Navigation Links
Stem Cells to Cartilage? Promising Results Seen in Mice
Date:10/29/2012

MONDAY, Oct. 29 (HealthDay News) -- Scientists who created cartilage from adult stem cells in mice say their success could lead to new treatments for cartilage injury and osteoarthritis.

The cartilage was created using induced pluripotent stem cells, which are adult cells that have been genetically altered to have the characteristics of embryonic stem cells. Induced pluripotent stem cells (iPSCs) have the potential to become different types of specialized cells.

"What this research shows in a mouse model is the ability to create an unlimited supply of stem cells that can turn into any type of tissue -- in this case cartilage, which has no ability to regenerate by itself," study senior author Farshid Guilak, a professor of orthopedic surgery at Duke University in Durham, N.C., said in a university news release.

The study was published online Oct. 29 in the journal Proceedings of the National Academy of Sciences.

Study leader Brian Diekman, a post-doctoral associate in orthopedic surgery, said the multi-step process used by the researchers shows "that iPSCs can be used to make high-quality cartilage, either for replacement tissue or as a way to study disease and potential treatments."

Guilak added that the advantage of this technique is "we can grow a continuous supply of cartilage in a dish." He said that in addition to cell-based therapies, this technology can also provide "patient-specific cell and tissue models that could be used to screen for drugs to treat osteoarthritis, which right now does not have a cure or an effective therapy to inhibit cartilage loss."

However, results achieved in animal trials do not necessarily apply to humans. The researchers said they next plan to use human induced pluripotent stem cells to test the cartilage-growing technique.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about osteoarthritis.

-- Robert Preidt

SOURCE: Duke University, news release, Oct. 29, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scientists decode software instructions of aggressive leukemia cells
2. New options for ease and accuracy in extraction of rare cells or separating blood
3. Stimulating brain cells with light
4. Research identifies protein that regulates key fate decision in cortical progenitor cells
5. UGA researchers boost efficacy of drugs by using nanoparticles to target powerhouse of cells
6. At the right place at the right time -- new insights into muscle stem cells
7. Lack of oxygen in cancer cells leads to growth and metastasis
8. Human Stem Cells Restore Hearing to Deaf Gerbils in Study
9. Gladstone scientists develop technique to decipher the dormant AIDS virus concealed in cells
10. University of Maryland study: Neonatal heart stem cells may help mend kids broken hearts
11. Researchers closer to understanding actions of cells involved in atherosclerosis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem Cells to Cartilage?  Promising Results Seen in Mice
(Date:6/28/2017)... (PRWEB) , ... June 28, 2017 , ... ... consulting firm servicing communities throughout the greater Cincinnati metropolitan area, is teaming up ... temporary lodgings for families with children receiving treatment in nearby hospitals. , Ronald ...
(Date:6/27/2017)... ... June 27, 2017 , ... DrugDev understands that for many ... trust the sponsor to pay them correctly and on time. As the search for ... strategies that encourage sites to work on their studies. , At a complimentary live ...
(Date:6/27/2017)... ... June 27, 2017 , ... The Congressional Budget Office (CBO) ... and replace the 2010 Patient Protection and Affordable Care Act (ACA), would result in ... be expected under current law. , More than 20 million Americans have gained health ...
(Date:6/27/2017)... (PRWEB) , ... June 27, 2017 , ... A January ... been projected to reach a staggering $6.81 billion by the year 2024 according to ... at a faster rate than those made from titanium. Los Angeles area clinic Beverly ...
(Date:6/27/2017)... , ... June 27, 2017 , ... ... to contribute to an upcoming case studies guidebook. This guidebook offers an excellent ... This book will include articles, case studies and how-to’s that fall into the ...
Breaking Medicine News(10 mins):
(Date:6/2/2017)... , June 2, 2017  NxStage Medical, Inc. (Nasdaq: ... care, today announced new findings demonstrating positive biochemical outcomes ... System One™. The data will be presented at ... Madrid, Spain . ... Improve Home Dialysis Network in Europe ...
(Date:5/30/2017)... 30, 2017 Hill-Rom Holdings, Inc. (NYSE: HRC), will ... Healthcare Conference on Tuesday, June 13, 2017, in ... Hill-Rom,s president and chief executive officer, is scheduled to present ... webcast can be accessed at http://ir.hill-rom.com/events.cfm . A recorded ... live event through September 13, 2017. ...
(Date:5/26/2017)... , May 26, 2017  Endo International plc (NASDAQ: ... , President and CEO, will represent the Company in a ... Healthcare Conference on Tuesday, June 13, 2017 at 10:40 a.m. ... at Terranea Resort in Rancho Palos Verdes, CA. ... for the event will be available on the Company,s website ...
Breaking Medicine Technology: