Navigation Links
Stem Cells Finally Found in Pancreas
Date:1/24/2008

n type 2 diabetes, the loss of beta cells is more gradual.

Islet-cell transplantation, in which islets are transferred from one person to another, is performed today but is limited in scope because of a shortage of donors, according to the study.

The very existence of pancreatic stem cells is controversial. A recent study out of Harvard found that the major source of new beta cells in adult mice was preexisting beta cells, not stem cells. The finding reduced the urgency to track down pancreatic stem cells.

"If stem cells didn't contribute, what was the point," said Dominguez-Bendala.

For this study, Heimberg and his colleagues cut off the duct that drains digestive enzymes from the pancreas in mice. Within two weeks, the number of beta cells in the pancreas doubled.

Not only did the number of beta cells increase, the mice started producing more insulin.

"When damaged a specific way, it triggered stem cells" production, Dominguez-Bendala said.

The newly identified stem cells were almost identical to embryonic beta cell progenitors. In fact, the gene Neurogenin 3 (Ngn3), which plays a role in embryonic development of the pancreas, is also involved in the formation of these new beta cells, the researchers said.

"This is a model of regeneration no one has tested before," Dominguez-Bendala said. "From a basic science point of view, it's very exciting. It opens the door to potential therapies. If we could trigger regeneration, that would be fantastic."

More information

For more on pancreatic islet transplantation, visit the U.S. National Diabetes Information Clearinghouse.



SOURCES: Juan Dominguez-Bendala, Ph.D., director, Stem Cell Development for Translational Research, Diabetes Research Institute, and assistant professor, surgery, University of
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
2. Brain cells work differently than previously thought
3. Embryonic Stem Cells Repair Human Heart
4. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
5. Circulating fats kill transplanted pancreas cells, study shows
6. Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells
7. Melanoma drug revs immune cells but cancer cells ignore it
8. Scientists explain how insulin secreting cells maintain their glucose sensitivity
9. Embryonic stem cells used to grow cartilage
10. Molecular probe paints cancer cells in living animals, Stanford researchers find
11. USC researcher identifies stem cells in tendons that regenerate tissue in animal model
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem Cells Finally Found in Pancreas
(Date:4/17/2015)... 2015 John Evans, a Gardant affordable ... Patio from 2 p.m. to 3 p.m. on April ... Executive Ct. in Pekin, Illinois, serves older adults of ... help to maintain their independence. , Becky Baker will ... will be served during the luau. , For more ...
(Date:4/17/2015)... Beach, California (PRWEB) April 17, 2015 ... surgeon Dr. Kevin Sadati of the Gallery ... of Orange County’s top beauty experts. The publication ... neck lift, facial stem cell fat grafting, eyelid surgery, ... to facial plastic surgery has resulted in ...
(Date:4/17/2015)... (PRWEB) April 17, 2015 “We have seen ... of the past and present,” said Chaplain Shawn Kafader of ... hadn’t felt like they had anything to contribute have created ... has overseen a new art therapy program that was launched ... a Masters student from School of the Art Institute in ...
(Date:4/17/2015)... CA (PRWEB) April 17, 2015 Consumers ... insurance protection without modifications can now use the Insurance ... general life insurance policy rates that are featured by ... The standard plans that are offered are mixed between ... aged 18 to 79. There are now term, universal ...
(Date:4/17/2015)... As a board-certified orthopedic surgeon, Dr. ... of platelet-rich plasma (PRP) and stem cell ... known for its world-class care of injury-caused and chronic ... lacking in many other physicians offering regenerative medicines. ... for pain management and rehabilitation. Dr. Meier and MOSM ...
Breaking Medicine News(10 mins):Health News:John Evans Supportive Living Community Prepares for Party on the Patio 2Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 2Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 3Health News:Healing At Friendship Village Due To Art Therapy 2Health News:General Life Insurance Policy Rates Added to Quotation System at Insurance Website Online 2Health News:Platelet-Rich Plasma, Stem Cell Therapy Now Offered By Dr. Meier At MOSM in Beverly Hills, California 2Health News:Platelet-Rich Plasma, Stem Cell Therapy Now Offered By Dr. Meier At MOSM in Beverly Hills, California 3
... More than 250 experts have got together for a conference ... the curtain raiser, of what is going to be a ... Forum was instituted in 2005 by the parliament's corporate body ... channels of communication between politicians, academics and international organizations. ...
... the common cause of amnesia, also prevents victims from thinking ... present. ,Researchers, reporting their study in Tuesday's ... the Wellcome Trust Centre for Neuroimaging, University College London, examined ... that is crucial in learning and memory. ...
... a research they will back all the way through. , ... with the aim of getting the recipient pregnant. // ,The ... difficulties though. ,The wombs would come from dead donors, ... the recipient gives birth so she would not need anti-rejection drugs ...
... Australia health providers is busy counting its losses. ... doctors resort to rorting or over servicing, //by prescribing ... ,The loss in figure s caused by over billing ... body releases its 'Report to the Professions', which looks ...
... be best for your health. A new study found that ... to the bacterium Helicobacter pylori, //and younger siblings from large ... type of stomach cancer. ,These latest findings are ... who were followed over a 28-year period. The researchers found ...
... linked a structural protein called nestin to a particularly ... that could lead to earlier detection and better treatment.// ... Research, researchers from Dartmouth Medical School demonstrate that nestin ... breast tumors, a highly aggressive cancer with similarities to ...
Cached Medicine News:Health News:Amnesia Halts Future Thinking: Study 2Health News:Uterus Transplant- A Future Reality 2Health News:Link Between Family Size and Stomach Cancer Found 2Health News:Link Between Family Size and Stomach Cancer Found 3Health News:Selective Marker Found to Indicate Aggressive Form of Breast Cancer 2Health News:Selective Marker Found to Indicate Aggressive Form of Breast Cancer 3
(Date:4/17/2015)... DUBLIN , Apr. 16, 2015 Research and ... addition of the "Corporate Reputation of Pharma in ... - 1st Edition" report to their offering. ... has compared opinions on the corporate reputation of the ... in mental health with the views of patient organisations ...
(Date:4/17/2015)... , April 17, 2015 Bionomics Limited ... and development of innovative therapeutics for the treatment of ... announced the presentation of data from three of its ... for Cancer Research (AACR) 106 th Annual Meeting ... Philadelphia, PA USA. The ...
(Date:4/16/2015)... Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: VNDA ... commercialization of products for the treatment of central nervous ... the first quarter of 2015 on Wednesday, May 6, ... Company will host a conference call at 4:30 PM ... management will discuss the first quarter 2015 financial results ...
Breaking Medicine Technology:Corporate Reputation of Pharma in 2014 - The Perspective of Mental Health Patient Groups - 1st Edition 2Corporate Reputation of Pharma in 2014 - The Perspective of Mental Health Patient Groups - 1st Edition 3Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 2Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 3Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 4Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 5Vanda Pharmaceuticals to Announce First Quarter 2015 Financial Results on May 6, 2015 2
... 2011 Life Technologies Corporation (Nasdaq: ... semiconductor sequencing chip will be available for early access ... and analysis software, providing up to 1Gb of data ... 314 chip introduced two months ago with the ...
... Omnicell, Inc ., (Nasdaq: OMCL ... healthcare facilities, today announced the results of a survey ... to identify trends in requirements for vendor interoperability and ... that the majority of hospitals recognize the critical role ...
Cached Medicine Technology:Life Technologies to Launch Ion 318 Chip in Second Half of 2011 with 1Gb of Data Output 2Life Technologies to Launch Ion 318 Chip in Second Half of 2011 with 1Gb of Data Output 3Life Technologies to Launch Ion 318 Chip in Second Half of 2011 with 1Gb of Data Output 475 Percent of Hospital IT Leaders View Interoperability Between Vendor Systems as Critical to Operational Effectiveness in Healthcare Settings 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: