Navigation Links
Stem Cell Transplants in Mice Show Promise for Lou Gehrig's Disease
Date:1/9/2013

WEDNESDAY, Jan. 9 (HealthDay News) -- Stem cells may one day hold promise for a new treatment for people with amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease, new animal research suggests.

A study of mice found that stem cell transplantation extended their lifespan by 20 days and improved their neuromuscular function by 15 percent.

"There have been remarkable strides in stem cell transplantation when it comes to other diseases, such as cancer and heart failure," study author Dr. Stefania Corti, of the University of Milan in Italy, said in a news release from the American Academy of Neurology.

"ALS is a fatal, progressive, degenerative disease that currently has no cure," Corti said. "Stem cell transplants may represent a promising avenue for effective cell-based treatment for ALS and other neurodegenerative diseases."

The mice involved in the study had an animal version of ALS. They were injected with human neural stem cells taken from human induced pluripotent stem cells -- adult cells genetically reprogrammed to resemble embryonic stem cells.

These injected stem cells traveled to the spinal cord of the mice, where they matured and multiplied, improving the rodents' lifespan and neuromuscular function.

"Our study shows promise for testing stem cell transplantation in human clinical trials," Corti concluded.

Results achieved in animal tests, however, do not necessarily apply to humans.

The study's findings, released Jan. 9, are scheduled for presentation in March at the American Academy of Neurology's annual meeting in San Diego. Data and conclusions presented at medical meetings should be viewed as preliminary until published in a peer-reviewed journal.

People with ALS eventually lose their strength and cannot move or breathe. The American baseball player Lou Gehrig died of the disease in 1941.

More information

The U.S. National Institute of Neurological Disorders and Stroke provides more information on Lou Gehrig's disease.

-- Mary Elizabeth Dallas

SOURCE: American Academy of Neurology, news release, Jan. 9, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Boomers With Hepatitis C Boosting Demand for Liver Transplants
2. Brain cell transplants in early 2013
3. Half-Match Marrow Transplants Help Some With Sickle Cell
4. Half-match bone marrow transplants wipe out sickle cell disease in selected patients
5. HIV Undetectable in 2 Men After Bone Marrow Transplants: Study
6. Noninvasive imaging technique may help kids with heart transplants
7. Protecting the hearts of those waiting for kidney and liver transplants
8. Ovarian Transplants May Preserve Fertility in Young Cancer Survivors
9. U.S. Liver Transplants Declining
10. First, Second Kidney Transplants Have Similar Success: Study
11. More changes in health care needed to fulfill promise of health information technology
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem Cell Transplants in Mice Show Promise for Lou Gehrig's Disease
(Date:10/13/2017)... ... October 13, 2017 , ... While it’s often important ... problem. Fortunately, an inventor from Austin, Texas, has identified a solution. , She developed ... darkness or restricted lighting. As such, it eliminates the need to turn on a ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... PurhealthRX ... CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will ... and providing a CBD form that can be easily incorporated into liquid products, while ...
(Date:10/13/2017)... ... , ... Apple Rehab Shelton Lakes , which specializes in the delivery ... as part of a disaster drill on October 3rd. , Apple Rehab participated with ... Manager, as well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). ...
(Date:10/13/2017)... ... , ... Ellevate Network, the leading network for professional women, brought together some ... at their inaugural Summit in New York City in June. The event was livestreamed ... over 3 million. To watch the Mobilize Women video, click here . ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... giving viewers the lowdown on sciatica in a new episode of "Success Files," ... on current events and innovation and investigates each subject in-depth with passion and ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Oct. 2, 2017 The Rebound mobile app is ... to reverse the tide of prescription drug addiction. The app ... medicine intake and stepping down their dosage in a safe, ... in December 2017; the first 100,000 people to sign up ... http://www.rebound-solution.com/ ...
(Date:9/25/2017)... , Sept. 25, 2017   Montrium ... Master File solutions, today—from the IQPC Trial Master ... , NL)—announced that EastHORN Clinical Services has ... clinical programs and TMF management. EastHORN, a leading ... eTMF platform to increase transparency to enable greater ...
(Date:9/19/2017)... ANN ARBOR, Mich. , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical ... the precise destruction of targeted tissues, announced three leadership team developments today:   ... Josh Stopek, PhD ... ... Veteran medical device executive ...
Breaking Medicine Technology: