Navigation Links
Stanford researchers find molecule that kills kidney cancer cells
Date:7/7/2008

STANFORD, Calif. - Kidney cancer patients generally have one option for beating their disease: surgery to remove the organ.

But that could change, thanks to a new molecule found by Stanford University School of Medicine researchers that kills kidney cancer cells. Ideally, the researchers said, a drug created from this molecule would help fight the life-threatening disease while leaving patients' kidneys intact.

"You now have a potential means of going after a disease that's been difficult to treat," said Amato Giaccia, PhD, professor and director of radiation oncology and radiation biology at the medical school. His findings will be published in the journal Cancer Cell on July 8.

Giaccia said his lab focused on renal cell carcinoma, or kidney cancer, because there is no known cure for it short of removing a damaged kidney from a patient's body. "There is no effective chemotherapy to treat renal cell carcinoma," said Giaccia, also a researcher at the Stanford Cancer Center. "Patients still succumb."

Almost 54,400 people in the United States will be diagnosed with kidney cancer this year, and about 13,000 will die from the disease, according to the American Cancer Society. Radiotherapy, a powerful weapon used to fight cancer, has also proven to be ineffective in killing kidney cancer, in contrast to other types of cancer, Giaccia said.

This new research could lead to a treatment to save patients from losing one of their two kidneys. The organs are responsible for filtering blood, controlling blood pressure and preventing anemia, among other tasks.

Giaccia's work focuses on the von Hippel-Lindau tumor suppressor gene, or VHL gene, which normally slows tumor growth in humans but does not work in 75 percent of kidney tumor cells. Giaccia's team searched for a small molecule that would kill cancer cells when this VHL gene is broken. They found their weapon in a molecule called STF-62247.

While S
'/>"/>

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Cancer cells revert to normal at specific signal threshold, Stanford researchers find
2. The Sir Allen Stanford Pediatric Fellowship Program Provides Close To CHF 1 Million to Support Kinderspital Zurich
3. Antibiotics can prevent wound complications of childbirth, Stanford/Packard study finds
4. GlaxoSmithKline Announces $500,000 in Fellowships at Stanford Graduate School of Business
5. Stanford Professor Barry M. Trost Visits WuXi PharmaTech and Gives Two Seminars
6. Vital Images Showcases the ViTAL Enterprise Solution at Stanford Universitys 6th Annual Face-Off
7. Brooks Brothers CEO at St. Jude Childrens Research Hospital(R) To Announce Partnership With Stanford St. Jude Championship
8. Stanford researchers synthesize compound to flush HIV out of hiding
9. High blood pressure still sneaking past doctors, Stanford study shows
10. Inaugural Stanford International Pro-Am Winner A Remarkable Story in Determination And the Powerful Impact of St. Jude Childrens Research Hospital
11. Defending Champion Woody Austin Helps Memphis Kick-off Countdown to 2008 Stanford St. Jude Championship
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... The British Menopause Society and Women,s Health Concern have ... to provide clarity around the role of HRT, the ... the society,s flagship title, Menopause International , published ... HRT has changed from being branded the "elixir of ... be used in certain circumstances. Since the publication of ...
(Date:5/24/2013)... Today marks the launch of Destination ... , The redesigned and enhanced Itinerary Builder will ... on their computer or mobile device that they can ... allows users to fill in their date of arrival ... their choice of vacation packages, accommodations, restaurants, and things ...
(Date:5/24/2013)... Wixom, MI (PRWEB) May 24, 2013 ... recent Cute Baby Photo Contest. Lindsey Willis of Olathe, ... Cuties-brand diapers from DiaperBuys. Second prize was a ... Heather Tacher, North Las Vegas, Nev.; and third prize, ... Texas. , The contest was run through the company’s ...
(Date:5/24/2013)... 2013 Wednesday, 15th May 2013 | 10am ... to access webinar playback: http://bit.ly/10Rt0ZH , Ongoing regulatory ... markets. Across the globe and particularly in Europe, a number ... M&A activity . For dealmakers, understanding how the likes of ... Tax’ affects your corner of the market will give you ...
(Date:5/24/2013)... San Diego, CA (PRWEB) May 24, 2013 ... informing consumers today of the latest update involving ... Zithromax and Zmax SR (azithromycin) can allegedly ... Canadian Broadcasting Company reported on May 17, 2013* ... and Drug Administration in warning that Zithromax can ...
Breaking Medicine News(10 mins):Health News:Create and Win the Perfect Halifax Getaway with the All-New Itinerary Builder 2Health News:DiaperBuys.com Announces Photo Contest Winners 2Health News:Register to Access Webinar Playback - The Impact of Financial Regulation on M&A in 2013 2Health News:Register to Access Webinar Playback - The Impact of Financial Regulation on M&A in 2013 3Health News:2013 Alleged Zithromax Arrhythmia and Sudden Death Cases Update: Canadian Health Officials Issue Warning 2Health News:2013 Alleged Zithromax Arrhythmia and Sudden Death Cases Update: Canadian Health Officials Issue Warning 3Health News:2013 Alleged Zithromax Arrhythmia and Sudden Death Cases Update: Canadian Health Officials Issue Warning 4
... implants created using stem cells can only be constructed ... before the almost inevitable need for total joint replacement. ... investigating the possibilities of a biologically-engineered synthetic liquid polymer ... offering a one stop, permanent solution. ...
... caregivers to hospital patients, coordinating and providing direct care and delivering ... ensure that each of its patient-care units has an adequate number ... number of hours nurses work known as the "target level" ... flow of patients and their need for care. Too many nurses ...
... By Amanda Gardner HealthDay Reporter , WEDNESDAY, March ... target levels in a large hospital, more patients died, a ... an era of nursing shortages and cost-cutting, in that the ... authors of the research, appearing in the March 17 issue ...
... By Amanda Gardner HealthDay Reporter , ... the tsunami that devastated the nuclear complex in Japan ... that any radiation from the unfolding disaster across the ... say. The chances of any radioactive plume reaching ...
... Gardner HealthDay Reporter , WEDNESDAY, March 16 (HealthDay ... treatment to show a benefit for women with a rare ... even a treatment. The drug, sirolimus (Rapamycin), improved both ... lymphangioleiomyomatosis, or LAM, according to a study published online March ...
... recent study from North Carolina State University shows that while ... has grown, fund support for park operations has been significantly ... growth endangers the more than $20 billion in economic impact ... the reduction in general-fund support for operations puts stress on ...
Cached Medicine News:Health News:Liquid biomaterials take stem cell therapy to new level 2Health News:Risk of hospital patient mortality increases with nurse staffing shortfalls, study finds 2Health News:Risk of hospital patient mortality increases with nurse staffing shortfalls, study finds 3Health News:When Nurse Staffing Drops, Mortality Rates Rise: Study 2Health News:Radiation From Japan's Nuke Disaster Unlikely to Threaten U.S., Experts Say 2Health News:Radiation From Japan's Nuke Disaster Unlikely to Threaten U.S., Experts Say 3Health News:Radiation From Japan's Nuke Disaster Unlikely to Threaten U.S., Experts Say 4Health News:Transplant Drug May Fight Rare Lung Disorder 2Health News:Transplant Drug May Fight Rare Lung Disorder 3Health News:Study shows attendance at state parks grows, even as funding decreases 2
(Date:5/24/2013)... 24, 2013 China Biologic Products, Inc. (Nasdaq: ... integrated plasma-based biopharmaceutical company in China ... from a public announcement issued by Shanghai RAAS Blood ... on Shenzhen Stock Exchange, that on May 21, 2013, ... Chan"), one of the shareholders of the Company, and ...
(Date:5/24/2013)... CHESTERBROOK, Pa. , May 24, 2013  Auxilium ... that executive management will participate in the Deutsche Bank ... the Westin Boston Waterfront Hotel.  Mr. Adrian ... scheduled to present an overview of the Company and ... May 29, 2013.   (Logo: http://photos.prnewswire.com/prnh/20101202/MM10881LOGO ...
(Date:5/24/2013)... , May 24, 2013 In accordance with Rule ... Rule 14e-1 of the United States Exchange Act, Echo Pharma ... offer for Elan Corporation (NYSE: ELN). Background ... Pharma") made an offer for the entire of the issued ... ("Elan") (the "Original Offer").  On 20 May ...
Breaking Medicine Technology:China Biologic Comments on the Proposed Shanghai RAAS Transaction 2China Biologic Comments on the Proposed Shanghai RAAS Transaction 3China Biologic Comments on the Proposed Shanghai RAAS Transaction 4Auxilium Pharmaceuticals, Inc. To Present At The Deutsche Bank Health Care Conference 2Auxilium Pharmaceuticals, Inc. To Present At The Deutsche Bank Health Care Conference 3Auxilium Pharmaceuticals, Inc. To Present At The Deutsche Bank Health Care Conference 4Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 2Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 3Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 4Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 5Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 6Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 7Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 8Royalty Pharma Discloses Acceptance Levels of Original Offer for Elan Pursuant to Irish and United States Regulatory Requirements 9
... 2012 Futuremed Healthcare Products Corporation ("Futuremed") (TSX: FMD) ... wholly-owned subsidiary of Cardinal Health, Inc. (NYSE: ... a ,no action letter, this morning regarding Cardinal Health ... shares ("Common Shares") of Futuremed for CAD $8.15 per ...
... Mich., Feb. 16, 2012  Ministry Health Care, a ... Minnesota, has become one of only 17 hospital ... electronic medical record systems.  This milestone was accomplished ... a new Meaningful Use Quality Manager product to ...
Cached Medicine Technology:Cardinal Health Canada Inc. Receives Competition Bureau Clearance for Acquisition of Futuremed 2Cardinal Health Canada Inc. Receives Competition Bureau Clearance for Acquisition of Futuremed 3Cardinal Health Canada Inc. Receives Competition Bureau Clearance for Acquisition of Futuremed 4Thomson Reuters Teams With Ministry Health Care to Develop Meaningful Use Quality Manager 2Thomson Reuters Teams With Ministry Health Care to Develop Meaningful Use Quality Manager 3
... TME 227 T is a ... temporary cardiac pacing and monitoring ... The TME 227 T features ... myocardium, which allows safe and ...
For temporary cardiac pacing after open heart surgery. The zig-zag portion of the heartwire is embedded into the desired area of the myocardium (epicardially)....
For temporary cardiac pacing after open heart surgery. The zig-zag portion of the heartwire is embedded into the desired area of the myocardium (epicardially)....
For temporary cardiac pacing after open heart surgery. The zig-zag portion of the heartwire is embedded into the desired area of the myocardium (epicardially)....
Medicine Products: