Navigation Links
Stem Cell Transplants in Mice Show Promise for Lou Gehrig's Disease
Date:1/9/2013

WEDNESDAY, Jan. 9 (HealthDay News) -- Stem cells may one day hold promise for a new treatment for people with amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease, new animal research suggests.

A study of mice found that stem cell transplantation extended their lifespan by 20 days and improved their neuromuscular function by 15 percent.

"There have been remarkable strides in stem cell transplantation when it comes to other diseases, such as cancer and heart failure," study author Dr. Stefania Corti, of the University of Milan in Italy, said in a news release from the American Academy of Neurology.

"ALS is a fatal, progressive, degenerative disease that currently has no cure," Corti said. "Stem cell transplants may represent a promising avenue for effective cell-based treatment for ALS and other neurodegenerative diseases."

The mice involved in the study had an animal version of ALS. They were injected with human neural stem cells taken from human induced pluripotent stem cells -- adult cells genetically reprogrammed to resemble embryonic stem cells.

These injected stem cells traveled to the spinal cord of the mice, where they matured and multiplied, improving the rodents' lifespan and neuromuscular function.

"Our study shows promise for testing stem cell transplantation in human clinical trials," Corti concluded.

Results achieved in animal tests, however, do not necessarily apply to humans.

The study's findings, released Jan. 9, are scheduled for presentation in March at the American Academy of Neurology's annual meeting in San Diego. Data and conclusions presented at medical meetings should be viewed as preliminary until published in a peer-reviewed journal.

People with ALS eventually lose their strength and cannot move or breathe. The American baseball player Lou Gehrig died of the disease in 1941.

More information

The U.S. National Institute of Neurological Disorders and Stroke provides more information on Lou Gehrig's disease.

-- Mary Elizabeth Dallas

SOURCE: American Academy of Neurology, news release, Jan. 9, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Boomers With Hepatitis C Boosting Demand for Liver Transplants
2. Brain cell transplants in early 2013
3. Half-Match Marrow Transplants Help Some With Sickle Cell
4. Half-match bone marrow transplants wipe out sickle cell disease in selected patients
5. HIV Undetectable in 2 Men After Bone Marrow Transplants: Study
6. Noninvasive imaging technique may help kids with heart transplants
7. Protecting the hearts of those waiting for kidney and liver transplants
8. Ovarian Transplants May Preserve Fertility in Young Cancer Survivors
9. U.S. Liver Transplants Declining
10. First, Second Kidney Transplants Have Similar Success: Study
11. More changes in health care needed to fulfill promise of health information technology
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem Cell Transplants in Mice Show Promise for Lou Gehrig's Disease
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and ... their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took ... the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published ... unfamiliar with. The article goes on to state that individuals are now more comfortable ... less common operations such as calf and cheek reduction. The Los Angeles area medical ...
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... June ... about the dangers associated with chronic pain and the benefits of holistic treatments, ... individuals who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association (PHA) ... will receive two significant new grants to support its work to advance research ... anniversary by recognizing patients, medical professionals and scientists for their work in fighting ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 Roche (SIX: RO, ROG; OTCQX: ... its Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated ... shock. With this clearance, Roche is the first IVD ... solution for sepsis risk assessment and management. ... and PCT levels in blood can aid clinicians in ...
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
(Date:6/23/2016)... June 23, 2016 The vast majority of ... dialysis facility.  Treatments are usually 3 times a week, ... visit, including travel time, equipment preparation and wait time. ... especially grueling for patients who are elderly and frail.  ... nursing and rehabilitation centers for some duration of time. ...
Breaking Medicine Technology: