Working the crimson catwalk were actresses Allison Janney (best known from NBC's The West Wing) and Cheryl Hines (of HBO's Curb Your Enthusiasm), as well as British soul singer Joss Stone and American R&B singer Ashanti -- all wearing red.
The Emmy, Grammy, Tony and Oscar-winning actress Rita Moreno donned a cherry red tulle hat and matching corsage, dancing down the runway. She was followed soon after by Klum, host of Bravo's Project Runway.
The grand finale: screen legend Liza Minelli, who after her own turn on the runway brought the house down with a rousing rendition of "New York, New York."
The stars and their fashions -- from designers Badgley Mischka, Oscar de la Renta, Marc Jacobs, and Calvin Klein, among others -- held the spotlight, but everyone agreed that something much more serious was at stake.
"It's a great cause," Klum said after the show, which was sponsored by Diet Coke. "And it's a great awareness factor. And all these different celebrities are here doing it because it's the number one killer in America, for women. More than all the cancers together. And that's a crazy number."
One in four American women will die from heart disease, Nabel noted, but the campaign's aim is to encourage women to prevent the onset of cardiac illness by leading a healthy lifestyle. That includes eating well, exercising regularly, maintaining an optimal weight, going for routine blood pressure and cholesterol screenings, and avoiding smoking.
Those efforts may be paying off -- on Friday, the NHLBI announced that heart disease deaths for American women declined again in 2005, the last year for which statistics are available. And for the first time ever, that decline has continued for a straight six years, the institute said.
"We're making progress," Nabel said. "Only a third of women in the year 2000 recognized that heart disease is the number one killer. But now, in 20
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