Navigation Links
Statin Therapy Helps Diabetic Patients
Date:1/11/2008

British study finds cholesterol-lowering drugs reduce risk of major vascular events

FRIDAY, Jan. 11 (HealthDay News) -- Most people with diabetes should be considered for treatment with cholesterol-lowering statins.

That's the advice of the authors of a study in the Jan. 12 issue of The Lancet.

The British and Australian researchers found that statins reduced the risk of major vascular events in a wide range of people with diabetes, regardless of age, sex and other clinical characteristics, and irrespective of whether they already had cardiovascular disease.

Diabetes is associated with an increased risk of cardiovascular disease.

For the study, the researchers conducted a meta-analysis of 18,686 people with diabetes and 71,370 without diabetes who took part in 14 randomized trials that examined the use of statins to reduce levels of low-density lipoprotein (LDL), or "bad" cholesterol.

During a mean follow-up of 4.3 years, 3,247 of the people with diabetes experienced vascular events. Among people with diabetes, there was a 9 percent proportional reduction in all-cause death per mmol/L reduction in LDL cholesterol, which was similar to the 13 percent reduction noted in people without diabetes.

The study authors said they found a significant 20 percent proportional reduction in major vascular events per mmol/L reduction in LDL cholesterol in people with diabetes, a decline similar to that seen in people without diabetes.

"This meta-analysis shows convincingly that the proportional benefits of statin therapy on major vascular events were similar in a wide range of individuals with diabetes, including those with no previous history of vascular disease, and benefits were similar to those observed in people without diabetes," the researchers wrote.

"Most people with diabetes should now be considered for statin therapy, unless their risk is low (e.g., as in children) or statin therapy has been shown to be unsuitable for them (e.g., as in pregnancy)," they concluded.

Statins are among the most notable achievements of modern medicine, but "one must not forget the importance of lifestyle changes, such as cessation of smoking, healthy diet, and regular exercise," Bernard Cheung, a professor of clinical pharmacology at the University of Birmingham in the United Kingdom, wrote in a commentary accompanying the study.

More information

The American Heart Association has more about statins.



-- Robert Preidt



SOURCE: The Lancet, news release, Jan. 11, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. FDA Advisers Reject Over-the-Counter Statin
2. FDA Panel Considering Over-the-Counter Statin
3. FDA Panel to Consider Over-the-Counter Statin
4. Scientists identify gene responsible for statin-induced muscle pain
5. GlaxoSmithKline Obtains Exclusive U.S. OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck & Co., Inc.
6. Burn injuries take devastating toll on nations children
7. Statins After Bypass Lower Stroke Risk
8. Congress called on to replace devastating cuts in Medicare reimbursements by ACP
9. Abbotts Investigational SIMCOR(R) Offers Comparable LDL Lowering to Simvastatin and Significantly Raises HDL and Lowers Triglycerides in Phase III Study
10. Better Prostate Cancer Survival for Men Taking Statins
11. Statins reduce loss of function, keeping old lungs young - even in smokers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)... CA (PRWEB) , ... March 22, 2017 , ... ... the California Bay Area providing insurance assistance, financial planning, and related services to ... Endangered Species International to promote awareness of threatened species and wild lands. , ...
(Date:3/22/2017)... ... March 22, 2017 , ... ... Milpitas with a robust, ongoing community enrichment program, has announced their latest charity ... which has provided for the critical needs of homeless families with children for ...
(Date:3/22/2017)... ... March 22, 2017 , ... The American ... prior authorization (PA) form for prescribers to improve patients’ access to the revolutionary ... tools published as part of the article entitled “PCSK9 Inhibitor Access Barriers: ...
(Date:3/22/2017)... (PRWEB) , ... March 22, 2017 , ... Old School ... boxing champ Ashley Theophane as a new Brand Ambassador. Theophane, who trained with Floyd ... welterweight title in 2011. He has racked up an impressive number of wins in ...
(Date:3/22/2017)... ... 2017 , ... Soriant recognizes that identifying savings opportunities can ... facilities across the country are always forced to focus on costs and budgets. ... country, an efficient and quick way to estimate savings potential within specific support ...
Breaking Medicine News(10 mins):
(Date:3/22/2017)... , 22 de marzo de 2017 /PRNewswire/ ... global líder de soluciones de productos y servicios ... hoy que ha adquirido EPL Archives, Inc., una ... los clientes en todo el ciclo de vida ... ofreciendo una muestra de archivo, almacenamiento de documentos ...
(Date:3/22/2017)... DUBLIN , Mar. 22, 2017 Research ... Care Devices Market Analysis & Trends - Industry Forecast to 2025" ... ... to grow at a CAGR of around 10.9% over the next ... This industry report analyzes the market estimates and forecasts for all ...
(Date:3/22/2017)... March 22, 2017  DarioHealth Corp. (NASDAQ: DRIO), ... health and big data solutions, today reported financial ... month period ended December 31, 2016. ... $2.8 million, increased 241% compared to the full ... growth throughout the entire year  ...
Breaking Medicine Technology: