Navigation Links
Stem Cells Repair Stroke Damage in Rats
Date:2/20/2008

Study suggests same technique might one day work in humans

WEDNESDAY, Feb. 20 (HealthDay News) -- Human stem cells helped repair stroke-related brain damage in rats, Stanford University researchers report.

The use of neural cells derived from human embryonic stem cells led to improvements in the rats' physical abilities, according to the study, which is published in the Feb. 20 issue of Public Library of Science ONE. The stroke damage induced by the researchers left the rats with a weakened forelimb.

This is the first time that scientists have used human embryonic stem cells to generate neural cells that grow well in the lab, repair stroke damage in rats, and don't consistently form tumors after transplantation, according to the researchers.

While the findings show the potential of using stem cell therapies to treat stroke, the researchers noted this is a small study, and more research is needed to determine if this approach could work in humans.

In the laboratory, the researchers grew embryonic stem cells in a combination of growth hormones that prodded the cells to mature into stable neural stem cells. This was an important step, because immature cells tend to grow uncontrollably into tumors.

The neural stem cells were then transplanted into the brains of 10 rats with stroke-related brain damage. After two months, the transplanted neural stem cells had migrated to the damaged area of the brain and incorporated into the surrounding tissue. None of the transplanted cells formed tumors.

The rats that received the transplants were better able to use their forelimbs than rats that had similarly damaged brain regions but weren't given stem cell transplants.

Each year, about 780,000 people in the United States suffer strokes, according to the American Stroke Association.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about stroke.



-- Robert Preidt



SOURCE: Stanford University, news release, Feb. 19, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Human stem cells aid stroke recovery in rats
2. Tumor-killing virus selectively targets diseased brain cells
3. Gene therapy trains immune system to destroy brain cancer cells and reverses behavioral deficits
4. Transplanted Liver Lining Cells May Cure Hemophilia
5. Scientists Show Stem Cells Dont Cause Cancer
6. Overabundance of Immune Cells Might Trigger Lupus
7. How DDT metabolite disrupts breast cancer cells
8. Stem cells give clues to understanding cancer and make breakthrough in childhood leukaemia
9. A functional immune system can be derived from embryonic stem cells, preliminary study finds
10. Fluorescent Retinal Cells Warn of Eye Disease
11. UCLA stem cell scientists reprogram human skin cells into embryonic stem cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem Cells Repair Stroke Damage in Rats
(Date:8/16/2017)... Georgia (PRWEB) , ... August 16, 2017 , ... ... in Atlanta, opened their doors. They celebrate 30 years in business this year, ... create an up-to-date, inviting, tranquil space to serve their patients. , It ...
(Date:8/16/2017)... GA (PRWEB) , ... August 16, 2017 , ... ... for Telehealth, Inc. has received a three-year grant totaling $975,000, renewing its funding ... of Health and Human Services. , This funding marks, the fourth time the ...
(Date:8/16/2017)... ... August 16, 2017 , ... SGNA Standards of Infection ... reprocessing cycle, both between patient procedures and before storage, is a requisite practice ... important to the prevention of disease transmission and nosocomial infection as cleaning and ...
(Date:8/16/2017)... ... 16, 2017 , ... Connexion Point, a technology-enabled healthcare services company delivering outcome ... year. With 197% revenue growth over the past three years, Connexion Point ... , Previous honors include ranking 86th on the Inc. 500 in 2014, ...
(Date:8/16/2017)... ... August 16, 2017 , ... First Choice Emergency Room ... Dr. Douglas J. Harrison, as the new Medical Director of its Sienna Plantation facility. ... Medical Director of our Sienna Plantation location,” said Dr. Michael (Derek) Caraway, Area Medical ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... 2017  Diplomat Pharmacy, Inc. (NYSE: DPLO), the nation,s largest ... June 30, 2017.  All comparisons, unless otherwise noted, are to ... Second Quarter 2017 Highlights include: ... an increase of 3.5% Total prescriptions dispensed ... of 7.5% versus 7.6% Gross profit ...
(Date:8/4/2017)... , Aug. 4, 2017 The search for ... after a physician/patient consult has long been the goal ... a notable focus of the largest meeting of lab ... to healthcare market research firm Kalorama Information.  The firm ... (POCT) offerings or related supplies and software were at ...
(Date:8/3/2017)...  Opioid addiction and other drugs of abuse, blood ... threatening outcomes, were problems taken on directly as laboratory ... support them, met this week. This according to Kalorama ... of abuse, procalcitonin and acute kidney injury were key ... meeting in San Diego, CA. ...
Breaking Medicine Technology: