vessels in ischemic tissue anywhere in the body, for example after a stroke or heart attack."


'/>"/>

Contact: Kathy Wallis
kwallis3@uwo.ca
519-661-2111 x81136
University of Western Ontario
Source:Eurekalert

Page: 1

Related medicine news :

1. Milkshakes are medicine for anorexic teens in family-based outpatient therapy
2. Supervised exercise therapy can lead to improvements in COPD symptoms
3. Starting HIV Therapy Earlier Saves Lives
4. New HIV Drug May Help Those Resistant to Therapy
5. Some radiation therapy treatments can decrease fertility
6. Whoopi Goldberg Conquers Fear of Flying Courtesy of Sir Richard Branson and Thought Field Therapy
7. Stem Cell Biotherapy Sues Casey Nabavi, Co-Founder and Former President, for Conduct Resulting in Claims by SCB Patients Against Nabavi, Embezzling Money and Converting Other Assets Belonging to SCB and for Wrongfully Establishing Cellulogix Biosciences t
8. Occupational Therapy Practitioners Identify Early Signs Of Autism Spectrum Disorder, Help Families Participate In Daily Routines
9. Cardiums InnerCool Announces Journal of Neurotrauma Highlights Hypothermia Therapys Role in Post Cardiac Arrest, and Traumatic Brain and Spinal Cord Injury Patients
10. Boehringer Ingelheim Plans to Launch U.S. Registry to Assess the State of Anticoagulation Therapy for Stroke Prevention in Patients with Non-Valvular Atrial Fibrillation
11. Prostate Cancer Patients in US and Europe Receive Treatments Using Enhanced Seed Prostate Brachytherapy Software
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... ... August 04, 2015 , ... Members receiving care from a doctor ... at a cost that is nine percent lower -- than those members at traditional ... New Jersey’s patient-centered programs. , “The promise of patient-centered, or value-based, care to ...
(Date:8/4/2015)... ... 04, 2015 , ... Increasingly, patients are researching online to ... In an effort to share more and better information with these savvy and ... share patient satisfaction ratings and comments about its doctors and advanced practice providers. ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... examination now offered by the world renowned Beverly Hills facelift surgeon , ... through cosmetic surgery techniques helps individuals to achieve an outer appearance that meets ...
(Date:8/4/2015)... ... August 04, 2015 , ... Providigm, LLC, a ... facilities, today announced details of the Advanced level of their national accreditation for ... QAPI Accreditation program , introduced in 2013, is based on standards for ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... personal health record (PHR) product has achieved Office of the National Coordinator ... Certification from Drummond Group. HealthCenter delivers the highest quality personal health record ...
Breaking Medicine News(10 mins):Health News:Horizon BCBSNJ: 2014 Results Show Patient-Centered Care Continues to Deliver on Promise of Better Quality Care at a Lower Cost 2Health News:Horizon BCBSNJ: 2014 Results Show Patient-Centered Care Continues to Deliver on Promise of Better Quality Care at a Lower Cost 3Health News:UPMC 1st in Pa. to Share Provider Ratings 2Health News:UPMC 1st in Pa. to Share Provider Ratings 3Health News:Beverly Hills Surgeon, Dr. Paul Nassif, is Now Offering Personal Consultations with Full Examinations for Facial Plastic Surgeries 2Health News:Beverly Hills Surgeon, Dr. Paul Nassif, is Now Offering Personal Consultations with Full Examinations for Facial Plastic Surgeries 3Health News:Nursing Homes Achieving New Advanced Accreditation See Improved Measures of Quality, Better Occupancy Rates 2Health News:Nursing Homes Achieving New Advanced Accreditation See Improved Measures of Quality, Better Occupancy Rates 3Health News:MedicaSoft's HealthCenter Earns ONC-HIT Certification from Drummond Group 2Health News:MedicaSoft's HealthCenter Earns ONC-HIT Certification from Drummond Group 3
... News) -- The prevalence of psoriasis -- a chronic, inflammatory ... and obese kids, researchers have found. The Kaiser ... , also found that teens with psoriasis (regardless of their ... risk for heart disease. "This study suggests a ...
... 20 (HealthDay News) -- For the average listener, the ... speaker,s sexual orientation, a new study finds. "I,m not ... vowel," study lead author Erik C. Tracy, a cognitive psychologist ... the American Institute of Physics. "Other researchers have done various ...
... , FRIDAY, May 20 (HealthDay News) -- All ... to 11 years old, according to new guidelines from the ... with a family history of premature cardiovascular disease or elevated ... as early as age 2. "It,s important that people ...
... Dr. Jeffrey M. Trent, F.A.C.M.G., a nationally recognized ... has been appointed Foreign Trade Counselor of Luxembourg in ... and Research Director of the Translational Genomics Research Institute ... Grand Rapids, Michigan. Both non-profit biomedical research institutes study ...
... News) -- Though a new study suggests that a dietary ... develop preeclampsia, the jury is still out over whether it ... it yet. Preeclampsia is a pregnancy complication ... hypertension. It affects about 5 percent of first pregnancies. ...
... SESSION I / Monday, May 23 / 8 ... Acute Coronary Syndrome Patients in Real World Clinical Practice: Observations ... Bhandary D2, Stephenson JJ1, Gold A2, Fu AC1, Kern DM1, ... SESSION II / Tuesday, May 24 / 8 ...
Cached Medicine News:Health News:Study Sees Link Between Psoriasis, Obesity in Kids 2Health News:Straight or Gay? Vowels in Speech May Give it Away 2Health News:Experts Say Cholesterol Screenings Should Start in Childhood 2Health News:TGen/VARI president Dr. Jeffrey Trent appointed Foreign Trade Counselor by Luxembourg 2Health News:Study Suggests Supplement May Protect Against Preeclampsia 2Health News:HealthCore presents ISPOR poster sessions 2
(Date:8/4/2015)... BETHLEHEM, Pa. , Aug. 4, 2015 ... takes prescription medications, yet only half of consumers surveyed ... 18 percent have ever used use them, according to ... FamilyWize , a community service partnership focused on improving ... The online survey polled 1,000 men and ...
(Date:8/3/2015)... WEST JORDAN, Utah , Aug. 3, 2015  BC ... Solutions has acquired Ohio Valley Medical Systems, one of ... MRI systems.  The addition of Ohio Valley Medical Systems ... to now include Hitachi MRI.   "We ... Mark Alvarez , President and CEO of BC Technical. ...
(Date:8/3/2015)... Calif., Aug. 3, 2015 AcelRx Pharmaceuticals, Inc. ... on the development and commercialization of innovative therapies for ... update and reported financial results for the three and ... highlights include: , On July 23, 2015, the ... a positive opinion for Zalviso™ for the management of ...
Breaking Medicine Technology:New Study Finds Consumers are Leaving Money at the Pharmacy 2New Study Finds Consumers are Leaving Money at the Pharmacy 3BC Technical Acquires Ohio Valley Medical Systems 2AcelRx Pharmaceuticals Provides Business Update and Reports Second Quarter and Six Months 2015 Financial Results 2AcelRx Pharmaceuticals Provides Business Update and Reports Second Quarter and Six Months 2015 Financial Results 3AcelRx Pharmaceuticals Provides Business Update and Reports Second Quarter and Six Months 2015 Financial Results 4AcelRx Pharmaceuticals Provides Business Update and Reports Second Quarter and Six Months 2015 Financial Results 5AcelRx Pharmaceuticals Provides Business Update and Reports Second Quarter and Six Months 2015 Financial Results 6AcelRx Pharmaceuticals Provides Business Update and Reports Second Quarter and Six Months 2015 Financial Results 7AcelRx Pharmaceuticals Provides Business Update and Reports Second Quarter and Six Months 2015 Financial Results 8AcelRx Pharmaceuticals Provides Business Update and Reports Second Quarter and Six Months 2015 Financial Results 9AcelRx Pharmaceuticals Provides Business Update and Reports Second Quarter and Six Months 2015 Financial Results 10
... American Association of,Health Freedom and the International ... the Baromedical Research,Institute and Louisiana State University ... successful treatment of chronic traumatic brain injury,(TBI). ... Oct 12;1174:120-9),are purportedly the first-ever demonstration of ...
... Oct. 10 Face,transplants, once on the fringe ... new estimates that suggest the risk of tissue,rejection ... a recent,review in Plastic and Reconstructive Surgery(R) (PRS), ... Plastic Surgeons (ASPS)., "We can only know ...
Cached Medicine Technology:Researchers Report First Successful Treatment of Chronic Traumatic Brain Injury 2Risks Associated With Face Transplants May Be Lower Than Previously Thought, ASPS Journal Review Suggests 2
... just about everything imaginable that might have to ... is designed for long term storage under archival ... over metal systems is overlooked, while the natural ... of desiccator and insulator, providing an environment that ...
A prepared Microscope Slide Cataloging and Storage System....
... Our moisture resistant, plastic covered ... high, each supporting up to 500 ... weight. Each box accommodates 2000 slides ... your varied storage requirements. Come unassembled ...
Shandon Plastic Slide Boxes...
Medicine Products: