Navigation Links
Statins Might Stave Off Alzheimer's
Date:6/30/2009

In animal study, drug blocks cell death characteristic of the disease

TUESDAY, June 30 (HealthDay News) -- Treatment with a cholesterol-lowering drug might protect against Alzheimer's disease, new research suggests.

Scientists have long known that nerve cells in people with Alzheimer's die prematurely because they are strongly overstimulated, a process called excitotoxicity.

Theorizing that the cholesterol drug lovastatin might ward off cell death, researchers at the University of Groningen, The Netherlands, conducted animal experiments in which they administered lovastatin (Altoprev, Mevacor) to overstimulated nerve cells. Lovastatin is a first-generation member of a class of drugs, statins, that has revolutionized the treatment of high cholesterol.

Lovastatin did indeed prevent cell death and, just as important, blocked the loss of memory that accompanies excitotoxicity, according to the lead scientist on the project, Amalia Dolga. Earlier, Dolga had shown that statins seem to stimulate the protective capacity of tumor necrosis factor, a key player in the brain's immune response. In addition, some researchers have speculated that high cholesterol might be a risk factor for Alzheimer's, suggesting that lowering cholesterol could be beneficial.

The findings are in the June issue of the Journal of Alzheimer's Disease.

Alzheimer's disease affects more than 5 million people in the United States. The degenerative disease attacks brain cells and ruins memory and thinking. It is the leading cause of dementia and the seventh-leading cause of death in the United States, according to the Alzheimer's Association.

No cure has been found, but treatments have been shown to improve a person's quality of life.

More information

The Alzheimer's Association has more on Alzheimer's disease.



-- Peter West



SOURCE: IOS Press, news release, June 22, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Statins can protect against Alzheimers disease, according to new study
2. Statins May Not Protect Against Pneumonia
3. Statins dont lower risk of pneumonia in elderly
4. A Substitute for Those Who Cant Take Statins?
5. Statins Can Help Prevent Second Stroke
6. Statins alter prostate cancer patients PSA levels
7. Statins Guard Against Prostate Cancer
8. Statins may exert influence on prostate cancer growth by reducing inflammation
9. Many Who Should Use Statins Dont
10. Statins May Help Before Artery-Opening Surgery
11. Study Finds Millions More May Benefit From Statins
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Statins Might Stave Off Alzheimer's
(Date:3/29/2017)... ... , ... ARI Network Services, Inc. (NASDAQ: ARIS) announced today that Rhino Ag ... network of more than 650 U.S.-based dealers. Rhino, a member of the Alamo Group, ... mowers and cutters, rear blades, post hole diggers, pasture renovators, tillers, disc mowers and ...
(Date:3/29/2017)... ... March 29, 2017 , ... The Professional Squash Association, the ... New York City-based sports and entertainment marketing firm Leverage Agency as its exclusive ... the Professional Squash Association (PSA), which includes first-time ever title sponsorship, naming rights, ...
(Date:3/29/2017)... ... 30, 2017 , ... Grass pollen is the main cause of hay fever in the United ... for grass pollen runs from May to July each year; with the worst time for ... HayMax™ allergen barrier balms ( http://www.haymax.us ) provide an effective defense against grass pollen; they ...
(Date:3/29/2017)... ... ... Youth Futures International (YFI) premiered its Serve, Learn, & Empower program in ... who have participated in the program every summer. The 2017 Serve, Learn, & ... enrollment. Visit http://www.ghana.yfiexperience.org to learn more. , “I have sent my ...
(Date:3/29/2017)... , ... March 30, 2017 , ... Sports Brand EXOUS ... brace, which retails normally at $29.97; for the remaining days of March, the price ... been reduced to a special price of just $10 (regular retail price $19.97). , ...
Breaking Medicine News(10 mins):
(Date:3/30/2017)... 30, 2017  Lannett Company, Inc. (NYSE: ... a $25 million payment against its existing revolving credit ... with the $75 million payment we made earlier this ... in annualized cash interest expense, at current rates" said ... "Our business is solid and we continue to generate ...
(Date:3/30/2017)... Revenue Prospects by Product Type (Metered Dose Inhalers, Dry ... Respiratory Inhalers - our new study reveals trends, R&D progress, ... If you are involved in this sector you must read this ... revenues streams to 2027, assessing data, trends, opportunities and business prospects ... Discover how ...
(Date:3/30/2017)... , March 30, 2017  Purcell Julie & Lefkowitz LLP, ... is investigating a potential breach of fiduciary duty claim involving ... SGYP ). If you are a ... information regarding this investigation, free of charge, please visit us ... ...
Breaking Medicine Technology: