Navigation Links
Stem Cells Fix Bladder Leakage in Mice, Study Finds
Date:8/21/2012

TUESDAY, Aug. 21 (HealthDay News) -- Stem cells from amniotic fluid might one day help treat stress urinary incontinence, a condition caused by damaged pelvic floor muscles in which bladder leakage is brought on by exercise, coughing or simply laughing, a new study involving mice suggests.

Researchers in Korea found that this new technique repaired the damaged pelvic floor muscles in the mice, and kept the condition from recurring.

Results obtained in animal studies do not necessarily apply to humans, however, and much more research is needed before this might be considered a viable treatment for people.

Looking for an alternative to surgery to treat stress urinary incontinence, the scientists explored the use of stem cells to repair the weak muscles that cause bladder leakage. To do this in a noninvasive way, they used stem cells from amniotic fluid collected during routine amniocentesis (prenatal testing of amniotic fluid).

"These stem cells ... have the ability to become muscle cells when grown under the right conditions," explained the study's leaders, James Yoo and Tae Gyun Kwon, from Kyungpook National University, in a news release. "We found that the stem cells were able to survive for seven days inside the mice but by 14 days they had all disappeared. Nevertheless, they were able to induce regeneration of the mouse's own urethral sphincter muscle."

The study revealed the stem cells were able to strengthen the muscles of the pelvic floor. This regenerated muscle also had the right nerve connections. The researchers added that amniotic stem cells do not appear to cause an immune response, such as rejection or tumor growth. Exactly how the stem cells are able to regenerate the muscles remains unclear, they noted.

Stress urinary incontinence is common among women during and after pregnancy and in women aged 40 and older. The study authors noted that men also can develop the condition, particularly those who have undergone prostate surgery.

Current treatments for stress urinary incontinence include a combination of surgery, weight loss, pelvic floor exercises and bladder training.

The study was published Aug. 20 in the journal BMC Medicine.

More information

The U.S. National Institutes of Health provides more information on stem cells.

-- Mary Elizabeth Dallas

SOURCE: BioMed Central, news release, Aug. 20, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Long-term methadone treatment can affect nerve cells in brain
2. Researchers aim to grow salivary glands using patients own cells
3. Moffitt Cancer Center researchers discover how cancer cells hijack a mechanism to grow
4. Human embryos frozen for 18 years yield viable stem cells suitable for biomedical research
5. Theranostic imaging offers means of killing prostate cancer cells
6. The making and unmaking of stem-like, aggressive breast cancer cells
7. Study Uses Stem Cells to Boost Red Blood Cell Production
8. Lawson research suggests breast cancer cells have discerning tastes
9. Brains stem cells eavesdrop to find out when to act
10. Northwestern researchers investigate treatment for tumor cells in spinal fluid
11. Evidence Grows That Cancer Has Its Own Stem Cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Those who ... with these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, ... Marne, Michigan, has released tools for healthy coping following a traumatic event. , Trauma ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Sessions in Dallas that it will receive two significant new grants to support ... as PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists ...
(Date:6/24/2016)... ... 2016 , ... Comfort Keepers® of San Diego, CA is excited to announce ... program to drive cancer patients to and from their cancer treatments. Comfort Keepers ... of life and ongoing independence. Getting to and from medical treatments is one ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. ... articles published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic ... Frederick area economy by obtaining investment capital for emerging technology companies. SCP ... that have already resulted in more than a million dollars of capital investment ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 Research ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural Health ... Structural electronics involves electronic and/or electrical ... structures, replacing dumb structures such as vehicle bodies ...
(Date:6/24/2016)... 24, 2016 According to a ... (Standard Pen Needles, Safety Pen Needles), Needle Length (4mm, ... Hormone), Mode of Purchase (Retail, Non-Retail) - Trends & ... studies the market for the forecast period of 2016 ... 2.81 Billion by 2021 from USD 1.65 Billion in ...
(Date:6/23/2016)... , June 23, 2016 Research ... Devices Global Market - Forecast to 2022" report to ... the treatment method for the patients with kidney failure, it ... excess fluid from the patient,s blood and thus the treatment ... potassium and chloride in balance. Increasing number ...
Breaking Medicine Technology: