Navigation Links
Stanford computer algorithm used to identify bladder cancer marker
Date:1/17/2012

ch strategy had been demonstrated in a research paper published in PNAS in 2010 that looked at development of immunological cells in mice (http://med.stanford.edu/ism/2010/march/boolean.html). Using this technique, they found another molecule, keratin-14, that was associated with less-differentiated, more-primitive bladder cells.

With this information in hand, they hypothesized that bladder cancers generally come in three types corresponding to the different forms of keratin, and that the bladder cancer cells making keratin-14 would be the most malignant. The researchers then found cell surface markers unique to each of these types of cells and used antibodies to collect purified cells for further experiment.

The validity of this approach was confirmed when the scientists analyzed pathological samples from former bladder cancer patients and found that the presence of cells creating keratin-14 were indeed associated with worse prognoses. The researchers also used their antibodies to isolate different types of bladder cancer cells and showed that the "primitive" cells associated with keratin-14 could cause the most aggressive cancer when transplanted into mice.

While a bladder cancer test that uses antibody staining will not replace staging and grading by a pathologist, it offers additional information that can lead to more accurate diagnosis. "It also can provide rapid information about the cancer in rural areas or poor countries where a pathologist experienced with bladder cancer may not be immediately available," said Sahoo, the researcher who developed the Boolean search algorithm.


'/>"/>
Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California
2. Interleukin Genetics, Inc. and Stanford University Report Genetic Test Improves Weight Loss Success With Diets
3. Mathematical innovation turns blood draw into information gold mine in Stanford study
4. Nanoscale stealth probe slides into cell walls seamlessly, say Stanford engineers
5. Eating disorder cutoffs miss some of sickest patients, Stanford/Packard study finds
6. Plant pathogen genetically tailors attacks to each part of host, say Stanford researchers
7. Stanford-led team validates, extends fMRI research on brain activity
8. Stanford/Packard study finds surprising disparity in where chronically ill kids hospitalized
9. Orphaned elderly serious casualty of African AIDS epidemic, Stanford study finds
10. Pro Ana Versus Pro Recovery Sites: New Study by Johns Hopkins and Stanford University raises concerns.
11. Melanoma-initiating cell identified by Stanford scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2014)... Benaroya Research Institute at Virginia Mason (BRI) recently received ... in metastatic breast cancer reduces both the growth of ... scientists have found in models of the disease that ... 80 percent and can keep the tumor from metastasizing ... grant comes from the National Cancer Institute of the ...
(Date:4/18/2014)... Northwestern Medicine scientists could lead to potential new treatments ... with scleroderma. , Fibrosis, or scarring, is a ... skin and lungs can lead to serious organ damage ... new therapeutic options centers on findings made by Swati ... the role that a specific protein plays in promoting ...
(Date:4/17/2014)... targets that could be used to provide relief ... London made the discovery when researching how pain ... body. , Dr Marzia Malcangio said: "We have ... and our findings could help chemotherapy patients who ... side effect of some chemotherapy drugs (such as ...
(Date:4/17/2014)... San Diego School of Medicine report that older women, ... major loss are more likely to be compassionate toward ... published in this month,s issue of the International ... are associated with better health and well-being as we ... improve the outcomes of individuals whose deficits in compassion ...
(Date:4/17/2014)... Northwestern University synthetic biology team has created a ... programmable therapeutics that could travel the body and ... , Engineering cell-based, biological devices that monitor and ... clinical synthetic biology. However, no existing technology enabled ... patient,s physiological state and respond in a customized ...
Breaking Medicine News(10 mins):Health News:Benaroya Research Institute evaluates immunology approach to blocking breast cancer 2Health News:New clues on tissue scarring in scleroderma 2Health News:New pain relief targets discovered 2Health News:The ilk of human kindness 2Health News:Building 'smart' cell-based therapies 2
... Glan Clywd Hospital will soon offer local cancer patients ... radiotherapy technology on two new treatment machines from Varian ... the Clinac(R) linear accelerators with RapidArc are installed, the ... to offer this new, faster form of radiotherapy that ...
... (NYSE: DHR ) announced today that ... quarterly dividend of $0.03 per share payable on ... June 26, 2009.Danaher Corporation is a leading manufacturer ... Tools and Components ( www.danaher.com ). ...
... Outpatient, Inpatient SettingsBOSTON, May 7 MedAptus(R), market ... the distinguished Lenox Hill Interventional Cardiac & Vascular ... to implement Professional Intelligent Charge Capture. Nearly ... of the most highly respected cardiovascular care programs ...
... Ohio, May 7 STERIS Corporation (NYSE: STE ... a 38% increase in its quarterly dividend to $0.11 per ... to shareholders of record at the close of business on ... of STERIS Corporation is to provide a healthier today and ...
... EPS Guidance , WARSAW, Ind., May 7 First Quarter 2009 Highlights: ... Revenue of $101.4 million, comparable year-over-year and up 6.8% on a constant currency ... 24.2%, up 70 basis points year-over-year and up 80 basis points over the ... Operating income of $11.2 million, up 17.2% year-over-year and up 18.2% over the ...
... a.m. EDT at www.isispharm.com CARLSBAD, Calif., May 7 ... announced its financial results for the quarter ended March 31, ... gain that Isis recognized from selling its Ibis Biosciences subsidiary ... of 2009 with pro forma net income of $173.0 million. ...
Cached Medicine News:Health News:Cancer Patients in North Wales to Gain Access to Varian's RapidArc Radiotherapy Treatments 2Health News:MedAptus' Charge Capture Technology Deployed at Leading Manhattan Cardiovascular Practice 2Health News:MedAptus' Charge Capture Technology Deployed at Leading Manhattan Cardiovascular Practice 3Health News:STERIS Corporation Announces Quarterly Dividend Increase of 38% 2Health News:STERIS Corporation Announces Quarterly Dividend Increase of 38% 3Health News:Symmetry Medical Reports First Quarter 2009 Financial Results 2Health News:Symmetry Medical Reports First Quarter 2009 Financial Results 3Health News:Symmetry Medical Reports First Quarter 2009 Financial Results 4Health News:Symmetry Medical Reports First Quarter 2009 Financial Results 5Health News:Symmetry Medical Reports First Quarter 2009 Financial Results 6Health News:Symmetry Medical Reports First Quarter 2009 Financial Results 7Health News:Symmetry Medical Reports First Quarter 2009 Financial Results 8Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 2Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 3Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 4Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 5Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 6Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 7Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 8Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 9Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 10Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 11Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 12Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 13Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 14Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 15Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 16Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 17Health News:Isis Reports Strong Financial Results and Highlights for First Quarter of 2009 18
(Date:1/15/2014)... 2014 AARP Foundation today announced it has established a ... the severe cold weather that has gripped much of the ... in need; so to support these emergency relief efforts AARP ... which could mean up to $500,000 in aid. The matching ...
(Date:1/15/2014)... 15, 2014 Massachusetts General Hospital (MGH), the ... ) announced today that they have launched a ... therapeutic targets and develop novel therapies for inflammatory ... millions worldwide. The MGH-Broad-Amgen collaboration brings together scientists ...
(Date:1/15/2014)... NEW YORK , January 15, 2014 ... BreedIT Ltd., the exclusive worldwide distributor of highly sophisticated ... that on January 7, 2014, the Company,s board of ... Ben-Zion Weiner as its new member of the ...
Breaking Medicine Technology:AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3
For use with E0828 A needle tip and E0828 B gouge tip. Round knurled with threaded ended for tips. Most popular size or model....
Handle will hold E0824 A replacement burrs and E0813 Pterigium diamond burrs. Round knurled handle. Most popular size or model....
Set consists of one each:E0824 A replacement burr set. E0824 B handle....
0.5 mm replacement burr for Algerbrush rust ring remover (E0815 A). Burr can also be used with Algerbrush rust ring remover (E0815 B). Dull finish....
Medicine Products: