Navigation Links
Stanford researchers sniff out gene that gives dogs black fur
Date:10/30/2007

STANFORD, Calif. - A discovery about the genetics of coat color in dogs could help explain why humans come in different weights and vary in our abilities to cope with stress, a team led by researchers from the Stanford University School of Medicine reports.

The study, published in the Nov. 2 issue of Science, answers a longtime mystery: What determines coat color in dogs" While researchers have known since the 1900s that most mammals share the same genetic mechanism to determine coat color, by the 1950s they began to suspect that dogs were different.

Now after swabbing the inner cheeks of hundreds of dogs and analyzing the DNA in the resulting samples, a team led by genetics professor Greg Barsh, MD, PhD, has nailed the gene. To the researchers' surprise, the gene makes a protein that's part of a large and variable family called defensins, thought to fight infections.

What is clear now is that this protein engages the melanocortin pathway, a circuit of molecular interactions that controls the type of melanin and amount of cortisol produced by the body. Barsh's lab has studied this pathway, which determines skin and hair color as well as stress adaptation and weight regulation, for 15 years.

The discovery of a new participant in this pathway opens up new vistas for drug research, said the article's co-first author, Sophie Candille, PhD, a former graduate student in Barsh's lab. Candille visited five Bay Area dog shows over six months to gather hundreds of samples by gently swabbing the inside of the dogs' cheeks with a brush.

"It's painless for the dogs, so they didn't mind," she said. "The dogs we met at dog shows were very well-behaved and happy to cooperate." Candille also gathered samples from one of Barsh's dogs as well as dogs of her friends and neighbors. And she recruited dog breeders to gather samples and mail them in.

The project began a few years ago with boxers and Large Munsterlanders of differen
'/>"/>

Contact: Rosanne Spector
manishma@stanford.edu
650-725-5374
Stanford University Medical Center
Source:Eurekalert

1

GOOD

Page: 1 2 3

Related medicine news :

1. Stanford Medical Center Implements The First Virtual Cardiac Ultrasound
2. Apollo And Stanford Team To Train Emergency Medical Technicians
3. Stanford Researchers Identify A Gene Causing Downs Syndrome
4. Transgender Experience - A Tool to Analyze Gender Difference By Stanford Scientist
5. Pharmaceutical Companies Banned from Giving Gifts at Stanford
6. Reddy Asks Stanford University to Open Hyderabad Campus
7. Researchers urge caution in using ear tube surgery
8. Researchers Scale to assess the Severity of Epilepsy in Kids
9. Researchers identify the early makers of Neonatal Sepsis
10. OHSU Researchers Announce New Discovery
11. Researchers Identify Gene Connected To Bipolar Disorder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... York, NY (PRWEB) May 20, 2013 ... York City, today announced the introduction of its new ... powder that provides high density nutrition with plant extracts ... vegetables, herbs, spices, royal jelly, apple pectin, plant enzymes ... Hx™ offers the micronutrients and antioxidant levels of several ...
(Date:5/20/2013)... Hills, Utah (PRWEB) May 20, 2013 As a ... can be to effectively balance family, work, and a fit, healthy ... weight gain. , “It hit me like a ton of bricks ... Arnold. “I woke up one morning and realized I had lost ... time. I felt awful, I had little to no energy to ...
(Date:5/19/2013)... New York, NY (PRWEB) May 20, 2013 ... announce that they are representing a New York woman in ... running back with the National Football League (NFL). According ... Court, the Petitioner is seeking a declaration of paternity, order ... on behalf of her son with Mr. Walker. (Docket ...
(Date:5/19/2013)... Calif., May 20, 2013 Whole-cell pertussis vaccines ... acellular pertussis vaccines during a large recent outbreak, ... in Pediatrics . , Whole-cell pertussis vaccines, ... to 1990s, but were associated with safety concerns ... pertussis vaccines, which are also called DTaP. By ...
(Date:5/19/2013)... Alonso Krangle LLP a dedicated law ... lawsuit on behalf of a-24-year-old financial analyst rendered quadriplegic ... The diving accident lawsuit, which was filed in the Supreme ... Defendant held the property out as a bathing beach, but ... area. (Case No. 34556/12) , According to the diving accident ...
Breaking Medicine News(10 mins):Health News:InVite® Health Introduces New Food-Based Dietary Supplement – Greens Hx™ 2Health News:InVite® Health Introduces New Food-Based Dietary Supplement – Greens Hx™ 3Health News:New Program Helps Busy Moms Become Healthier, Lose Weight, and Feel Great 2Health News:New York Woman in Paternity Petition Against Former NFL Running Back, Herschel Walker, Alonso Krangle LLP Representing Petitioner 2Health News:New York Woman in Paternity Petition Against Former NFL Running Back, Herschel Walker, Alonso Krangle LLP Representing Petitioner 3Health News:Whole-cell vaccine was more effective than acellular vaccine during CA pertussis outbreak 2Health News:Whole-cell vaccine was more effective than acellular vaccine during CA pertussis outbreak 3Health News:Alonso Krangle Files Diving Accident Lawsuit on Behalf of Suffolk County Man Rendered Quadraplegic in Tragic Diving Accident at Long Island Beach 2Health News:Alonso Krangle Files Diving Accident Lawsuit on Behalf of Suffolk County Man Rendered Quadraplegic in Tragic Diving Accident at Long Island Beach 3
... Ulagu”,Wondering what the above verses from Thirukurral written by ... special report about nanotechnology? // , ,“ Annuvai ... the ingenuity of its author, that he has compressed ... as if he had hollowed an atom, and enclosed ...
... proposes to change the curriculum for medicine by integrating ... within two years., ,"Today's medical curriculum is ... the modern and traditional practices in the new curriculum. ... time," said health minister, Ramadoss during National Seminar on ...
... men and occurs in men 65 years or older. It ... should undergo the routine examination of prostate and also test ... levels of PSA in blood. African-American men or men with ... screening exams at an earlier age. Signs and symptoms of ...
... that more and more women are now opting for ... new study in the September issue of the journal ... delivery become more varied and sophisticated, growing numbers of ... childbirth., ,Researchers from the University of Colorado had ...
... acne for more than six weeks were more than ... infection within one year as individuals with acne who ... study reports., ,Overuse of antibiotics has been held ... increase in increase in infectious illness. The present study ...
... is a genetic disorder characterized by distorted, sickle shaped red ... and organ damage to the kidneys, spleen, and liver. The ... the incidence is about 1 in 500., ,Despite much ... disease. Pain can be relieved, and the frequency and duration ...
Cached Medicine News:Health News:Scientists Consider About New Technology Called Nanotechnology 2Health News:Hydroxyurea Treatment For Children With Sickle Cell Disease 2
(Date:5/17/2013)... SAN DIEGO , May 17, 2013 /PRNewswire/ ... today that its Fast-Track Advanced Technology Small Business ... National Institute of Allergy and Infectious Diseases (NIAID), ... (NIH), supporting the development of novel human antibody ... S. aureus or Staph) infections, including methicillin-resistant ...
(Date:5/17/2013)... CHAMPAIGN, Ill. , May 17, 2013  Sony ... new Sony SP6800 Spectral Analyzer (SP6800).  Sony will be ... 2013, which will be held at the ... San Diego, California , from May 20 - ... Sony,s second analytical system, incorporating commercial audio-visual technologies into ...
(Date:5/17/2013)... , May 17, 2013 /PRNewswire-iReach/ -- The ... recombinant proteins, is placing renewed emphasis on alternate ... rise as a number of factors are converging ... pharmaceutical makers and their delivery device partners . ... refractory conditions, the growing trend toward self-administration for ...
Breaking Medicine Technology:Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 2Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 3Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 4Sony Biotechnology Inc.'s New Technology for Science Provides Researchers Results in Color 2Pharmaceutical Makers and Delivery Device Partners Rethink Delivery Technologies - New Report Examines this Evolving Segment 2Pharmaceutical Makers and Delivery Device Partners Rethink Delivery Technologies - New Report Examines this Evolving Segment 3
... Fla., Oct. 20, 2011 China Nuvo Solar Energy, ... Nevada has approved the Company,s requested corporate name change to ... and authorized the Board of Directors to change the Company,s ... of the Parent. As a result of the Nevada approval, ...
... FREMONT, Calif., Oct. 20, 2011 WaferGen Biosystems, ... announced organizational changes to strengthen domain leadership and ... of its SmartChip System.   As ... Lombardi, formerly President and a director of Helicos ...
Cached Medicine Technology:China Nuvo Solar, Inc. Announces Corporate Name Change to SurgLine International, Inc. 2WaferGen Announces Organizational Changes to Enhance Commercialization of SmartChip System 2WaferGen Announces Organizational Changes to Enhance Commercialization of SmartChip System 3
... table that performs as well as your ... use in major surgical suites where control ... B 810 brings better patient outcomes within ... articulation for maximum patient positioning and allows ...
Clearview Chlamydia is a rapid, easy-to-use test for the detection of Chlamydia trachomatis from female endocervical swab specimens....
10-mm (0.4-in) diameter cups have multi-color lead wires and 2-mm (0.08-in) holes for easy paste/collodion application. Available in a variety of lengths to suit many different needs....
... these head cap systems are packaged to ... Each Electro-Cap System features pure tin electrodes ... When you place your order, please specify ... head cap system and whether you want ...
Medicine Products: