Navigation Links
Stem Cell Study Offers Hope for Targeting Tumors
Date:5/19/2009

In mice, genetically engineered cells killed cancer but spared healthy cells

TUESDAY, May 19 (HealthDay News) -- Genetically engineered adult stem cells, armed with a cancer-killing protein, have proven successful at targeting several types of tumors while sparing healthy cells, new research has found.

Stem cells carrying TNF-related apoptosis-inducing ligand (TRAIL) destroyed lung, squamous, breast and cervical cancer cells in laboratory cultures, according to British researchers. When tried on mice, the specialized cells shrunk subcutaneous breast tumors by about 80 percent, and when injected intravenously, they helped destroy about 38 percent of metastasized lung tumors in rodents.

The study results combined findings from two previous areas of research: one that found that mesenchymal stem cells (MSCs), which come from bone marrow, can work as messengers to tumors cells, and another that found TRAIL effective at killing cancer while sparing healthy cells.

"This is the first study to demonstrate a significant reduction in tumor burden with inducible TRAIL-expressing MSCs in a well-controlled and specifically directed therapy," the authors, Dr. Michael Loebinger and Dr. Sam M. Janes of the Centre for Respiratory Research at the University College London, noted in a news release from the American Thoracic Society. The findings were to be presented Tuesday in San Diego at the society's International Conference.

Despite the success, the authors said it could be at least two years before these specialized stem cells are tried on people. Loebinger noted, for example, that while the MSCs seem to be naturally drawn to the cancer cells, the reasons for this are not fully understood.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Kevin McKeever



SOURCE: American Thoracic Society, news release, May 19, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Stem Cell Study Offers Hope for Targeting Tumors
(Date:4/28/2017)... ... April 28, 2017 , ... Somnoware, a leading ... Word(TM) Online(TM), which enables sleep physicians to create and edit their interpretation reports. ... and provides a familiar interface that does not require additional training to use. ...
(Date:4/28/2017)... Grants Pass, OR (PRWEB) , ... April 28, ... ... Adetutu Ijose, http://www.foodsthathealdaily.com , http://www.wiredlifesolutions.com , “Computers are everywhere and ... Kleyne Hour Power of Water, Global Climate Change and Your Health on Voice ...
(Date:4/28/2017)... ... April 28, 2017 , ... The Texas Cord Blood ... to the labor and delivery team at Women’s Hospital at Renaissance in Edinburg for ... birth at the hospital and decide to donate. , “Women’s Hospital at Renaissance ...
(Date:4/28/2017)... ... ... Pastor and Overseer at The House of Yahweh in Abilene, Texas, has published a new ... not. Yisrayl says with so many titles and names for the Creator, it’s hard ... a little Scripture, backed with a lot of research, the truth is undeniable. , ...
(Date:4/28/2017)... , ... April 28, 2017 , ... NuevaCare, a leading ... diverse as Millbrae, Burlingame, and Palo Alto, is proud to announce information upgrades to ... to bookmark and read organized content on topics such as home care (generally) as ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 20, 2017  RXi Pharmaceuticals Corporation (NASDAQ: RXII), ... address significant unmet medical needs, today announced that ... consumer product development program, based on its proprietary ... Investigative Dermatology (SID) 76 th Annual Meeting.  ... the sciences relevant to skin health and disease ...
(Date:4/20/2017)... --  ZappRx, Inc ., a digital health company focused on ... it closed $25 million in Series B funding led by ... Seattle that is part of a ... B round included participation from SR One , who ... (formerly Google Ventures). As part of the financing, ...
(Date:4/20/2017)... , April 20, 2017 Eyevensys, ... the first non-viral gene expression technology that enables the ... eye to address a wide range of ophthalmic diseases, ... and Healthcare products Regulatory Agency (MHRA) to advance its ... ...
Breaking Medicine Technology: