Navigation Links
Statins May Lower Rates of Prostate Cancer Recurrence
Date:6/29/2010

By Randy Dotinga
HealthDay Reporter

MONDAY, June 28 (HealthDay News) -- A new study suggests that men who take the cholesterol-lowering drugs known as statins are a third less likely to suffer from recurrences of prostate cancer.

But don't demand that your doctor prescribe a statin -- drugs such as Crestor, Lipitor and Zocor -- for you just yet.

The findings aren't firm enough for doctors to make a blanket recommendation about statin therapy for men who have had prostate cancer, said study senior author Dr. Stephen Freedland, an associate professor of urology and pathology at Duke University.

Another physician went further, saying the findings simply aren't convincing.

Some prior research has suggested that men who took the cholesterol-lowering drugs were less likely than other men to develop advanced prostate cancer and have it come back. But other studies haven't found such positive effects, so the jury is still out, said Dr. Nelson Neal Stone, a professor of urology and radiation oncology at Mount Sinai School of Medicine.

The goal of the new study was to see if statins might be helping those who had already had the disease.

The researchers examined the medical records of more than 1,300 men who'd had their prostates removed after being diagnosed with prostate cancer. Of those, 18 percent were taking a statin when they had the procedures.

The study results appear in the June 28 online issue of the journal Cancer.

After adjusting their statistics so they wouldn't be thrown off by factors such as high or low numbers or who were, say, obese or older, researchers found that those on statins were 30 percent less likely to suffer a recurrence of prostate cancer. More specifically, tumors recurred in 25 percent of those who didn't use statins and 16 percent of those who did.

The study doesn't prove a cause-and-effect relationship: The statins did not necessarily directly lower the risk of prostate cancer recurrence, the experts note. To confirm whether a drug actually reduces risk, researchers rely on studies -- unlike this one -- that randomly assign patients to certain treatments.

Stone added that the study has statistical problems that make its results questionable.

Still, men did better if they took higher doses of statins, Freedland said, suggesting that the drugs may have an effect. They may work by reducing inflammation that spurs tumor growth, he theorized.

Statins are among the most widely prescribed drugs in America, but they do come with risks. Patients may develop liver problems and muscle damage, although the likelihood of that is low, Freeland said.

And the drugs aren't as inexpensive as, say, aspirin. Statins can cost $5 a day or more, depending on dose, although some are much cheaper.

However, not every prostate cancer patient may need to take them, Freedland said. Tests at the time of surgery can estimate a man's risk of prostate cancer recurrence, and statins would be most appropriate for those at highest risk, he explained.

For now, Freedland doesn't recommend that prostate cancer patients start taking statins to prevent recurrence. However, "if you're already on a statin, I'd keep you on that statin," he said. "If you have a clear-cut indication, the benefits outweigh the risks."

More information

For more about prostate cancer, try the U.S. National Library of Medicine.

SOURCES: Stephen Freedland, M.D., associate professor, urology and pathology, Duke University, Durham, N.C.; Nelson Neal Stone, M.D., professor, urology and radiation oncology, Mount Sinai School of Medicine, New York City; June 28, 2010, Cancer, online


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Statins associated with lower cancer recurrence following prostatectomy
2. MSU team studies connection between statins, tendon ruptures
3. Too Many Stroke Patients Go Without Statins
4. Some statins have unintended effects and warrant closer monitoring, study finds
5. Statins decrease risk of clot-related diseases
6. Statins Wont Lower Colon Cancer Risk
7. Do Statins Lower Male Sex Drive?
8. Statins May Slow Progression of Multiple Sclerosis, New Study Finds
9. Statins may slow progression of multiple sclerosis, new study finds
10. Alternative to Statins Shows Promise
11. Statins May Benefit Prostate Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Statins May Lower Rates of Prostate Cancer Recurrence
(Date:2/10/2016)... PLAINSBORO, N.J. (PRWEB) , ... ... ... J. Hennessy Associates, Inc. , a full-service health care communications company offering ... integrated digital news resource for practitioners and specialists working in infectious diseases. ...
(Date:2/10/2016)... ... February 10, 2016 , ... As part of its ... in February 2016. Each webinar features a dynamic expert and thoughtful presentation to ... athletes, patients and facilities. Both events are free to attend, but registration ...
(Date:2/10/2016)... ... February 10, 2016 , ... Compliancy Group LLC ... of medical professionals throughout the country. The Guard was specifically designed to handle ... procedures, employee training, regulatory updates, and compliance coaching. , In addition to meeting ...
(Date:2/10/2016)... ... 2016 , ... 10 Best Water is excited to announce a ... owners that topped the list as a result of their commitment to offering clients ... was Tibet 5100, a top notch water company that specializes in providing the public ...
(Date:2/10/2016)... ... ... Ongoing news of the ravages of traumatic brain injury (TBI) among former ... takes a closer look at cases of TBI being managed by their members. The ... the aging population, and identifies the challenges associated with their care. , During the ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... 10, 2016 /PRNewswire/ - The President of New Venture ... release of an anti-radiation product from their Research ... in the treatment of cancer using radiation and ... assist in the healing of radiation burns, even ... protect only the healthy cells from radiation damage. ...
(Date:2/10/2016)... , Feb. 10, 2016  Silicon Biosystems ... and products that help uncover the biological complexities ... Biosciences Inc., a developer of innovative technologies for ... co-marketing partnership aimed at enabling translational researchers to ... a couple hundred tumor and normal cells in ...
(Date:2/10/2016)... Fla. , Feb. 9, 2016  Until recently, ... were surgery or liposuction. Thankfully, the FDA approved the ... them to death. Coolsculpting was originally approved in 2010 ... the thighs and now the chin. With this add-on ... Center can use a smaller applicator, the CoolMini, to ...
Breaking Medicine Technology: