Navigation Links
Stem Cells to Cartilage? Promising Results Seen in Mice
Date:10/29/2012

MONDAY, Oct. 29 (HealthDay News) -- Scientists who created cartilage from adult stem cells in mice say their success could lead to new treatments for cartilage injury and osteoarthritis.

The cartilage was created using induced pluripotent stem cells, which are adult cells that have been genetically altered to have the characteristics of embryonic stem cells. Induced pluripotent stem cells (iPSCs) have the potential to become different types of specialized cells.

"What this research shows in a mouse model is the ability to create an unlimited supply of stem cells that can turn into any type of tissue -- in this case cartilage, which has no ability to regenerate by itself," study senior author Farshid Guilak, a professor of orthopedic surgery at Duke University in Durham, N.C., said in a university news release.

The study was published online Oct. 29 in the journal Proceedings of the National Academy of Sciences.

Study leader Brian Diekman, a post-doctoral associate in orthopedic surgery, said the multi-step process used by the researchers shows "that iPSCs can be used to make high-quality cartilage, either for replacement tissue or as a way to study disease and potential treatments."

Guilak added that the advantage of this technique is "we can grow a continuous supply of cartilage in a dish." He said that in addition to cell-based therapies, this technology can also provide "patient-specific cell and tissue models that could be used to screen for drugs to treat osteoarthritis, which right now does not have a cure or an effective therapy to inhibit cartilage loss."

However, results achieved in animal trials do not necessarily apply to humans. The researchers said they next plan to use human induced pluripotent stem cells to test the cartilage-growing technique.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about osteoarthritis.

-- Robert Preidt

SOURCE: Duke University, news release, Oct. 29, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Scientists decode software instructions of aggressive leukemia cells
2. New options for ease and accuracy in extraction of rare cells or separating blood
3. Stimulating brain cells with light
4. Research identifies protein that regulates key fate decision in cortical progenitor cells
5. UGA researchers boost efficacy of drugs by using nanoparticles to target powerhouse of cells
6. At the right place at the right time -- new insights into muscle stem cells
7. Lack of oxygen in cancer cells leads to growth and metastasis
8. Human Stem Cells Restore Hearing to Deaf Gerbils in Study
9. Gladstone scientists develop technique to decipher the dormant AIDS virus concealed in cells
10. University of Maryland study: Neonatal heart stem cells may help mend kids broken hearts
11. Researchers closer to understanding actions of cells involved in atherosclerosis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem Cells to Cartilage?  Promising Results Seen in Mice
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... Vida ... raised an $18M Series B led by Canvas Ventures . Other investors include ... to scale its mobile platform to serve more consumers who are managing chronic ...
(Date:12/8/2016)... ... December 08, 2016 , ... The ... offices headquartered in Jefferson County, is announcing the launch of a charity drive ... The number of homeless women and children in Birmingham has grown steadily since ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... The Compretta ... commercial and residential clients in and around the Hancock County area, is announcing the ... Hancock County Food Pantry. , The Hancock County Food Pantry has worked for more ...
(Date:12/7/2016)... PA (PRWEB) , ... December 07, 2016 , ... ... with the announcement that it is one of the early adopters completing EU-U.S. Privacy ... Framework is designed to provide companies on both sides of the Atlantic with a ...
(Date:12/7/2016)... ... December 07, 2016 , ... Kenall Manufacturing, a leader in ... MPCNGX . The MPCNGX is a multi-function, sealed, LED luminaire that meets the needs ... where and when it’s needed. , A 2’ x 4’ model features ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... , December 8, 2016 ... on the research, distribution, and marketing of pharmaceutical drug ... by patent protection and expiration. Additionally, these firms typically ... sector as a whole. Up for review this morning ... Synergy Pharmaceuticals Inc. (NASDAQ: SGYP ), Pernix ...
(Date:12/8/2016)... , Dec. 8, 2016 Spotlight ... advancing technologies designed to address rare, emerging and ... Chitra Edwin , Ph.D., RAC, as Senior Vice ... will provide leadership for all U.S. and international ... preparation of regulatory submissions, serving as the primary ...
(Date:12/7/2016)... "Lantus (Insulin Glargine) Biosimilar Clinical Trial & Opportunity Insight" report by PNS ... in clinical pipeline. Currently 5 biosimilar version of Lantus are commercially available ... Kenya , Czech Republic , ... , Slovakia , United Kingdom ... on Lantus expired in 2014. Lantus is the brand name for ...
Breaking Medicine Technology: