Navigation Links
Statins may exert influence on prostate cancer growth by reducing inflammation
Date:4/25/2009

DURHAM, N.C. Cholesterol-lowering drugs called statins may reduce inflammation in prostate tumors, possibly hindering cancer growth, according to a study led by investigators in the Duke Prostate Center.

"Previous studies have shown that men taking statins seem to have a lower incidence of advanced prostate cancer, but the mechanisms by which statins might be affecting the prostate remained largely unknown," said Lionel Baez, M.D., a researcher in the Duke Prostate Center and lead investigator on this study. "We looked at tumor samples and found that men who were on statins had a 72 percent reduction in risk for tumor inflammation, and we believe this might play a role in the connection between prostate cancer and statin use."

The researchers presented their finding at the American Urological Association's annual meeting on April 26, 2009, and the study was selected to be part of the meeting's press program on April 27, 2009. The study was funded by the United States Department of Defense and the American Urological Association Foundation.

The researchers looked at pathological information from the tumors of 254 men who underwent radical prostatectomy or surgery to remove the entire prostate as a treatment for prostate cancer at the Durham Veterans Affairs Medical Center between 1993 and 2004. The tissue was graded by a pathologist for inflammation on a scale of 0 to 2: 0 for no inflammation, 1 for mild inflammation (less than 10 percent of the tumor) and 2 for marked inflammation (greater than 10 percent of the tumor).

"This finding provides a potential mechanism of action for statins' effects on prostate cancer biology," Baez said.

Other Duke Prostate Center research has found that inflammation in tumors is associated with recurrent prostate cancer, so these two findings, taken together, provide more impetus for considering the use of statins to possibly control or prevent prostate cancer, Baez said.

"
'/>"/>

Contact: Lauren Shaftel Williams
lauren.shaftel@duke.edu
919-684-4966
Duke University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Many Who Should Use Statins Dont
2. Statins May Help Before Artery-Opening Surgery
3. Study Finds Millions More May Benefit From Statins
4. 6.5 million more patients might benefit from statins to prevent heart attacks, strokes
5. Statins lower stroke severity, improve recovery
6. Dallas Scientists Discover Statins May Falsely Indicate Thyroid Problems
7. Statins Pay Off on a Health-Policy Level, UCSF Study Finds
8. Not Many U.S. Kids Need Statins
9. Taking Statins Faithfully Lengthens Life
10. Statins Dont Cut Cancer Risk
11. Got High Cholesterol? Statins Are Not the Only Answer, Says Natural Solutions Magazine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... (PRWEB) August 22, 2014 With the ... Stores (NACDS) Total Store Expo - which will be ... published a pro-pharmacy op-ed in its online opinion section, ... enlist pharmacists ” is co-authored by Steven C. Anderson, ... Malloy, PharmD, dean of the MCPHS University School of ...
(Date:8/22/2014)... Jose, CA (PRWEB) August 22, 2014 ... now offering a new teeth whitening technique. Air polishing ... regular cleaning appointments. , Dark teeth can be caused ... two categories: external stains and internal stains. External stains ... stains can be caused by certain medications, such as ...
(Date:8/22/2014)... Millennium Treatment Group has recently noticed an increase in ... drug use among teenagers. The treatment facility aims to help ... to minimize drug abuse. , America is currently seeing some ... history. According to the National Institute of Drug Abuse ... or older—or 9.2 percent of the population—had used an illicit ...
(Date:8/22/2014)... 2014 Recently, iFitDress.com, a well-known wedding ... of discounted wedding gowns . In addition to ... these new products are provided with low shipping fees. ... to unveil the new wedding gowns. In our online ... for ladies to choose from. What’s more, all of ...
(Date:8/22/2014)... August 22, 2014 The regional economy ... Indiana is on the grow again. The ... by summer 2016 to boost production of the popular ... Toyota Indiana’s overall investment to $4 billion. This step ... while providing additional flexibility to adjust its product mix ...
Breaking Medicine News(10 mins):Health News:The Boston Globe Publishes Value of Pharmacy Op-ed as NACDS Total Store Expo Begins 2Health News:The Boston Globe Publishes Value of Pharmacy Op-ed as NACDS Total Store Expo Begins 3Health News:Japantown Dental Introduces Air Polishing 2Health News:Millennium Treatment Group Sees Increase in Marijuana Use Among Youth 2Health News:Discounted Wedding Gowns For Sale At Leading Online Shop iFitDress.com 2Health News:Toyota Indiana Adding 300 Jobs to Build More Highlanders 2
... 28 WellSpring Pharmaceutical,Corporation, a growing North American-based ... named Chief Operating Officer.,Formerly, Ms. Shusko held the ... in early 2000. In her new role as ... her areas of oversight,to operations with an initial ...
... NQF-endorsed measures can improve quality of care for ... the,importance of quality healthcare for mothers and newborns ... measure and thereby,improve care received by mothers and ... discharge. Consensus standards improve quality,of care by standardizing ...
... who received blood that was 29 days or older faced ... Hospital patients who receive a transfusion of stored blood that ... developing one or more serious infections compared to those who ... pointed out that current U.S. regulations set the upper limit ...
... Device Designed to Minimize Discomfort and Pain Following ... a world-leading,manufacturer of ostomy and wound care products, ... a new post-operative ostomy,device. The product offers clinicians ... manage abdominal pain in the days and weeks ...
... Today, PARI Respiratory,Equipment presented a comparative study ... in-vitro performance and delivery,efficiency of budesonide inhalation ... study show that the LC Sprint,Reusable Nebulizer ... average,of 4.9 minutes, and had the highest ...
... of Portland,Oregon is pleased to announce its partnership ... a new company, Wellsource Health Solutions.,This joint venture ... provide,full-service solutions that meet the specific needs of ... Customers and their,participants will benefit from a new ...
Cached Medicine News:Health News:WellSpring Pharmaceutical Corp. Names Wendy Shusko as New Chief Operating Officer 2Health News:National Quality Forum Endorses National Consensus Standards for Perinatal Care 2Health News:National Quality Forum Endorses National Consensus Standards for Perinatal Care 3Health News:Older Blood Boosts Chances of Infection in Transfusion Patients 2Health News:Older Blood Boosts Chances of Infection in Transfusion Patients 3Health News:ConvaTec Launches SUR-FIT Natura(R) Low-Pressure Adaptor 2Health News:ConvaTec Launches SUR-FIT Natura(R) Low-Pressure Adaptor 3Health News:PARI Respiratory Releases Results of Study Comparing Nebulizers Delivering Budesonide at CHEST 2008 2Health News:Wellsource Partners With Health Solutions Ltd. to Form Best-in-Class Health and Wellness Solutions for Its Clients. 2Health News:Wellsource Partners With Health Solutions Ltd. to Form Best-in-Class Health and Wellness Solutions for Its Clients. 3
(Date:8/22/2014)... HILL, N.C. , Aug. 22, 2014  Medical ... organizations and thought leaders in the healthcare sector. As ... evolve, the iPad is changing how Medical Science Liaisons ... MSLs are using the tablet to not ... but also to better coordinate thought leader interactions across ...
(Date:8/22/2014)... , August 22, 2014 ... http://www.researchandmarkets.com/research/x34qgv/global_laboratory ) has announced the addition of ...  report to their offering.       ... an essential instrument for any modern science ... weighing of materials. It can be broadly ...
(Date:8/22/2014)... , August 22, 2014 ... has announced the addition of the  "Global ... their offering.       (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... with a sterile environment in a healthcare ... is equipped with technically advanced equipment, which ...
Breaking Medicine Technology:iPads Enhancing Medical Science Liaison Interactions with Thought Leaders, New Study Shows 2Global Laboratory Electronic Balance Market 2014-2018: Key Vendors are A&D Company, Mettler-Toledo, Sartorius and Thermo Fisher 2Global Operating Room Equipment Market 2014-2018: Key Vendors are Getinge, STERIS, Stykron and TRUMPF Medical Systems 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: