Navigation Links
Standard Dose of Blood Thinner May Not Be Best for All Patients
Date:11/6/2012

TUESDAY, Nov. 6 (HealthDay News) -- Seventy-five percent of patients taking the widely used blood thinners clopidogrel (Plavix) and prasugrel (Effient) are getting the incorrect dose and could be at risk for serious problems such as uncontrolled bleeding or blood clots, a new study contends.

Millions of Americans with coronary artery disease take the drugs to prevent blood clots that could cause a heart attack or stroke. Guidelines recommend that all patients take the same standardized dose, but that dose is not effective for all patients, according to researchers at the Intermountain Medical Center Heart Institute in Salt Lake City.

The researchers looked at more than 500 patients and found that half of patients taking Plavix were getting too little of the drug to most effectively prevent blood clots, while a quarter were getting too much. Only a quarter were receiving an appropriate dose.

Among patients taking Effient, half were taking too much of the drug, which could lead to dangerous bleeding. A quarter were taking too little of the drug and a quarter were taking the appropriate dose.

The researchers also concluded that indicators like age, gender, cholesterol levels and history of heart problems were not good predictors for how a patient would react to the blood thinners.

"There's a sweet spot, an appropriate range for each patient. But we found that not many people are falling into that range," cardiac researcher Dr. Brent Muhlestein said in an institute news release.

"We showed that by performing a simple blood test to see whether or not the blood is clotting properly, we can determine whether patients are getting an appropriate, individualized dose of the medications," he added. "The test is easy to perform, but not widely used."

The study was presented Tuesday at the American Heart Association annual meeting in Los Angeles. The data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. Agency for Healthcare Research and Quality has more about blood thinners.

-- Robert Preidt

SOURCE: Intermountain Medical Center Heart Institute, news release, Nov. 6, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New research suggests standardized booster seat laws could save lives of children
2. Settings standards for research into Rett syndrome
3. Standard chemotherapy provides higher survival rate than experimental in lung cancer patients
4. First validated method for analyzing flavanols and procyanidins in cocoa products could help scientists and the industry in standardized reporting
5. Gold standards of success defined for AF ablation
6. CRT consensus set to standardize and improve care for patients worldwide
7. New device to remove stroke-causing blood clots proves better than standard tool
8. Alcohol advertising standards violations most common in magazines with youthful audiences
9. Standard radiation therapy dose provides pain relief for painful heel spurs
10. New technology represents next-generation tool for detecting substandard and counterfeit medicines
11. Adding Vitamin B12 to Standard Drugs Might Help Fight Hepatitis C
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Standard Dose of Blood Thinner May Not Be Best for All Patients
(Date:6/27/2016)... California (PRWEB) , ... June 27, 2016 , ... "FCPX ... fully customizable inside of Final Cut Pro X," said Christina Austin - CEO of ... unique style. Final Cut Pro X users can now reveal the media ...
(Date:6/26/2016)... ... 2016 , ... Quality metrics are proliferating in cancer care, and are derived ... eye of the beholder, according to experts who offered insights and commentary in the ... Care. For the full issue, click here . , For the American Society ...
(Date:6/26/2016)... ... June 26, 2016 , ... ... have been diagnosed with endometriosis. These women need a treatment plan to not ... comprehensive approach that can help for preservation of fertility and ultimately achieving a ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency ... named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director ...
(Date:6/24/2016)... Los Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... plastic surgery procedures that most people are unfamiliar with. The article goes on to ... known procedures, but also many of these less common operations such as calf and ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Any dentist who ... challenges of the current process. Many of them do not ... the technical difficulties and high laboratory costs involved. And those ... offer it at such a high cost that the majority ... Dr. Parsa Zadeh , founder of Dental ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: RO, ... clearance for its Elecsys BRAHMS PCT (procalcitonin) assay as ... or septic shock. With this clearance, Roche is the ... fully integrated solution for sepsis risk assessment and management. ... bacterial infection and PCT levels in blood can aid ...
(Date:6/23/2016)... -- Research and Markets has announced the addition ... to their offering. The ... commercial environment for MedImmune to enter. The US ageing population ... to drive considerable growth for effective anti-influenza medications. The introduction ... considerably, but development is still in its infancy. ...
Breaking Medicine Technology: