Navigation Links
Statin Therapy Helps Diabetic Patients
Date:1/11/2008

British study finds cholesterol-lowering drugs reduce risk of major vascular events

FRIDAY, Jan. 11 (HealthDay News) -- Most people with diabetes should be considered for treatment with cholesterol-lowering statins.

That's the advice of the authors of a study in the Jan. 12 issue of The Lancet.

The British and Australian researchers found that statins reduced the risk of major vascular events in a wide range of people with diabetes, regardless of age, sex and other clinical characteristics, and irrespective of whether they already had cardiovascular disease.

Diabetes is associated with an increased risk of cardiovascular disease.

For the study, the researchers conducted a meta-analysis of 18,686 people with diabetes and 71,370 without diabetes who took part in 14 randomized trials that examined the use of statins to reduce levels of low-density lipoprotein (LDL), or "bad" cholesterol.

During a mean follow-up of 4.3 years, 3,247 of the people with diabetes experienced vascular events. Among people with diabetes, there was a 9 percent proportional reduction in all-cause death per mmol/L reduction in LDL cholesterol, which was similar to the 13 percent reduction noted in people without diabetes.

The study authors said they found a significant 20 percent proportional reduction in major vascular events per mmol/L reduction in LDL cholesterol in people with diabetes, a decline similar to that seen in people without diabetes.

"This meta-analysis shows convincingly that the proportional benefits of statin therapy on major vascular events were similar in a wide range of individuals with diabetes, including those with no previous history of vascular disease, and benefits were similar to those observed in people without diabetes," the researchers wrote.

"Most people with diabetes should now be considered for statin therapy, unless their risk is low (e.g., as in children) or statin therapy has been shown to be unsuitable for them (e.g., as in pregnancy)," they concluded.

Statins are among the most notable achievements of modern medicine, but "one must not forget the importance of lifestyle changes, such as cessation of smoking, healthy diet, and regular exercise," Bernard Cheung, a professor of clinical pharmacology at the University of Birmingham in the United Kingdom, wrote in a commentary accompanying the study.

More information

The American Heart Association has more about statins.



-- Robert Preidt



SOURCE: The Lancet, news release, Jan. 11, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. FDA Advisers Reject Over-the-Counter Statin
2. FDA Panel Considering Over-the-Counter Statin
3. FDA Panel to Consider Over-the-Counter Statin
4. Scientists identify gene responsible for statin-induced muscle pain
5. GlaxoSmithKline Obtains Exclusive U.S. OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck & Co., Inc.
6. Burn injuries take devastating toll on nations children
7. Statins After Bypass Lower Stroke Risk
8. Congress called on to replace devastating cuts in Medicare reimbursements by ACP
9. Abbotts Investigational SIMCOR(R) Offers Comparable LDL Lowering to Simvastatin and Significantly Raises HDL and Lowers Triglycerides in Phase III Study
10. Better Prostate Cancer Survival for Men Taking Statins
11. Statins reduce loss of function, keeping old lungs young - even in smokers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/25/2016)... ... 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the ... to iHire in recognition of their exemplary accomplishments in worksite health promotion. , The ... Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... A ... procedures that most people are unfamiliar with. The article goes on to state that ... but also many of these less common operations such as calf and cheek reduction. ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World ... with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... and Scientific Sessions in Dallas that it will receive two significant new grants ... grants came as PHA marked its 25th anniversary by recognizing patients, medical professionals ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 Research and ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" report ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, ... Structural electronics involves electronic and/or electrical components ... replacing dumb structures such as vehicle bodies or ...
(Date:6/24/2016)... 2016 According to a new ... Pen Needles, Safety Pen Needles), Needle Length (4mm, 5mm, ... Mode of Purchase (Retail, Non-Retail) - Trends & Global ... the market for the forecast period of 2016 to ... Billion by 2021 from USD 1.65 Billion in 2016, ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Dialysis Devices Global Market - Forecast to 2022" report ... is the treatment method for the patients with kidney failure, ... and excess fluid from the patient,s blood and thus the ... sodium, potassium and chloride in balance. Increasing ...
Breaking Medicine Technology: