Navigation Links
Stem Cells Repair Damaged Corneas in Mice
Date:4/10/2009

Procedure may someday replace transplants in people, experts say

FRIDAY, April 10 (HealthDay News) -- Stem cells injected into the eyes of mice with defective corneas returned the corneas to a more normal appearance, a new study has found.

Researchers hope the procedure might one day be an alternative to corneal transplants in humans. About 40,000 such transplants are done each year in the United States.

"The stem cells took the scar-like matrix, remodeled it and made it more like normal," said senior investigator James Funderburgh, an associate professor of ophthalmology at the University of Pittsburgh. "We were surprised and delighted."

A report on the study is in the April 9 online edition of the journal Stem Cells.

The cornea is the transparent, front layer of the eye that serves as a protective barrier and, along with the lens, helps focus light. Corneas can develop scar tissue from chronic inflammation caused by infections or other conditions and by injuries, such as chemical or thermal burns or other trauma.

Scar tissue can cause the cornea to lose its transparency, preventing it from focusing light, and this can lead to a loss of visual acuity, including cloudy, hazy vision sometimes described as looking through frosted glass.

"The only effective therapy is corneal transplant," Funderburgh said.

Several years ago, using human cadavers, Funderburgh and his colleagues collected stem cells from the stroma, a matrix of collagen fibers that gives the cornea its strength.

In a healthy cornea, the collagen fibers run parallel to each other and are highly organized. In a damaged cornea, the matrix is irregular and disorganized, he said.

After growing stem cell cultures in the lab, the researchers injected the stem cells into the eyes of mice bred to have defective corneas that mimic scar tissue in humans.

After three months, the stem c
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2 3

Related medicine news :

1. Molecule prompts damaged heart cells to repair themselves after a heart attack
2. Patient Movement Forms in Opposition to FDA Position that the Patient's Own Stem Cells are Drugs
3. Not just a long-distance relationship: Immune cells in skin fight off infection better than the rest
4. New technique invented to reveal pancreatic stem cells
5. JHU researcher discovers brain cells have memory
6. Brain Cells Give New Clues to Alzheimers
7. Human Heart Can Make New Cells
8. Cancer stem cells generated by cancer outgrowth
9. Active Ingredient in Marijuana Kills Brain Cancer Cells
10. Patients Own Stem Cells Might Treat Heart Attack
11. Korean Stem Cells Allow Artist to Paint Again
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem Cells Repair Damaged Corneas in Mice
(Date:5/24/2013)... 2013 Wednesday, 15th May 2013 | 10am ... to access webinar playback: http://bit.ly/10Rt0ZH , Ongoing regulatory ... markets. Across the globe and particularly in Europe, a number ... M&A activity . For dealmakers, understanding how the likes of ... Tax’ affects your corner of the market will give you ...
(Date:5/24/2013)... Scott Ryan Tischler of Tischler Brothers Fitness ... lbs. of fat in just over a year. Not ... the importance of exercising. Scott also taught Troy the ... 7 rules of healthy eating and having a regular ... , 1.    Find a distraction when a food craving attacks. ...
(Date:5/23/2013)... Macedon, NY (PRWEB) May 24, 2013 ... shows employee absentee patterns and reduces vacation conflicts. A ... a problem with vacation conflicts; now employees and managers ... longer have any problems. Attendance is important to us ... slackers are exposed. That may seem harsh but it ...
(Date:5/23/2013)... blood glucose is associated with poor outcomes in hospitalized ... control hyperglycemia is a common practice in hospitals. But ... and even shows harms associated with the use of ... Clinical Guidelines Committee in a new evidence-based paper published ... Quality . , "Clinicians caring for hospitalized patients must ...
(Date:5/23/2013)... In his pulse-quickening novel, “The AIDS Covenant” (published ... trust your government?” , In the “The AIDS Covenant,” readers ... London ’s Heathrow Airport. His American colleague, Alan Milner ... him to arrive at his Sierra Nevada ski-lodge. ... doubts about the government’s report. When Alan learns that Owen ...
Breaking Medicine News(10 mins):Health News:Register to Access Webinar Playback - The Impact of Financial Regulation on M&A in 2013 2Health News:Register to Access Webinar Playback - The Impact of Financial Regulation on M&A in 2013 3Health News:New Attendance, Vacation and Training Tracker Board Reduces Employee Conflicts and Improves Attendance 2Health News:ACP issues recommendations for management of high blood glucose in hospitalized patients 2Health News:New Book “The AIDS Covenant” by Roy Harris Delivers Intriguing, Captivating Story 2
... the most common hormone imbalance in women of reproductive age, ... A (BPA), found in many plastic household items, according to ... The Endocrine Society,s 92nd Annual Meeting in San Diego. ... elevated and associated with higher levels of male hormones in ...
... who die by suicide are more likely to use violent ... as a drug overdose), new research suggests. In a ... substance use disorders, researchers found that, despite having access to ... used violent means. The study was reported in the July ...
... recent revelation that the chair of the board of ... executive until April 2010 sends an unfortunate message to ... priority, states an editorial http://www.cmaj.ca/cgi/doi/10.1503/cmaj.100850 in CMAJ ... simply no place for the tobacco industry on the ...
... months of exclusive breast-feeding best, , MONDAY, June 21 ... immune system boost to infants, helping to prevent respiratory ... , Babies who were breast-fed exclusively for 4 months, ... had a reduced risk of respiratory and gastrointestinal infections ...
... have examined the differences between spirituality and religion ... is exploring these differences by determining how youth ... spirituality can help reveal its impact on adolescent ... in terms of positive behaviors, feelings and relationships. ...
... that used to be feminized after chemicals, such as the ... Plant and into Boulder Creek, are taking longer to become ... according to a new study. The results will be presented ... Diego. Although the levels of the chemicals that the ...
Cached Medicine News:Health News:Women with polycystic ovary syndrome have higher BPA blood levels 2Health News:Violence, not overdose, the likely method of suicide in veterans with substance use disorders 2Health News:CMAJ calls for resignation of IDRC chair Barbara McDougall 2Health News:Breast Milk Reduces Infections in Babies 2Health News:Breast Milk Reduces Infections in Babies 3Health News:Youth define spirituality in terms of positive behaviors, connections 2Health News:Chemicals remaining after wastewater treatment change the gender of fish 2
(Date:5/23/2013)... May 23, 2013  MGC Diagnostics Corporation (NASDAQ: ... technology company, today scheduled a conference call to discuss ... year 2013, ended April 30, 2013. The call will ... 2013. The Company will report financial results for the ... close on Thursday, May 30, 2013. ...
(Date:5/23/2013)... 23, 2013 More than half of women ... from chemotherapy and still have excellent outcomes. To educate ... of the largest sources of online consumer information about ... Facebook page provide recently diagnosed women with information sources, ... chemotherapy. "We anticipate these innovative social media ...
(Date:5/23/2013)... May 23, 2013  Texas, premier physician associations today ... the survival tools they need to provide demonstrably better ... health care marketplace. "I am confident the ... practices," said Stephen L. Brotherton , ... Texas doctors are determined to make ...
Breaking Medicine Technology:MGC Diagnostics Corporation to Report Second Quarter Fiscal 2013 Financial Results on Thursday, May 30, 2013 2Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 2Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 3TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4
For the quantitative in vitro determination of lithium in serum and plasma. Wavelength: 550 nm. Linear range: up to 4 mm....
... Genegnome HR is a new dedicated high ... Genegnome completely automates the process of imaging ... and is extremely easy to use, thanks ... powerful imaging hardware. Based on the standard ...
... range of Platelet aggregometers allows to ... particular needs. Single, dual and four ... recorder outputs or digital computer outputs. ... aggregometers, which measure platelet aggregation in ...
... The PAP-4CD is a four channel platelet ... data system. Operating in conjunction with Microsoft ... color display of tests, automatic storage of ... data management. Four test modes are available: ...
Medicine Products: