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Starting on 3 drugs at time of diagnosis benefits Type 2 diabetics
Date:6/24/2013

en the response stops, add a class of medication called a sulfonylurea. When those no longer work, the patient is placed on insulin.

Factors for patients, doctors to weigh

Problems with the conventional approach include weight gain, episodes of hypoglycemia and failure to prevent beta cell failure. The conventional approach is less expensive, however.

"We should tell people which drugs work better," Dr. DeFronzo said. "The individuals and doctors need to decide whether they can afford the treatment."

Failure at 10 years out

According to the United Kingdom Prospective Diabetes Study, patients on conventional therapy had an average hemoglobin A1c level of 8.6 percent after a mean of 10 years of follow-up, and nearly two-thirds (65 percent) were on insulin for glucose control.

The Texas Diabetes Institute, a program of University Health System, is the nation's largest and most comprehensive center, entirely devoted to diabetes prevention, treatment, education, professional training and the relentless search for a cure. Texas Diabetes Institute is located where it is most needed, on San Antonio's West Side, where the incidence of diabetes is the highest in the nation.


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Contact: Will Sansom
Sansom@uthscsa.edu
210-567-2579
University of Texas Health Science Center at San Antonio
Source:Eurekalert

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