Navigation Links
Steering stem cells to become 2 different building blocks for new blood vessels
Date:12/20/2012

Growing new blood vessels in the lab is a tough challenge, but a Johns Hopkins engineering team has solved a major stumbling block: how to prod stem cells to become two different types of tissue that are needed to build tiny networks of veins and arteries.

The team's solution is detailed in an article appearing in the January 2013 print edition of the journal Cardiovascular Research. The article also was published recently in the journal's online edition. The work is important because networks of new blood vessels, assembled in the lab for transplanting into patients, could be a boon to people whose circulatory systems have been damaged by heart disease, diabetes and other illnesses.

"That's our long-term goal: to give doctors a new tool to treat patients who have problems in the pipelines that carry blood through their bodies," said Sharon Gerecht, an assistant professor of chemical and biomolecular engineering who led the research team. "Finding out how to steer these stem cells into becoming critical building blocks to make these blood vessel networks is an important step."

In the new research paper, the Gerecht team focused on vascular smooth muscle cells, which are found within the walls of blood vessels. Two types have been identified: synthetic smooth muscle cells, which migrate through the surrounding tissue, continue to divide and help support the newly formed blood vessels; and contractile smooth muscles cells, which remain in place, stabilize the growth of new blood vessels and help them maintain proper blood pressure.

To produce these smooth muscle cells, Gerecht's lab has been experimenting with both National Institutes of Health-approved human embryonic stem cells and induced pluripotent stem cells. The induced pluripotent stem cells are adult cells that have been genetically reprogrammed to act like embryonic stem cells. Stem cells are used in this research because they possess the potential to tran
'/>"/>

Contact: Phil Sneiderman
prs@jhu.edu
443-287-9960
Johns Hopkins University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Kessler Foundations A.M. Barrett appointed to National Quality Forum Steering Committee
2. New drug prevents spread of human prostate cancer cells
3. Tiny hitchhikers attack cancer cells
4. To prevent leukemias dreaded return, go for the stem cells
5. Scientists identify major source of cells defense against oxidative stress
6. Therapy exploits addiction of leukemia cells
7. IBN discovers human neural stem cells with tumor targeting ability
8. Leukaemia cells have a remembrance of things past
9. Small molecular bodyguards kill HPV-infected cancer cells by protecting tumor-suppressor
10. Research yields new clues to how brain cancer cells migrate and invade
11. Presence of fetal cells in women lowers risk of breast cancer but raises risk of colon cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Steering stem cells to become 2 different building blocks for new blood vessels
(Date:7/5/2015)... (PRWEB) , ... July 06, 2015 , ... ... ancillary benefits market, is excited to announce the next generation of PrimeStar Individual ... Advantage plans to now include two network options—Maximum Allowable Charge (MAC) and usual, ...
(Date:7/5/2015)... , ... July 05, 2015 , ... Women's Excellence ... studio in Lake Orion. These classes are geared towards families that want their ... summer break. , The fitness class will take place TUESDAYS at 4:30pm. ...
(Date:7/5/2015)... , ... July 05, 2015 , ... Women’s Excellence ... college) at their Lake Orion location. The special consists of 2 months of unlimited ... Wellness, powered by Movestrong is located at 1410 South Lapeer Road in Lake Orion. ...
(Date:7/4/2015)... ... July 05, 2015 , ... Dating a real millionaire online can be more ... dating service and strives to remove the worries from meeting partners. Recently, the ... app of 2015 and readers have responded with excitement. , “There's quite ...
(Date:7/4/2015)... ... July 04, 2015 , ... Chronic Neck Pain. Neck ... sufferers have pain located in the neck. Another 19% suffer from head, migraine, or ... literature suggests that 45% of American workers must deal with neck pain. ...
Breaking Medicine News(10 mins):Health News:Security Life Insurance Company of America Launches the Next Generation of PrimeStar Individual Dental Insurance Plans 2Health News:MillionaireMatchapp.com Publishes the Best Millionaire Dating App and Official Dating Site Reviews 2015 2Health News:New Advancement in Treatment of Chronic Neck Pain 2Health News:New Advancement in Treatment of Chronic Neck Pain 3
... available in the December issue of Hepatology , ... of Liver Diseases, have uncovered limitations in screening for ... The first study found that, if given the choice ... surveillance over the possibility of non-screening, therefore making a ...
... (Boston) Stephen Hammond, MD, a fourth-year resident in ... (BMC), recently received the highly coveted Resident Leadership ... Pathology (ASCP) for demonstrating leadership and promoting ASCP ... with the laboratory team led by Dr. Martin ...
... Less than one-quarter (23%) of children with HIV/AIDS ... report released by the World Health Organization (WHO) on ... Although treatment coverage for adults has been steadily climbing ... need, coverage for children is lagging far behind, highlighted ...
... Biomedical engineer Marissa Nichole Rylander , associate professor ... Tech Wake Forest University School of Biomedical Engineering ... of the 2012 Y.C. Fung Young Investigator Award. ... are committed to pursuing research in the field of ...
... , THURSDAY, Dec. 1 (HealthDay News) -- The overlap of ... it a challenge to stay healthy as you go to parties ... shot is important, but other precautions can also reduce your risk ... a Ryerson University news release. Here are some tips for ...
... WASHINGTON, DC, November 28, 2011 Not only are working ... experience is more negative as well, according to a new ... Review . "Gender differences in multitasking are not ... Shira Offer, the lead author of the study and an ...
Cached Medicine News:Health News:Studies of patients with cirrhosis uncover limitations in liver cancer screening 2Health News:Children with HIV/AIDS falling through the cracks of treatment scale-up efforts 2Health News:Virginia Tech's Rylander wins national biomedical engineering award 2Health News:Virginia Tech's Rylander wins national biomedical engineering award 3Health News:How to Stay Flu-Free for the Holidays 2Health News:Study: Working moms multitask more and have worse time doing so than dads 2Health News:Study: Working moms multitask more and have worse time doing so than dads 3
(Date:7/6/2015)... , July 6, 2015 ... Cellvizio®, the multidisciplinary confocal laser endomicroscopy platform, announced ... Japan,s Ministry of Health, Labor and ... Endomicroscopy solution, the AQ-Flex 19 miniprobe.   ... -Flex™ 19 miniprobe is comprised of a fiber-optic ...
(Date:7/6/2015)... June 29, 2015 Research ... the "Pharmaceutical Packaging Market in North America 2015-2019" ... packaging market in North America ... period 2014-2019. International regulations regarding safe ... manufacturers, which in turn fuels adoption of sustainable packaging. ...
(Date:7/6/2015)... Research and Markets( http://www.researchandmarkets.com/research/45v9b3/urinary_slings ... Slings Market in the US 2015-2019" report to ... Slings market in the US to grow at a ... This report covers the present scenario and the growth ... for the period 2015-2019. To calculate the market size, ...
Breaking Medicine Technology:Mauna Kea Technologies Receives Regulatory Approval for the AQ-Flex 19 Miniprobe in Japan 2Mauna Kea Technologies Receives Regulatory Approval for the AQ-Flex 19 Miniprobe in Japan 3North American Pharmaceutical Packaging Market 2015-2019 with Amcor, Bemis Healthcare Packaging, MeadWestvaco, Owens-Illinois & West Pharmaceutical Services Dominating 2North American Pharmaceutical Packaging Market 2015-2019 with Amcor, Bemis Healthcare Packaging, MeadWestvaco, Owens-Illinois & West Pharmaceutical Services Dominating 3United States Urinary Slings Market 2015-2019 - Vaginal Slings (TVT, TOT, and Single-incision) & Male Slings (Artificial Urinary Sphincters) 2
... CARY, N.C. , June 30 ... pharmaceutical company focused on acquiring, developing and commercializing significant ... announced the resignation of David Price , Executive ... the Company to accept a chief financial officer position ...
... SANTA ANA, Calif. , June 29 At 2 pm today, a ... where Malinda Traudt gets her medical marijuana.  But, the Court of Appeal stepped in ... (Photo: http://photos.prnewswire.com/prnh/20100518/LA07170 ) , ... (Photo: http://www.newscom.com/cgi-bin/prnh/20100518/LA07170 ) , , , ...
Cached Medicine Technology:Cornerstone Therapeutics Announces Management Change 2Cornerstone Therapeutics Announces Management Change 3Appellate Court Sides With Terminally-Ill Medical Marijuana Patient 2Appellate Court Sides With Terminally-Ill Medical Marijuana Patient 3
... assays can be used to screen ... which are associated with various systemic ... erythematosus (Lupus), Sjgren's syndrome, mixed connective ... polymyositis, dermatomyositis, and Raynaud's phenomenon. They ...
... assays can be used to screen ... which are associated with various systemic ... erythematosus (Lupus), Sjgren's syndrome, mixed connective ... polymyositis, dermatomyositis, and Raynaud's phenomenon. They ...
... The ANA and ENA assays ... patients negative for antinuclear antibodies, which ... diseases such as Systemic lupus erythematosus ... disease, progressive systemic sclerosis, scleroderma, polymyositis, ...
... ENA assays can be used to ... antibodies, which are associated with various ... lupus erythematosus (Lupus), Sjgren's syndrome, mixed ... scleroderma, polymyositis, dermatomyositis, and Raynaud's phenomenon. ...
Medicine Products: