Navigation Links
Statins show promise for blood clot prevention
Date:10/27/2008

Statins, the class of drugs commonly used for lowering cholesterol, are now showing promise at preventing deep vein thrombosis (DVT) or blood clots, an affliction that occurs in nearly 2 million Americans each year. New research presented at CHEST 2008, the 74th annual international scientific assembly of the American College of Chest Physicians (ACCP), suggests that the use of statins may be associated with a significant reduction in the occurrence of venous thromboembolism (VTE), a condition that includes DVT and pulmonary embolism, in patients with solid organ tumors, including breast, lung, and colon cancers.

"The results of our research are interesting and thought provoking," said study author Danai Khemasuwan, MD, Albert Einstein Medical Center, Philadelphia, PA. "We hope that our research alerts the scientific community to the potential of statins in reducing VTE."

Dr. Khemasuwan and his colleagues from Albert Einstein Medical Center evaluated the influence of statins use on the incidence of VTE by reviewing 740 consecutive patients admitted to the hospital between October 2004 and September 2007 with a diagnosis of breast, lung, colon, prostate, stomach, esophagus, pancreas, ovary, kidney, or brain cancer. The occurrence of VTE, risk factors for VTE, and use of statins were recorded. Patients who either used statins for less than 2 months or who never used statins were allocated to the control group.

The mean age of the entire study population was 65 years, 52 percent of subjects were women, and 76 percent were African-American. A total of 26 percent of patients received statins, and the overall incidence of VTE was 18 percent. The analysis revealed that patients receiving statins were significantly less likely to develop VTE than the control group, with 8 percent of patients receiving statins developing VTE compared with 21 percent in the control group. A logistical regression analysis yielded the same results irrespective of smoking, documented metastatic disease, current use of chemotherapy, immobilization, and use of aspirin.

Although the authors could not draw conclusions about the cause and effect relationship between statins and VTE, Dr. Khemasuwan feels the data are promising. "If the results of our study are confirmed in a prospective randomized, controlled trial, this could have very significant implications for the medical community."

"Recent studies have examined the use of statins for the prevention of lung disease, stroke, and other neurologic disorders," said James A. L. Mathers, Jr., MD, FCCP, President of the American College of Chest Physicians. "The results of this study are promising and suggest a potential role for statins in the prevention of thromboembolism."


'/>"/>

Contact: Jennifer Stawarz
jstawarz@chestnet.org
847-498-8306
American College of Chest Physicians
Source:Eurekalert

Related medicine news :

1. Statins Show Promise for Blood Clot Prevention
2. Statins Help Obese People After Bypass Surgery
3. Research Shows Why Statins Dont Work for Everyone
4. Statins May Help Older Women Control Irregular Heartbeat
5. When statins arent enough: New trial drug points to better management of coronary heart disease
6. iGuard.org Presents New Data on Statins at FDA Workshop Demonstrating How Patient-Reported Information Can Enhance Drug Safety Knowledge
7. Women are treated less frequently than men with statins, aspirin and beta-blockers
8. Cholesterol-Lowering Statins Tied to Tendon Woes
9. Tendon complications, though rare, linked to statins
10. New Gene-Based Therapy an Alternative to Vytorin and Statins in Heart Disease Prevention and Treatment
11. Latest Study Says Statins Dont Slow Alzheimers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills ... specialty vendors and unique items from across the nation, this holiday-themed event will raise ... offered by the VNA. The boutique will be open Saturday, November 4 (10:00 ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
(Date:10/12/2017)... ... ... Planet Fitness, one of the largest and fastest growing franchisors and operators ... location in Covington, LA at 401 N. U.S. Highway 190, in January of 2018. ... in the Holiday Square shopping center. Its location allows it to serve both Covington ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... system that we intend to develop to enable prevention of a major side ... severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss is FDA ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned ... Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. OnSite Wellness ... on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at the Henry ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... Sept. 25, 2017   Montrium , an ... solutions, today—from the IQPC Trial Master Files & ... NL)—announced that EastHORN Clinical Services has selected ... and TMF management. EastHORN, a leading European contract ... to increase transparency to enable greater collaboration with ...
(Date:9/22/2017)... -- AVACEN Medical (AVACEN) announced that its CE-Marked AVACEN ... with the widespread pain associated with fibromyalgia in the ... Essex, England commented, "I had difficulty ... sleep at all, tremendous pain, with every movement sending ... AVACEN 100] enough, how this has and is helping ...
(Date:9/18/2017)... Sept. 18, 2017 EpiVax, Inc. ... bioinformatics and immune engineering, today announced a ... A (H7N9) vaccine. ... seasonal influenza and presents a challenge for ... exposure to be effective. Using state-of-the-art bioinformatics and ...
Breaking Medicine Technology: