Navigation Links
Statins OK for Patients With Abnormal Liver Function: Study
Date:11/24/2010

TUESDAY, Nov. 23 (HealthDay News) -- Long-term use of cholesterol-lowering statins does not increase the risk of liver disease in patients with abnormal liver function, and can actually improve liver function, according to a new study that challenges widespread belief.

The researchers also pointed out that this study is the first to show that statins provide a substantially greater cardiovascular benefit in patients with abnormal liver function than in those with normal liver function.

The study, published in the Nov. 24 online edition of The Lancet, included 437 patients with moderately abnormal liver tests believed to have non-alcoholic fatty liver disease. Statins were given to 227 patients, while the other 210 (the control group) received no treatment.

After three years of follow-up, the patients taking statins did not have a higher rate of liver problems than those in the control group. In addition, levels of alanine aminotransferase (ALT) -- a biomarker of liver problems -- decreased or normalized in the patients taking statins but worsened in the control group.

The investigators also found that patients with abnormal liver tests who took statins had a 39 percent to 68 percent reduced risk of cardiovascular events such as heart attack and stroke.

"The risk-to-benefit ratio of long-term statin treatment (mainly with atorvastatin in this study) favors statin administration even for patients with moderately abnormal liver tests," Vasilis Athyros, of the Hippokration University Hospital in Thessaloniki, Greece, Dr. Dimitri Mikhailidis, of University College London in the United Kingdom, and colleagues concluded.

More information

The American Liver Foundation explains how to care for your liver.

-- Robert Preidt

SOURCE: The Lancet, news release, Nov. 23, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Statins Dont Reduce Colon Cancer Risk, Study Finds
2. Statins did not reduce colorectal cancer in WHI analysis
3. Statins dont prove useful for general pediatric lupus population
4. Aspirin, Statins May Reduce Problems After Heart Surgery
5. Statins May Guard Against Rheumatoid Arthritis
6. Study Suggests Statins Could Help Some With Normal Cholesterol
7. Statins, Painkillers May Upset PSA Test Results
8. Some on Statins May Not Need Boost in Good Cholesterol
9. Statins May Not Be as Helpful for Those Without Heart Disease
10. Statins May Lower Rates of Prostate Cancer Recurrence
11. Statins associated with lower cancer recurrence following prostatectomy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Statins OK for Patients With Abnormal Liver Function: Study
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, ... lowdown on sciatica in a new episode of "Success Files," which is an ... and innovation and investigates each subject in-depth with passion and integrity. , Sciatica ...
(Date:10/13/2017)... ... ... “The Journey: From the Mountains to the Mission Field”: the story of ... Philippines. “The Journey: From the Mountains to the Mission Field” is the creation of ... taught all ages and currently teaches a class of ladies at her church, which ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... for healthcare compliance program management, will showcase a range of technology and learning ... Assisted Living (NCAL) Convention and Expo to be held October 14–18, 2017 at ...
(Date:10/12/2017)... ... ... Planet Fitness, one of the largest and fastest growing franchisors and operators ... location in Covington, LA at 401 N. U.S. Highway 190, in January of 2018. ... in the Holiday Square shopping center. Its location allows it to serve both Covington ...
(Date:10/12/2017)... ... , ... IsoComforter, Inc. ( https://isocomforter.com ), one of the Nation’s ... design of the shoulder pad. The shoulder pad provides optimal support and full ... while using cold therapy. By utilizing ice and water that is circulated from an ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... 2017  True Health, a leader in integrated ... during National Breast Cancer Awareness month to educate ... Research recently published ... more than 10 million American women are at ... or BRCA2 and have not had testing. These mutations ...
(Date:10/5/2017)... Ill. , Oct. 5, 2017  In ... Association of Oral and Maxillofacial Surgeons (AAOMS) released ... opioids – to be used as a first-line ... pain. Recognizing ... the AAOMS White Paper "Opioid Prescribing: Acute and ...
(Date:10/2/2017)... -- Eli Lilly and Company (NYSE: LLY ) ... of 2017 on Tuesday, October 24, 2017. Lilly will ... the investment community and media to further detail the ... begin at 9 a.m. Eastern time. Investors, media and ... the conference call through a link that will be ...
Breaking Medicine Technology: