Navigation Links
Stem Cell Therapy Reversed Chemo-Linked Infertility in Male Monkeys
Date:11/2/2012

FRIDAY, Nov. 2 (HealthDay News) -- It might be possible one day to restore male fertility after cancer chemotherapy, new research with monkeys suggests.

Some cancer drugs are designed to destroy rapidly dividing cells, but can't tell the difference between cancer cells and other rapidly dividing cells in the body, including sperm-producing stem cells. As a result, these cells can be wiped out and leave the patient infertile.

"Men can bank sperm before they have cancer treatment if they hope to have biological children later in their lives. But that is not an option for young boys who haven't gone through puberty, can't provide a sperm sample and are many years away from thinking about having babies," study senior investigator Kyle Orwig, associate professor in the department of obstetrics, gynecology and reproductive medicine at the University of Pittsburgh School of Medicine, said in a university news release.

Orwig and his colleagues froze sperm-producing stem cells from young and adult male monkeys and then gave the monkeys chemotherapy drugs known to harm fertility. A few months later, each monkey's own sperm-producing stem cells were implanted into his testes.

The implanted stem cells restored production of sperm that successfully fertilized eggs to produce embryos.

The study was published Nov. 1 in the journal Cell Stem Cell.

"Many questions remain to be answered," Orwig said. "Should we re-introduce the [sperm-producing] cells as soon as treatment is over, or wait until the patient is considered cured of his disease or when he is ready to start a family? How do we eliminate the risk of cancer recurrence if we give back untreated cells that might include cancer cells? These are issues we still must work through, but this study does show us the concept is feasible."

Orwig noted that several centers in the United States and other countries are already freezing testicular tissue from you
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. KRAS gene mutation and amplification status affects sensitivity to antifolate therapy
2. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
3. Chemotherapy proves life-saving for some leukemia patients who fail induction therapy
4. Immunotherapy for elderly cancer patients finds new promise in drug combination
5. Therapy exploits addiction of leukemia cells
6. Intensity Modulated Radiation Therapy optimal for localized prostate cancer
7. Adding drug to standard chemotherapy provides no survival benefit for older lung cancer patients
8. Study Casts Doubt on Value of Pricey Prostate Cancer Therapy
9. 19th century therapy for Parkinsons disease may help patients today
10. New Psoriasis Drugs Not Much Better Than Standard Therapy, Study Finds
11. Xenotransplantation as a therapy for type 1 diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem Cell Therapy Reversed Chemo-Linked Infertility in Male Monkeys 
(Date:5/3/2015)... “ BolehVPN ” was featured on NewsWatch as part of ... technology products available to consumers. Scott Steinberg, a technology expert ... with viewers how to protect their private information. , A ... and even more so online. It helps everyone stay connected ... world. In terms of work, the internet makes things more ...
(Date:5/3/2015)... MA (PRWEB) May 03, 2015 SpineFrontier, ... clearance from the FDA to produce and market their ... device can be used in outpatient settings and is ... The alternate posterior approach has been extensively researched and ... 510k approval to use this approach in conjunction with ...
(Date:5/2/2015)... As one of only 30 Illinois companies to be ... and Recognition Program (SHARP) certification, Essentra Specialty Tapes ... Department of Labor to host this special event. ... the Occupational Safety and Health Administration’s (“OSHA”) Onsite Consultation ... or exceed all of the necessary regulations and standards, ...
(Date:5/2/2015)... (PRWEB) May 02, 2015 “ ActOn ” ... which takes a look at the latest and coolest applications ... the host of AppWatch and technology expert, conducted the app ... to get connected with organizations to make a difference. , ... are very few things that aren’t about money, which is ...
(Date:5/2/2015)... (PRWEB) May 02, 2015 We are ... The Delray Recovery Center as one of the Top ... known in the addiction treatment field for their ethics ... to innovate and to continue their educational efforts. The ... workplace environment, never forgetting their purpose – to help ...
Breaking Medicine News(10 mins):Health News:A Method to Keep Private Information Secure was Featured on NewsWatch Television 2Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 2Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 3Health News:An Application to Help People Make a Difference Was Featured on NewsWatch Television 2Health News:The Delray Recovery Center Named 2015 Top Workplace 2
... say , MONDAY, Oct. 29 (HealthDay News) High-dose ... prostate cancer patients, U.S. researchers say. , A team ... men with intermediate- to high-risk prostate cancer who underwent ... targets the tumor. , "IMRT is revolutionizing how we ...
... (brachytherapy) are just as effective at curing prostate cancer ... are in older men, according to a study presented ... the American Society for Therapeutic Radiology and Oncologys 49th ... minimally invasive procedure where a radiation oncologist places small ...
... type of drug called a pharmaceutical monoclonal antibody to ... effect of radiation therapy for lung cancer patients ... lives and improving their quality of life, according to ... October 29, 2007, at the American Society for Therapeutic ...
... of the National Institutes of Health, has awarded Rhode ... prevention and treatment of skeletal joint diseases. The 5-year ... (COBRE) for Skeletal Health and Repair at Rhode Island ... its academic partner, The Warren Alpert Medical School of ...
... will appear in conjunction with Kellogg Insight research,digest ... Kellogg School,of Management at Northwestern University today announced ... by David Dranove, the Kellogg School,s,Walter J. McNerney ... accessible at the following link:, http://insight.kellogg.northwestern.edu/index.php/codered ., ...
... global health and socio-economic factors ... YORK, Oct. 29 The 20th century ushered ... health. However, the,increased incidence and burden of major ... of tuberculosis, present critical,health challenges to the global ...
Cached Medicine News:Health News:Prostate Cancer Radiotherapy Won't Affect Sexual Function 2Health News:Radiation seeds effectively cure prostate cancer in young men 2Health News:Preventing lung scarring may extend lives of lung cancer patients 2Health News:Rhode Island Hospital lands $11.1M grant from National Institutes of Health 2Health News:Rhode Island Hospital lands $11.1M grant from National Institutes of Health 3Health News:Rhode Island Hospital lands $11.1M grant from National Institutes of Health 4Health News:Rhode Island Hospital lands $11.1M grant from National Institutes of Health 5Health News:Kellogg School of Management Announces 'Code Red' 2Health News:Charlie Rose Science Series to Focus on the Challenge of Researching and Implementing Effective Treatments for Diseases of the Developing World 2Health News:Charlie Rose Science Series to Focus on the Challenge of Researching and Implementing Effective Treatments for Diseases of the Developing World 3Health News:Charlie Rose Science Series to Focus on the Challenge of Researching and Implementing Effective Treatments for Diseases of the Developing World 4
(Date:5/1/2015)...   Heska Corporation (NASDAQ: HSKA - ... advanced veterinary diagnostic and other specialty veterinary products , ... present at the 16th Annual B. Riley & Co. Investor ... conference will be held May 12-14, 2015 at Lowes Hollywood ... will be available during the day on May 13 for ...
(Date:5/1/2015)... May 1, 2015 At the American Association ... Washington D.C. , Elekta will highlight ... enables clinicians to leverage the enormous amount of data ... conducted each year – to advance clinical research and ... is a cloud-based solution that allows practitioners to store, ...
(Date:5/1/2015)... May 1, 2015 Braeburn Pharmaceuticals ... current therapeutic focus beyond addiction and pain ... disorders. Braeburn has acquired an implantable, six-month ... risperidone for treatment of schizophrenia from Endo ... global rights to other potential applications of ...
Breaking Medicine Technology:Heska to Present at the 16th Annual B. Riley & Co. Investor Conference 2Elekta to showcase Leksell Gamma Knife Registry at AANS Annual Meeting 2Elekta to showcase Leksell Gamma Knife Registry at AANS Annual Meeting 3Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 2Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 3Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 4
... SILVER SPRING, Md., Sept. 14, 2011 The U.S. ... companies have agreed to halt distribution of amino-acid products ... of the Federal Food, Drug, and Cosmetic Act are ... West Duluth Distribution Co., a corporation doing business as ...
... Ga., Sept. 14, 2011 Greenway Medical Technologies, ... Inland Northwest Health Services (INHS) today announced an ... health record (EHR) and practice management solution ... practices requiring advanced care coordination and network interoperability. ...
Cached Medicine Technology:FDA: Minnesota Companies Agree to Halt Sale of Amino-acid Products with Unapproved Claims 2FDA: Minnesota Companies Agree to Halt Sale of Amino-acid Products with Unapproved Claims 3Greenway Partners With INHS to Advance EHR Adoption 2Greenway Partners With INHS to Advance EHR Adoption 3
... Biomet® Retrograde Femoral Nail ... the advantages of optimal ... straight nail designs. Furthermore, ... promote ease-of-use with desired ...
... latest in the Magnes line of biomagnetometer systems, ... full cortical coverage, provides the highest detector density ... of a wide range of neuronal activity. The ... detector configurations and can be equipped with radial ...
... Four-channel neurodiagnostic for basic ... EP. Incorporates a large 12.1" ... Advanced engineering and the latest ... performance and speed, advanced NCS ...
... stimulation is a non-invasive and painless method ... system. Cadwell Laboratories manufactures two magnetic stimulation ... Magnetic Stimulator (HSMS). The Hight Speed MES-10 ... up to 25 Hz at full power. ...
Medicine Products: