Navigation Links
Statins could ease coughing in lung disease patients, study finds
Date:3/24/2014

Common cholesterol-lowering drugs could provide relief to patients suffering from a chronic lung disease, a study has shown.

The drugs known as statins were found to help alleviate the chronic coughing associated with the disease for some patients.

Statins are commonly prescribed for people at risk of heart attack because they can reduce cholesterol levels, but scientists are increasingly finding that they also have anti-inflammatory effects.

Researchers at the University of Edinburgh have shown the therapeutic potential of statins to treat patients with an inflammatory lung condition known as bronchiectasis.

Bronchiectasis is a disabling disease affecting one in 1000 British adults that is associated with a vicious cycle of bacterial infection and inflammation in the lungs and airways. It can be life-threatening and it leaves patients with daily symptoms that include chronic coughing, excessive phlegm production and repeated chest infections.

The team found that a daily high dose of statins over six months led to significant improvement in coughing symptoms for 12 out of the 30 patients treated in the study.

After six months of taking statins, patients could better tolerate gentle exercise and walk further than they could before treatment. They also had fewer flare ups of disease and less inflammation in their airways.

Six patients stopped taking the statins before the end of the study because of side effects such as headaches. However, there were no serious side effects from the treatment.

The findings suggest that statins could offer an alternative to long-term antibiotic treatment, which raises patients' risk of infection from antibiotic resistant strains of bacteria such as MRSA or C. difficile.

For most patients the causes of bronchiectasis are not known but it has been linked to serious lung infections in childhood, such as whooping cough or pneumonia, which damage the airways.

Dr Pallavi Mandal, a Clinical Research Fellow at the University of Edinburgh who led the study, said: "There are few effective treatments for bronchiectasis so these are encouraging findings. Larger studies are now needed to find out whether statins could be useful as a long-term treatment option for patients with this disease."


'/>"/>

Contact: Jen Middleton
jen.middleton@ed.ac.uk
44-131-650-6514
University of Edinburgh
Source:Eurekalert

Related medicine news :

1. High potency statins linked to better outcome following a heart attack
2. Could statins be used to fight a deadly viral infection?
3. As Lipitor Lawsuits Mount, Bernstein Liebhard LLP Notes Publication of New Study with Possible Explanation for Link between Statins and Diabetes
4. Cleveland Clinic research: Most statin-intolerant patients can eventually tolerate statins
5. High dose statins prevent dementia
6. Statins reduce CV events in CAD patients with very low LDL-C
7. Statins prevent cataracts
8. Specialized treatment helps cholesterol patients who suffer side effects from statins
9. Could Statins Raise Diabetes Risk?
10. Statins May Hamper Workout Results
11. Zocor Side Effects Update: Bernstein Liebhard LLP Comments on New Study Linking Kidney Problems to High Doses of Zocor, Other Statins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/21/2017)... ... September 21, 2017 , ... Promotional Communication:, Keeping Up with ... In the competitive world of drug and device marketing and promotion, drug and ... rules. , The FDA has issued two draft guidances that are the closest ...
(Date:9/21/2017)... ... 21, 2017 , ... Innovatum will demonstrate capabilities of fully ... Conference 2017 in Chicago, IL on October 17-19, 2017. This unique development addresses ... patient safety. , Microscan , a global technology leader in barcoding, ...
(Date:9/21/2017)... ... , ... FlipBelt, the fitness brand that specializes in problem solving fitness accessories, ... with the launch of their FlipBelt Crops. , The new fitness bottoms feature an ... while at the gym, on the trail, or on-the-go. , “We always thought the ...
(Date:9/20/2017)... ... September 20, 2017 , ... FirstAlign ( http://www.firstalign.com ), combines ... Artificial Intelligence (AI) thinking, announced today the launch of its revamped web presence. ... information that offers a more comprehensive understanding of the organization’s business and machine ...
(Date:9/20/2017)... Massachusetts (PRWEB) , ... September ... ... , a software company specializing in medical device compliance and commercialization, has ... in risk management activities. , FDA is more adamant than ever about ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... , Sept. 12, 2017  Consumer reviews on the independent review ... as the number one company for hearing aids, ranking it higher ... other brands. ... Named #1 by Consumers For Hearing Aids ... Embrace Hearing is an online store that provides high performance, state-of-the-art, ...
(Date:9/9/2017)... , Sept. 8, 2017 Dealmed Medical Supplies, ... supplier of medical equipment, supplies, drugs, vaccines, and specialty ... entered into an agreement to acquire Vantage Medical Supplies, ... in Holtsville, New York . ... supplying new and emerging medical practices, will operate under ...
(Date:9/7/2017)... nearly two decades, New Life Agency has been committed to providing the ... Life Agency announces a powerful three-way partnership designed to deliver substantial savings ... ... http://www.schrafts2.com/ (PRNewsfoto/PharmaCareCard) ... http://pharmacarecard.com/ (PRNewsfoto/PharmaCareCard) ...
Breaking Medicine Technology: