Navigation Links
Stanford-led study disproves link between genetic variant, risk of coronary artery disease
Date:10/7/2010

erstandably great desire to use the information about human genetics that's been amassing since the sequencing of the human genome 10 years ago, said Quertermous, who has worked in the field for more than 20 years. "It's something I've been waiting for, for a long time."

That's because the well-known risk factors for atherosclerosis, such as high cholesterol, smoking, diabetes and high blood pressure, appear to account for only about half the variation of rates of coronary disease observed in human populations. The balance of variation is likely explained by a combination of inherited variants in or near genes that are important in the pathogenesis of disease in addition to other unrecognized, adverse environmental exposures.

"Using genetics to help improve our ability to predict coronary disease is particularly important because we have several different classes of drugs at our disposal that can substantially reduce the risk of heart attacks" said Assimes. "But we still need to be careful about what we put into practice and not get carried away too quickly. We know from previous experience that a positive association between a genetic variant and a common disease, such as coronary disease, needs to be consistently observed in many human population studies before it can be believed."

In fact, Quertermous points out that even for the roughly one dozen genetic markers that have been successfully validated to date, evidence to support their use in clinical practice is lacking. However, this situation will likely change in the near future as researchers reliably identify more genetic markers.

The data collections used in this study were supported by more than 30 institutions including government and nonprofit agencies and the following companies: Astra Zeneca, Berlin Chemie, Boots Healthcare, deCODE genetics, Glaxo-Smith-Kline, McNeil Pharma (former Woelm Pharma), MSD Sharp & Dohme and Pfizer.


'/>"/>

Contact: Susan Ipaktchian
susani@stanford.edu
650-725-5375
Stanford University Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford-led team validates, extends fMRI research on brain activity
2. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
3. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
4. TV drama can be more persuasive than news program, study finds
5. Study carried out into biological risks of eating reptiles
6. Neuroimaging study may pave way for effective Alzheimers treatments
7. Study finds racial gaps continue in heart disease awareness
8. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
9. First blinded study of venous insufficiency prevalence in MS shows promising results
10. Soothing infants with food focus of childhood obesity study
11. People with anxiety disorder less able to regulate response to negative emotions, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... Kenosha, WIsconsin (PRWEB) , ... July 02, 2015 ... ... Luminaires for the parking structure retrofit project at the University of Minnesota, they ... know is that it would also be an award-winning choice: the total energy ...
(Date:7/2/2015)... , ... July 02, 2015 , ... In 2012, Patrick Achebe realized that the gift ... alone. He sat down to write his first poem, and three years later he was ... was special and worth sharing with the world. "I have always believed that the best ...
(Date:7/2/2015)... GA (PRWEB) , ... July 02, 2015 , ... ... sporting the newest shades of the SIGVARIS PERFORMANCE SOCKS. Since the socks were ... experts and athletic trainers. Their significant popularity has inspired four new, fun shades ...
(Date:7/2/2015)... ... July 02, 2015 , ... The ZAC Foundation, a national ... season with important lessons on how to stay water safe with the help of ... Swim, authored by The ZAC Foundation co-founders, follows Zeke’s water safety journey. Zeke, ...
(Date:7/2/2015)... ... July 02, 2015 , ... ... 2015” provides comprehensive information on the pipeline products with comparative analysis of ... wound therapy (NPWT) with 22 market data tables and 4 figures, spread ...
Breaking Medicine News(10 mins):Health News:Kenall’s TekDek™ Helps University Achieve Award-Winning Energy Savings in Parking Structure Lighting Retrofit 2Health News:Patrick Achebe Releases Debut Book, Whispering Waves: Poems for Everyday Grace 2Health News:SIGVARIS is Sporting Four Brand New Colors in the Popular PERFORMANCE SOCK Product Line 2Health News:The ZAC Foundation Kicks Off Summer and July 4th Weekend with Complimentary Children’s E-Book on Water Safety 2Health News:The ZAC Foundation Kicks Off Summer and July 4th Weekend with Complimentary Children’s E-Book on Water Safety 3Health News:Negative Pressure Wound Therapy (System, Wound Care, Tissue Cooling NPWT) Pipeline Review 2015 Market Research Report Available at RnRMarketResearch.com 2Health News:Negative Pressure Wound Therapy (System, Wound Care, Tissue Cooling NPWT) Pipeline Review 2015 Market Research Report Available at RnRMarketResearch.com 3Health News:Negative Pressure Wound Therapy (System, Wound Care, Tissue Cooling NPWT) Pipeline Review 2015 Market Research Report Available at RnRMarketResearch.com 4
... ... Habits for Kids , ... Los Angeles, Calif. (PRWEB) March 23, 2010 -- Healthy lifestyles and kids’ nutrition ... by First Lady Michele Obama and schools to Jamie Oliver’s Food Revolution television show ...
... ... offered at three different locations in central Illinois in mid-April. The conference will ... health record systems in their medical practice. The summit is jointly sponsored ... of Medicine at Peoria and is free to attendees. , ...
... height in postmenopausal women may indicate a vertebral fracture, ... Medical Association Journal ) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj090710.pdf ... and is associated with back pain. Causes include changes ... discs and vertebral fractures. Two-thirds of adults have back ...
... , ... United States applauds the House of Representative’s passage of the historic health care reform legislation ... , ... Arc of the United States applauds the House of Representative’s passage of the historic ...
... organization in France , announced today that it has started a new collaboration with award-winning ad agency Goodby, Silverstein & Partners. , ... , , ... ... ...
... a rate of cognitive decline four times greater than those ... researchers at Rush University Medical Center in Chicago. The results ... to quantify the rate of cognitive decline in Alzheimer,s disease, ... journal Neurology, the medical journal of the American ...
Cached Medicine News:Health News:Create Healthy Easter Baskets – Join the Food Revolution 2Health News:Create Healthy Easter Baskets – Join the Food Revolution 3Health News:Create Healthy Easter Baskets – Join the Food Revolution 4Health News:Central Illinois Electronic Health Records Summit Coming in April;,Medical Conference Offered In Three Central Illinois Locations 2Health News:Central Illinois Electronic Health Records Summit Coming in April;,Medical Conference Offered In Three Central Illinois Locations 3Health News:Central Illinois Electronic Health Records Summit Coming in April;,Medical Conference Offered In Three Central Illinois Locations 4Health News:The Arc Applauds House Passage of Health Care Reform Legislation 2Health News:The Arc Applauds House Passage of Health Care Reform Legislation 3Health News:French-Based Non-Profit 'AIDES' is Starting a New Collaboration With Goodby, Silverstein & Partners 2Health News:French-Based Non-Profit 'AIDES' is Starting a New Collaboration With Goodby, Silverstein & Partners 3Health News:Cognition declines 4 times faster in people with Alzheimer's disease than those with no dementia 2
(Date:7/2/2015)... DUBLIN , June 25, 2015 ... the addition of the "Veterinary / Animal Vaccines ... to 2020" report to their offering. ... $7,197.9 Million by 2020 from $5,507.3 Million in 2015, ... Major factors fueling market growth are growing ...
(Date:7/2/2015)... Legal-Bay LLC, The Lawsuit Settlement Funding Company, ... in the Southern District of West ... against Ethicon for a single trial to take place ... 26 women include claims from the women plaintiffs that ... & Johnson,s Ethicon subsidiary. The cases against Ethicon are ...
(Date:7/2/2015)... Agreement reinforces ViiV ...   ViiV Healthcare and Desano Pharmaceuticals (Desano) today ... China of dolutegravir. The agreement will offer ... and will allow ViiV Healthcare to offer a competitive supply ... Tivicay®) for China and a number ...
Breaking Medicine Technology:Veterinary / Animal Vaccines Market 2015 - Global Forecast to 2020 for the $7.19 Billion Industry 2Judge Sets Single Trial for 26 Ethicon Mesh Cases, says Legal-Bay Lawsuit Settlement Funding 2Judge Sets Single Trial for 26 Ethicon Mesh Cases, says Legal-Bay Lawsuit Settlement Funding 3ViiV Healthcare and Desano Pharmaceuticals' Manufacturing Agreement Will Allow Competitive Supply of Dolutegravir in China and Several Developing Countries 2ViiV Healthcare and Desano Pharmaceuticals' Manufacturing Agreement Will Allow Competitive Supply of Dolutegravir in China and Several Developing Countries 3ViiV Healthcare and Desano Pharmaceuticals' Manufacturing Agreement Will Allow Competitive Supply of Dolutegravir in China and Several Developing Countries 4ViiV Healthcare and Desano Pharmaceuticals' Manufacturing Agreement Will Allow Competitive Supply of Dolutegravir in China and Several Developing Countries 5ViiV Healthcare and Desano Pharmaceuticals' Manufacturing Agreement Will Allow Competitive Supply of Dolutegravir in China and Several Developing Countries 6
... BEIJING , July 7 /PRNewswire-Asia-FirstCall/ -- Concord ... CCM ), operator of,the largest network of radiotherapy and ... has filed its annual report for the fiscal year ended, ... Securities and Exchange,Commission on June 30, 2010 . The ...
... HARBIN, China , July 6 /PRNewswire-Asia-FirstCall/ -- ... or the,"Company"), a leading developer, manufacturer and marketer of ... other,health and nutritional products in the People,s Republic ... the Global Hunter 2010 China Conference,on Tuesday, July ...
Cached Medicine Technology:Concord Medical Files 2009 Annual Report on Form 20-F 2Weikang Bio-Technology to Present at Global Hunter 2010 China Conference on July 13, 2010 2Weikang Bio-Technology to Present at Global Hunter 2010 China Conference on July 13, 2010 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: