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Statin Side Effects Often Manageable: Study
Date:4/1/2013

etes -- doctors typically prescribe a statin right away.

It's estimated that about 5 percent to 10 percent of patients are truly "statin intolerant," said Dr. Scott Grundy, who wrote an editorial published with the study. If those patients are able to go back on a statin, it's often at a dose that doesn't cut LDL by much, said Grundy, of the University of Texas Southwestern Medical Center in Dallas.

But other types of cholesterol drugs might help, he added.

Drugs known as bile acid sequestrants and cholesterol absorption inhibitors can be used along with statins, according to the U.S National Heart, Lung, and Blood Institute.

For her part, Narula said, "Cardiovascular disease is the No. 1 killer in this country. Our ability to treat high cholesterol is one of the great tools we have against it."

The study was funded by government and private grants. Turchin has received research funds from Merck, which makes Zocor and Mevacor.

More information

Learn more about high cholesterol from the U.S. National Heart, Lung, and Blood Institute.

SOURCES: Alexander Turchin, M.D., researcher, endocrinology, Brigham and Women's Hospital, Boston; Tara Narula, M.D., associate director, cardiac care unit, Lenox Hill Hospital, New York City; April 2, 2013, Annals of Internal Medicine


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