Navigation Links
Stem Cells Fix Bladder Leakage in Mice, Study Finds
Date:8/21/2012

TUESDAY, Aug. 21 (HealthDay News) -- Stem cells from amniotic fluid might one day help treat stress urinary incontinence, a condition caused by damaged pelvic floor muscles in which bladder leakage is brought on by exercise, coughing or simply laughing, a new study involving mice suggests.

Researchers in Korea found that this new technique repaired the damaged pelvic floor muscles in the mice, and kept the condition from recurring.

Results obtained in animal studies do not necessarily apply to humans, however, and much more research is needed before this might be considered a viable treatment for people.

Looking for an alternative to surgery to treat stress urinary incontinence, the scientists explored the use of stem cells to repair the weak muscles that cause bladder leakage. To do this in a noninvasive way, they used stem cells from amniotic fluid collected during routine amniocentesis (prenatal testing of amniotic fluid).

"These stem cells ... have the ability to become muscle cells when grown under the right conditions," explained the study's leaders, James Yoo and Tae Gyun Kwon, from Kyungpook National University, in a news release. "We found that the stem cells were able to survive for seven days inside the mice but by 14 days they had all disappeared. Nevertheless, they were able to induce regeneration of the mouse's own urethral sphincter muscle."

The study revealed the stem cells were able to strengthen the muscles of the pelvic floor. This regenerated muscle also had the right nerve connections. The researchers added that amniotic stem cells do not appear to cause an immune response, such as rejection or tumor growth. Exactly how the stem cells are able to regenerate the muscles remains unclear, they noted.

Stress urinary incontinence is common among women during and after pregnancy and in women aged 40 and older. The study authors noted that men also can develop the condition, particularly those who have undergone prostate surgery.

Current treatments for stress urinary incontinence include a combination of surgery, weight loss, pelvic floor exercises and bladder training.

The study was published Aug. 20 in the journal BMC Medicine.

More information

The U.S. National Institutes of Health provides more information on stem cells.

-- Mary Elizabeth Dallas

SOURCE: BioMed Central, news release, Aug. 20, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Long-term methadone treatment can affect nerve cells in brain
2. Researchers aim to grow salivary glands using patients own cells
3. Moffitt Cancer Center researchers discover how cancer cells hijack a mechanism to grow
4. Human embryos frozen for 18 years yield viable stem cells suitable for biomedical research
5. Theranostic imaging offers means of killing prostate cancer cells
6. The making and unmaking of stem-like, aggressive breast cancer cells
7. Study Uses Stem Cells to Boost Red Blood Cell Production
8. Lawson research suggests breast cancer cells have discerning tastes
9. Brains stem cells eavesdrop to find out when to act
10. Northwestern researchers investigate treatment for tumor cells in spinal fluid
11. Evidence Grows That Cancer Has Its Own Stem Cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... TherapySites, the leading ... with Tennessee Counseling Association. This new relationship allows TherapySites to continue ... Association, adding exclusive benefits and promotional offers. , "TCA is extremely excited about ...
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... ... cutting edge technology to revolutionize the emergency ambulance transport experience for the millions ... aware of how Uber has disrupted the taxi industry through the use of ...
(Date:6/26/2016)... PLAINSBORO, N.J. (PRWEB) , ... June 27, 2016 , ... ... same sources, yet in many ways they remain in the eye of the beholder, ... Oncology (EBO), a publication of The American Journal of Managed Care. For the full ...
(Date:6/26/2016)... Aliso Viejo, California (PRWEB) , ... June 26, 2016 , ... ... for Final Cut Pro X. , "Film editors can give their videos a whole ... artistically," said Christina Austin - CEO of Pixel Film Studios. , ProSlice Levels ...
(Date:6/26/2016)... ... ... Kasmer, a legally blind and certified personal trainer is helping to develop a weight loss ... plans to fix the two major problems leading the fitness industry today:, ... , They don’t eliminate all the reasons people quit their exercise program ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Revolutionary ... Oticon , industry leaders in advanced audiology ... of Oticon Opn ™, the world,s first internet ... possibilities for IoT devices.      (Photo: ... introduces a number of ,world firsts,: , ...
(Date:6/23/2016)... Research and Markets has announced the addition ... States, China, Japan, Brazil, United Kingdom, Germany, France, Italy, ... Surgical Procedure Volumes: Global ... surgical procedure volume data in a geographic context. The ... of growth drivers and inhibitors, including world population growth, ...
(Date:6/23/2016)... WASHINGTON , June 23, 2016  The ... Pharmaceuticals has joined the health policy research organization ... Steven Romano , MD, senior vice president and ... his company,s representative on the NPC Board of ... are pleased that Mallinckrodt has joined us in ...
Breaking Medicine Technology: