Navigation Links
Stem Cells Being Tested to Fight Pancreatic Cancer
Date:10/14/2009

It may be possible to stop tumor growth without harmful therapies, study suggests

WEDNESDAY, Oct. 14 (HealthDay News) -- New research is moving scientists closer to their goal of treating pancreatic cancer by killing tumors without hurting healthy tissue.

The researchers, who were scheduled to report their findings at the American College of Surgeons Clinical Congress, Oct. 11-15 in Chicago, have created a bioengineered "construct" that uses stem cells derived from bone marrow and a genetic product that stops tumor growth.

Pancreatic cancer requires stem cells in order to grow. The "Trojan horse" created by the researchers essentially confuses cancer cells and makes them produce a toxic product.

The findings could in time lead to better treatments for pancreatic cancer, which is often fatal. According to the National Cancer Institute, 43,000 people in the United States are diagnosed with the disease each year, and 35,000 people die.

"The prognosis of advanced pancreatic cancer is so devastating that even a small effect on prolongation and quality of life would be a tremendous outcome for the patient," study author Dr. Claudius Conrad of Massachusetts General Hospital in Boston, said in a news release from the American College of Surgeons.

One currently available treatment is chemotherapy, but it can make healthy cells become sick and can cause a variety of side effects, including bowel damage, diarrhea and nausea.

"We developed our concept of using stem cells to target tumor cells because the homing drive of aggressive tumors like pancreatic cancer is so strong that genetically engineered stem cells can help destroy the tumor," Conrad explained. "Also, the unique signals in the tumor microenvironment can help make the therapy cancer-specific once the modified stem cells have been homed."

To date, the research is still in preliminary stages and has been tested only in animals.

More information

Learn more about pancreatic cancer from the U.S. National Cancer Institute.



-- Randy Dotinga



SOURCE: American College of Surgeons, news release, Oct. 14, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New Way to Make Stem Cells?
2. New study resolves the mysterious origin of Merkel cells
3. Louisiana's TCA Cellular Therapy's Findings Reported at World Stem Cell Summit -- Patients' Legs Saved from Amputation Using Adult Stem Cells
4. Leukemia Cells May Hide in Fat Tissue
5. Immune Cells Offer Hope for Injured Lungs
6. Experimental drug lets B cells live and lymphoma cells die
7. STEMCELL Technologies Applauds Feeder-free Derivation of Human Induced Pluripotent Stem Cells
8. Diabetes Drug Kills Cancer Stem Cells in Combination Treatment in Mice
9. New type of adult stem cells found in the prostate may be involved in prostate cancer development
10. Biomedical Research Centre developing enhanced cells as therapies
11. Researchers Make Insulin-Producing Cells From Adult Skin Cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/30/2016)... , ... April 30, 2016 , ... Orlando-based Maximized Living ... they go for gold in Rio. Under the care of Maximized Living doctors ... , In an unprecedented showing, Maximized Living is sending the largest contingent of elite ...
(Date:4/29/2016)... (PRWEB) , ... April 29, 2016 , ... ... notified by the Accreditation Council for Graduate Medical Education (ACGME) that it has ... This is the first accreditation of three residency programs that Memorial is currently ...
(Date:4/29/2016)... ... 2016 , ... Dr. Bernie Siegel, (M.D.) world ... and MIRACLES") addresses touchy topics related to Death live on Dr. Carol ... Bernie Siegel, author of a plethora of essential books-to-read for physicians and all ...
(Date:4/29/2016)... ... , ... Spine Team Texas, a comprehensive spine physician group specializing in the ... has been invited to be a featured speaker at the Texas Society of the ... 30, 2016. , Dr. R. Scott McPherson, a physical medicine and rehabilitation specialist, ...
(Date:4/29/2016)... ... , ... Melanoma is the deadliest type of skin cancer. Although only about 1 percent of ... deaths. More than 10,000 people are expected to die of melanoma this year. The risk ... one of the most commonly diagnosed cancers in young women. A recent breakthrough in genetic ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... SHAWNEE, Kan. , April 27, 2016 /PRNewswire/ ... Martabano , a senior from the University of ... winner of the Bayer Excellence in Communication Award ... veterinary schools, which were awarded a total of ... Over the last four years, Bayer has provided ...
(Date:4/27/2016)... 27, 2016 Global  urinalysis ... billion by 2022, according to a new report ... (Logo: http://photos.prnewswire.com/prnh/20150105/723757 ) , ... efficiency and accuracy delivered by the new generation ... novel urinalysis instruments and consumables. For instance, the ...
(Date:4/26/2016)... Hill-Rom Holdings, Inc. (NYSE: HRC ) invites you ... 41 st Annual Health Care Conference on Wednesday, May ... invited to listen to the live discussion via the internet ... http://edge.media-server.com/m/p/mr4uxgas . A recorded replay of the discussion will ... and accessible at the links above until August 1, 2016. ...
Breaking Medicine Technology: