Navigation Links
Steady Weight Gain Boosts Late-Life Breast Cancer Risk
Date:4/20/2010

Average-sized woman doubles her odds by adding 30 pounds over 30 years, researchers say

TUESDAY, April 20 (HealthDay News) -- Women who pack on the pounds over their lifetime steadily increase their risk for postmenopausal breast cancer, compared with women who maintain their weight, a new study finds.

Earlier studies have linked excess weight with an increased risk for breast cancer in postmenopausal women, but this is one of the few studies that traces the risk as a function of weight gain over time.

"Among women who had never used postmenopausal hormone therapy, those who had a body-mass index (BMI) gain between age 20 and 50 had a doubling of breast cancer risk," said lead researcher Laura Sue, a cancer research fellow at the U.S. National Cancer Institute.

Sue was expected to present the findings Tuesday at the American Association for Cancer Research's annual meeting, in Washington D.C.

For the study, Sue's team collected data on more than 72,000 women who took part in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. When the study began, the women were between 55 and 74 years old. Among these women, 3,677 had developed a postmenopausal breast cancer.

The researchers looked only at women who had had breast cancer and had never taken hormone replacement therapy to reduce menopausal symptoms. Hormone therapy can boost the risk for developing breast cancer, so by looking at women who had never taken the therapy, the researchers were able to better isolate weight as an individual risk factor.

Compared with women who maintained about the same weight at 50 as they had at age 20, women who gained about 30 pounds over the years increased their risk for breast cancer twofold, the study found.

Among the women in the study, almost 57 percent had increased their BMI by five kilograms per meter squared (kg/m2) over 30 years. That's akin to a women 5 feet 4 inches tall putting on about 30 pounds, Sue said.

An increase in BMI of 5 kg/m2 or more over 30 years increased the risk of developing postmenopausal breast cancer by 88 percent, compared with women whose BMI remained stable over the same period.

Among women whose BMI increased 5 kg/m2 or more from the age of 50 onwards, their risk for breast cancer increased 56 percent, compared with women whose BMI remained the same. That means that jumps in weight before and after age 50 boost a woman's odds for postmenopausal breast cancer, the researchers noted.

The increased risk for breast cancer was tied to the weight gain itself, not to becoming obese, Sue added.

The rise in risk may be due to an increase in the production of estrogen in the body's excess fat cells, which in turn may increase the number of cells produced in the breasts, upping the risk for cancer, Sue said.

The bottom line: "We believe healthy BMI maintenance throughout adulthood is important in terms of breast cancer risk," she said.

More information

For more information on breast cancer, visit the American Cancer Society.



SOURCES: Laura Sue, M.P.H., cancer research fellow, U.S. National Cancer Institute; April 20, 2010, presentation, American Association for Cancer Research annual meeting, Washington D.C.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New figures on cancer in Europe show a steady decline in mortality but big variations
2. Gilbert Hospital Forecasts Steady 2010
3. Duffy & Duffy Continues Steady Growth with Addition of Two Seasoned Medical Malpractice Attorneys
4. Weight Watchers Declares Quarterly Dividend
5. Fat-Burning Chemical Points to New Weight-Loss Drug
6. Diabetes Drug Helps Dieting Teens Lose Weight
7. SILS -- A New Houston Weight Loss Surgery -- Single Incision Laparoscopic Surgery
8. Most parents dont realize their 4 or 5 year-olds are overweight or obese
9. Over 70 and Overweight May Add Years to Life
10. A gimmick-free weight-loss pill in the works
11. Pregnant women who are overweight put their infants at risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader ... been awarded a contract by the Center for Medicare and Medicaid Services (CMS). ... the enterprise use of Agile methodologies in a consistent and high value manner ...
(Date:10/12/2017)... Del. (PRWEB) , ... October 12, 2017 , ... ... and advisory services for healthcare compliance program management, will showcase a range of ... National Association for Assisted Living (NCAL) Convention and Expo to be held October ...
(Date:10/12/2017)... ... 2017 , ... The company has developed a suite of ... authorities worldwide. From Children’s to Adults 50+, every formula has been developed by ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, Preservative ...
(Date:10/12/2017)... ... , ... Asante, a nationally recognized health system in southern ... home health joint venture through an agreement, effective October 1, 2017, to create ... health company with Asante, delivering clinically integrated care, for the past eight years. ...
(Date:10/12/2017)... Malvern, PA (PRWEB) , ... October 12, 2017 , ... ... is the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best ... New York City on October 11, 2017. , The annual award competition recognizes editorial ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... 22, 2017 AVACEN Medical (AVACEN) announced that ... successfully helping those with the widespread pain associated with ... Amanda in Essex, England commented, ... hair, experiencing no sleep at all, tremendous pain, with ... cannot recommend [the AVACEN 100] enough, how this has ...
(Date:9/18/2017)... ALLENTOWN , Pa. and KALAMAZOO, Mich. ... Allentown, Penn. , and OptiMed Specialty Pharmacy ... a business partnership to offer a strategic hub service ... PMD Healthcare,s highly sought-after personal spirometer, Spiro PD 2.0, ... A spirometer is a medical device used ...
(Date:9/12/2017)... NEW YORK , Sept. 12, 2017   EcoVadis , ... supply chains, has published the first annual edition of its Global CSR ... than 20,400 companies evaluated by EcoVadis, based on Scorecard Ratings that analyzed ... ... & Performance Index ...
Breaking Medicine Technology: