Navigation Links
Stem Cell, Bone Marrow Transplants Both Benefit Leukemia Patients
Date:2/1/2010

Little difference in survival found 10 years after therapies, study says

MONDAY, Feb. 1 (HealthDay News) -- Long-term survival rates are similar for leukemia patients who've had either peripheral blood stem cell (PBSC) or bone marrow transplants, a new European study says.

The study began with 329 leukemia patients who received either PBSC or bone marrow transplants from a matched sibling donor between 1995 and 1999. Detailed information was collected on all the patients who survived longer than three years after their transplant.

Ten years after transplantation, 49.1 percent of PBSC recipients and 56.5 percent of bone marrow transplant recipients were still alive. Chronic graft versus host disease was more common among PBSC transplant patients (73 percent) than among bone marrow transplant patients (54 percent), and more PBSC recipients needed immunosuppressive treatment five years after transplantation (26 percent vs. 12 percent). But this did not affect the PBSC recipients' general health status or their ability to return to work, the study found.

The researchers also noted a trend toward improved, but not statistically significant, leukemia-free survival and overall survival after bone marrow transplant in patients with acute leukemias. Among patients with acute lymphoblastic leukemia, 10-year leukemia-free survival probability was 28.3 percent in the bone marrow transplant group, compared with 13 percent in the PBSC transplant group.

In patients with acute myeloid leukemia, the rates were 62.3 percent for bone marrow transplant and 47.1 percent for PBSC transplant. For patients with chronic myeloid leukemia, the rates were 40.2 percent for bone marrow transplant and 48.5 percent for PBSC transplant.

"This update comparing two important stem cell sources did not find differences in survival after 10-year follow-up. However, subgroup analyses did reveal notable differences in survival in patients with acute leukemias between those who received allogeneic blood cells and those who received bone marrow, while no differences were seen in patients with chronic myeloid leukemia, the researchers wrote.

"Our observations support previous reports that different patient groups might still benefit from transplantation with bone marrow," they concluded.

The study was published online Jan. 31 in The Lancet Oncology.

More information

The U.S. National Cancer Institute has more about leukemia.



-- Robert Preidt



SOURCE: The Lancet Oncology, news release, Jan. 31, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Anti-Aging/Genetic Health Leader Suracell, Inc. Expands Internationally
2. ACell, Inc. Founder Mentioned on the Oprah Winfrey Show as Inventor of Powder for Healing Severed Fingers
3. StemCor Systems Receives FDA Clearance for Bone Marrow Harvesting System
4. Study on Plasma-Depleted Cord Blood Transplantation Receives Best Abstract Award From The National Marrow Donor Program
5. Oral drug sets a new survival standard for bone marrow cancer
6. Bone marrow cell transplants help nerve regeneration
7. StemCor Systems Announces Acquisition of Intellectual Property to Enhance Bone Marrow Aspiration Platform
8. Transplanted Bone Marrow Cells Aid Nerve Regeneration
9. Stem cells make bone marrow cancer resistant to treatment
10. Saturn Celebrates 11 Years of Helping Save Lives Through Blood, Marrow, Organ and Tissue Donation
11. New Interventional Radiology Treatment Shows Hope for People With Complications from Bone Marrow, Stem Cell Transplants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2017)... AREA, CA (PRWEB) , ... August 22, 2017 ... ... an accessible luxurious collection of unique masks and serums that perfectly fuse the ... skin care advancements, at the 2017 Indie Beauty Expo on August 23rd & ...
(Date:8/22/2017)... Davis, California (PRWEB) , ... August 22, 2017 ... ... implies that the key to good health is as simple as eating healthy ... to food—whether it be storing fat, making insulin, or breaking apart carbohydrates—depends not ...
(Date:8/22/2017)... ... August 22, 2017 , ... Pivot ... addition of Zack Tisch as the firm’s new Consulting Services Executive. Mr. Tisch ... firm’s national accounts, from assisting clients with initial vendor selection and pre-implementation planning ...
(Date:8/22/2017)... ... August 22, 2017 , ... GeBBS ... recently the availability of a new professional fee E/M leveling calculator tool. The ... to the healthcare industry. E/M coding is complex which supports the need for ...
(Date:8/22/2017)... (PRWEB) , ... August 22, 2017 , ... Five Star Glass is new to the ... repair and replacement of auto glass for most makes and models, in Grand Prairie, TX, ... USA. , They have been a family owned business for the past 40 years ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... 15, 2017   Mostyn Law and Gulf Coast Regional ... Texas . The Mostyn Law family has had ... That is why Mostyn Law is partnering with Gulf ... show its appreciation. Blood supplies are running low. Gulf ... of hospital needs in August. That is why the blood center ...
(Date:8/15/2017)... Inc. announced today that its fully owned USA ... York City Office in Yonkers, New York ... (TWO 2 ) homecare therapy. This new East Coast location has ... under the company,s DMEPOS accreditation for Home/Durable Medical Equipment Services. ... Advanced Oxygen Therapy Inc. New ...
(Date:8/8/2017)... Aug. 8, 2017  BioLineRx Ltd. (NASDAQ/TASE: BLRX), a ... reports its financial results for the second quarter ended ... the second quarter 2017 and to date: ... development programs for the Company,s lead project, BL-8040: ... study with BL-8040 as novel stem cell mobilization treatment ...
Breaking Medicine Technology: