Navigation Links
Stem Cell Research Offers Hope for Colon Cancer Vaccine
Date:10/7/2009

Mouse study suggests it may be possible to generate an immune response to cancer

WEDNESDAY, Oct. 7 (HealthDay News) -- Human stem cells may provide a means of creating a vaccine against colon cancer and other types of cancers, say American and Chinese scientists.

"Cancer and stem cells share many molecular and biological features. By immunizing the host with stem cells, we are able to 'fool' the immune system to believe that cancer cells are present and thus to initiate a tumor-combating immune program," Dr. Zihai Li, of the University of Connecticut Stem Cell Institute, said in a news release.

The research by Li and colleagues is the first to make the connection between human stem cells and colon cancer vaccination.

It has long been believed that immunizing people with embryonic materials may trigger an anti-tumor response by the immune system, but this theory has never advanced beyond animal research. The finding that human stem cells may help immunize against colon cancer is new and unexpected, the study authors pointed out.

In this study, the researchers vaccinated mice with human embryonic stem cells and found that the mice developed a consistent immune response against colon cancer cells. The vaccinated mice showed a dramatic decline in tumor growth, compared with non-vaccinated mice.

While human embryonic stem cells triggered an immune response, artificially induced pluripotent stem cells did not, a finding that challenges the theory that induced pluripotent stem cells are the same as human embryonic stem cells and may replace them at the forefront of stem cell research, Li and colleagues said.

The study was published online Oct. 7 in the journal Stem Cells.

"Although we have only tested the protection against colon cancer, we believe that stem cells might be useful for generating an immune response against a broad spectrum of cancers, thus serving as a universal cancer vaccine," co-author Dr. Bei Liu said in the news release.

More information

The U.S. National Cancer Institute has more about cancer vaccines.



-- Robert Preidt



SOURCE: Stem Cells, news release, Oct. 7, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2016)... ... May 06, 2016 , ... Featured ... provide a unique keynote address at the 2016 Learning Summit , June ... five community college students. Their stories—of complicated family issues, financial difficulties, and other ...
(Date:5/6/2016)... ... May 06, 2016 , ... Bluvault ( Bluvault Inc. ... offering for global clients of Coupa ( Coupa Software ) and other Cloud ... is a key component in the suite of innovative implementation services offered by ...
(Date:5/6/2016)... ... May 06, 2016 , ... Logically, spring weather, with ... when the weather is too cold, dry or hot, water on the eye surface ... absorb moisture from the surrounding air. There’s only one problem, according to radio show ...
(Date:5/6/2016)... ... May 06, 2016 , ... From the Speaker Podium to the Exhibit Floor ... its insights on managing Customers Engagement at SpeechTek 2016 Event, taking place May 23-25 ... deliver a Presentation on “5 Customer Engagement Strategies to improve Customer Satisfaction ...
(Date:5/6/2016)... ... May 06, 2016 , ... Expert ... . , Since launching in September, 2014 Sleepopolis has resided at Sleepopolis-mattress-reviews.com ... now include pillows, sheets, mattress toppers, bed frames, and more. , Founder and ...
Breaking Medicine News(10 mins):
(Date:5/5/2016)... , May 5, 2016 ... of the  "Europe Systemic Lupus Erythematosus Market ... to their offering.       (Logo: ... latest research Europe Systemic Lupus Erythematosus Market ... comprehensive insights into Systemic Lupus Erythematosus pipeline ...
(Date:5/4/2016)... 2016  It,s time for an upgrade. There are many medical recorders on the ... LCD, the illustrious DVMAXX HD  offers unparalleled connectivity and functionality.  Ampronix  is a ... class manufacturer of innovative technology.  Photo - http://photos.prnewswire.com/prnh/20160503/363416 ... ... ...
(Date:5/4/2016)... Yissum Research Development Company of the ... had signed an exclusive world-wide licensing and research agreement ... degradation and immunomodulatory drugs for cancer and immune dysfunction, ... first-in-class therapy for hematologic and solid malignancies. Financial terms ... novel technology was developed by Yinon Ben-Neriah , ...
Breaking Medicine Technology: