Navigation Links
Stem cell advance a step forward for treatment of brain diseases
Date:12/7/2010

Scientists have created a way to isolate neural stem cells cells that give rise to all the cell types of the brain from human brain tissue with unprecedented precision, an important step toward developing new treatments for conditions of the nervous system, like Parkinson's and Huntington's diseases and spinal cord injury.

The work by a team of neuroscientists at the University of Rochester Medical Center was published in the Nov. 3 issue of the Journal of Neuroscience. Neurologist Steven Goldman, M.D., Ph.D., chair of the Department of Neurology, led the team.

The latest paper marks a six-year effort by Goldman's team to develop a better way to isolate pure preparations of neural stem cells directly from the human brain. These stem cells can renew themselves and have the potential to become a number of brain cell types for instance, oligodendrocytes that might help people with multiple sclerosis, or neurons to help people with Parkinson's disease. But after the first few months of human embryonic development, they become rare in the brain, and it's challenging for scientists to find, isolate and manipulate them. Yet those challenges must be met if stem cells are to live up to their promise as treatments for a host of human diseases of the nervous system.

So far, most efforts aimed at isolating human fetal stem cells have entailed cultivating brain tissue in tissue culture in the laboratory for months, then separating out the stem cells for study. In addition, today's techniques don't separate out just stem cells; typically, similar cells known as progenitor cells, which have already committed to becoming a certain type of cell, are also captured. The difference is crucial for scientists who often prefer to capture only uncommitted neural stem cells, whether to treat brain diseases requiring the replacement of multiple cell types or to better understand their function.

The Goldman lab's new technique snags only neu
'/>"/>

Contact: Tom Rickey
tom_rickey@urmc.rochester.edu
585-275-7954
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New therapies and gene target advance the treatment and understanding of hard-to-treat leukemias
2. Blood Cancer Advances May Improve Survival
3. ASHs 52nd Annual Meeting and Exposition showcases the latest advances in the field
4. Medical Advances Improving Lives, Surveyed Docs Say
5. Scientists announce new advance with potential for future cancer targeting
6. Combination therapy improves survival time for patients with advanced liver cancer
7. Hospital for Special Surgery scientists share advances in lupus and related conditions
8. UCI non-small cell lung cancer study highlights advances in targeted drug therapy
9. Early Humans More Advanced Than Thought
10. EMBO recognizes 63 researchers for advances in life sciences
11. Considerable proportion of patients with advanced cancer continue to undergo common cancer screening
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/3/2015)... (PRWEB) , ... August 03, 2015 , ... The art ... experience. Learning from her grandmother’s side at a young age, Nasreen Zereshki was extremely ... has decided to share her cookbook Recipes from My Persian Kitchen with the world. ...
(Date:8/3/2015)... , ... August 03, 2015 , ... ... National Forest, to Ahjumawi Lava Springs, California’s northernmost and among its least visited ... untapped ground water aquifers, whose main outflow is at Ahjumawi Lava Springs, part ...
(Date:8/3/2015)... ... ... From 2006-2017 the number of dental laboratories in the ... for the National Association of Dental Laboratories ( NADL ) by Valmont Research ... As the number of dental laboratories decreases, dentists will have fewer options when ...
(Date:8/3/2015)... ... , ... Constantin Vasilica, 48 from Romania wanted to have an alternative healing ... years of suffering and using medications with strong side effects. This had already forced ... time off or wait longer hours in the waiting rooms. Instead, he went home ...
(Date:8/3/2015)... ... August 03, 2015 , ... ... Code Council (ICC) announce an agreement to collaborate across a wide range ... to increasing building code knowledge among architects. , “Our combined membership, consisting of ...
Breaking Medicine News(10 mins):Health News:Persian Cuisine: Colorful and Extremely Healthy 2Health News:Medicine Lake Aquifer could ease California drought says fresh water advocate Sharon Kleyne – but is this necessary? 2Health News:Medicine Lake Aquifer could ease California drought says fresh water advocate Sharon Kleyne – but is this necessary? 3Health News:Medicine Lake Aquifer could ease California drought says fresh water advocate Sharon Kleyne – but is this necessary? 4Health News:Dental Association Announces Impending Reduction of Dental Laboratories Could Impact Dentists 2Health News:Dental Association Announces Impending Reduction of Dental Laboratories Could Impact Dentists 3Health News:Chinese Health Care Provider Heshoutang Now Give Patients Complimentary Online Healing Options 2Health News:Chinese Health Care Provider Heshoutang Now Give Patients Complimentary Online Healing Options 3Health News:Architects, International Code Council Ink Five-Year Collaborative Agreement 2Health News:Architects, International Code Council Ink Five-Year Collaborative Agreement 3
... suicidal thoughts as well, study finds , TUESDAY, June 9 ... bed at 10 p.m. are less apt to become depressed ... much later, recent research shows. , "This study bolsters the ... study author James Gangwisch, an assistant professor of psychiatry at ...
... LANCASTER, Pa., June 9 Herley Industries, Inc. (Nasdaq: ... Lancaster division received a contract award valued at approximately ... manufacture complex Integrated Microwave Assemblies (IMA) for an electronic ... Herley Chairman and CEO, Myron Levy, said, "Herley has ...
... professional pilots for example, depend on good vision as ... not required to undergo regular vision testing. A new ... they don,t recall ever having their vision tested or ... last vision exam. The study, performed at ...
... This release is available in French . ... antifungals are seeping into the waterways of North America, ... in the peer-reviewed journal Environmental Health Perspectives ... researchers, the review found that consumption of anti-infectives for ...
... unions, and veteran political leaders announces support for ... improve outcomes and reduce health care costs for ... support bipartisan reform agreement in Congress , ... an organization bringing together an expanding alliance of ...
... First Sugar-Free Functional Beverage Made Specifically for Kids, Over Soda ... WAT-AAH!, the first sugar-free functional beverage brand made specifically for ... their first nationwide WAT-AAH! Challenge to defy the expectation that ... over water. , , During the months of ...
Cached Medicine News:Health News:Early Bedtime May Help Stave Off Teen Depression 2Health News:Early Bedtime May Help Stave Off Teen Depression 3Health News:Herley Receives a $1.2 Million Contract Award for Complex Integrated Microwave Assemblies for U.S. Electronic Attack Aircraft 2Health News:Antibiotics, antimicrobials and antifungals in waterways 2Health News:Businesses, Unions, Veteran Party Leaders Unite Behind Bipartisan, Consensus Approach to Health Care Reform 2Health News:Businesses, Unions, Veteran Party Leaders Unite Behind Bipartisan, Consensus Approach to Health Care Reform 3Health News:Businesses, Unions, Veteran Party Leaders Unite Behind Bipartisan, Consensus Approach to Health Care Reform 4Health News:Businesses, Unions, Veteran Party Leaders Unite Behind Bipartisan, Consensus Approach to Health Care Reform 5Health News:Businesses, Unions, Veteran Party Leaders Unite Behind Bipartisan, Consensus Approach to Health Care Reform 6Health News:Businesses, Unions, Veteran Party Leaders Unite Behind Bipartisan, Consensus Approach to Health Care Reform 7Health News:Let Water Be Water, LLC Announces Results of the 'WAT-AAH! Challenge' 2
(Date:8/3/2015)... 3, 2015 Immune Pharmaceuticals, Inc. ("Immune") (NASDAQ: ... Daniel Teper , will present live at VirtualInvestorConferences.com on ... TIME:   11:30AM EDT LINK:    http://tinyurl.com/aug6-pre-imnp ... event where investors are invited to ask the company ... as well as the association,s "virtual trade booth." If ...
(Date:8/3/2015)... Shire plc (LSE: SHP, ... has acquired New York -based, ... With the acquisition, Shire acquires the global rights ... iodine (PVP-I) and 0.1% dexamethasone), a therapy in ... an ocular surface condition commonly referred to as ...
(Date:8/2/2015)... 2015  Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX ... 3 clinical trial met its primary endpoint, showing ... cancer patients with carcinoid syndrome that is not ... Telotristat etiprate was discovered using Lexicon,s gene science, ... company,s first discovery to complete a pivotal Phase ...
Breaking Medicine Technology:Immune Pharmaceuticals to Webcast Live at VirtualInvestorConferences.com August 6 2Shire Acquires Privately Held Foresight Biotherapeutics Inc., Boosting Ophthalmics Portfolio with Late-Stage Asset 2Shire Acquires Privately Held Foresight Biotherapeutics Inc., Boosting Ophthalmics Portfolio with Late-Stage Asset 3Shire Acquires Privately Held Foresight Biotherapeutics Inc., Boosting Ophthalmics Portfolio with Late-Stage Asset 4Shire Acquires Privately Held Foresight Biotherapeutics Inc., Boosting Ophthalmics Portfolio with Late-Stage Asset 5Shire Acquires Privately Held Foresight Biotherapeutics Inc., Boosting Ophthalmics Portfolio with Late-Stage Asset 6Lexicon Pharmaceuticals Reports Positive Top-Line Results For Pivotal Phase 3 Telotristat Etiprate Study In Cancer Patients With Carcinoid Syndrome 2Lexicon Pharmaceuticals Reports Positive Top-Line Results For Pivotal Phase 3 Telotristat Etiprate Study In Cancer Patients With Carcinoid Syndrome 3Lexicon Pharmaceuticals Reports Positive Top-Line Results For Pivotal Phase 3 Telotristat Etiprate Study In Cancer Patients With Carcinoid Syndrome 4Lexicon Pharmaceuticals Reports Positive Top-Line Results For Pivotal Phase 3 Telotristat Etiprate Study In Cancer Patients With Carcinoid Syndrome 5Lexicon Pharmaceuticals Reports Positive Top-Line Results For Pivotal Phase 3 Telotristat Etiprate Study In Cancer Patients With Carcinoid Syndrome 6
... NEW ORLEANS, June 6 Eli Lilly and Company (NYSE: ... study results of LY2189265, its investigational glucagon-like peptide 1 (GLP-1) ... diabetes. These data will be presented as part of the ... , , In the Phase II study, ...
... American Diabetes Association,s 69th Scientific Sessions shows investigational ... function tests , , NEW ORLEANS, June ... Powder is a well-tolerated, ultra rapid acting insulin ... usual antidiabetic treatment, according to data presented today ...
Cached Medicine Technology:Lilly Announces Positive Phase II Data on Investigational Medicine for Patients with Type 2 Diabetes 2Lilly Announces Positive Phase II Data on Investigational Medicine for Patients with Type 2 Diabetes 3Lilly Announces Positive Phase II Data on Investigational Medicine for Patients with Type 2 Diabetes 4AFRESA(R) Phase 3 Pulmonary Function Safety Data in Patients with Diabetes Presented at ADA 2AFRESA(R) Phase 3 Pulmonary Function Safety Data in Patients with Diabetes Presented at ADA 3
The technology in the LATITUDE system allows your doctor to get the same data from your device whether you are at home or in your doctor's office. This information transfer happens automatically....
Indicated to facilitate the intra-luminal placement of conventional guidewires beyond stenotic lesions, including chronic total coronary occlusions....
... Para 12 is a three-part differential control assayed ... STKR, J Series, T Series, AcT/AcT diff/AcT diff2, ... 1500, 1600, 1700, and 1800; Danam Datacell18, Datacell ... I-1800, I-1800MS/MS PLUS and I-1600; the ABX Micros ...
... Para 5X is a whole blood ... Pentra 60C+, 80 and 120, and the ... product offers a unique white cell differential, ... the algorithms on the systems. The product ...
Medicine Products: