Navigation Links
Standard Dose of Blood Thinner May Not Be Best for All Patients
Date:11/6/2012

TUESDAY, Nov. 6 (HealthDay News) -- Seventy-five percent of patients taking the widely used blood thinners clopidogrel (Plavix) and prasugrel (Effient) are getting the incorrect dose and could be at risk for serious problems such as uncontrolled bleeding or blood clots, a new study contends.

Millions of Americans with coronary artery disease take the drugs to prevent blood clots that could cause a heart attack or stroke. Guidelines recommend that all patients take the same standardized dose, but that dose is not effective for all patients, according to researchers at the Intermountain Medical Center Heart Institute in Salt Lake City.

The researchers looked at more than 500 patients and found that half of patients taking Plavix were getting too little of the drug to most effectively prevent blood clots, while a quarter were getting too much. Only a quarter were receiving an appropriate dose.

Among patients taking Effient, half were taking too much of the drug, which could lead to dangerous bleeding. A quarter were taking too little of the drug and a quarter were taking the appropriate dose.

The researchers also concluded that indicators like age, gender, cholesterol levels and history of heart problems were not good predictors for how a patient would react to the blood thinners.

"There's a sweet spot, an appropriate range for each patient. But we found that not many people are falling into that range," cardiac researcher Dr. Brent Muhlestein said in an institute news release.

"We showed that by performing a simple blood test to see whether or not the blood is clotting properly, we can determine whether patients are getting an appropriate, individualized dose of the medications," he added. "The test is easy to perform, but not widely used."

The study was presented Tuesday at the American Heart Association annual meeting in Los Angeles. The data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. Agency for Healthcare Research and Quality has more about blood thinners.

-- Robert Preidt

SOURCE: Intermountain Medical Center Heart Institute, news release, Nov. 6, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New research suggests standardized booster seat laws could save lives of children
2. Settings standards for research into Rett syndrome
3. Standard chemotherapy provides higher survival rate than experimental in lung cancer patients
4. First validated method for analyzing flavanols and procyanidins in cocoa products could help scientists and the industry in standardized reporting
5. Gold standards of success defined for AF ablation
6. CRT consensus set to standardize and improve care for patients worldwide
7. New device to remove stroke-causing blood clots proves better than standard tool
8. Alcohol advertising standards violations most common in magazines with youthful audiences
9. Standard radiation therapy dose provides pain relief for painful heel spurs
10. New technology represents next-generation tool for detecting substandard and counterfeit medicines
11. Adding Vitamin B12 to Standard Drugs Might Help Fight Hepatitis C
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Standard Dose of Blood Thinner May Not Be Best for All Patients
(Date:1/17/2017)... ... January 17, 2017 , ... Anesthesia Progress – Everyone wants less ... best drug option for each patient. Dentists have several general anesthesia alternatives and finding ... Researchers from the Tokyo Dental College in Tokyo, Japan wanted to find out which ...
(Date:1/17/2017)... ... January 17, 2017 , ... Today, to ... Carol Francis re-releases powerfully uplifting interview with medical expert and prolific author, Dr. ... and pass through tough times, Dr. Bernie Siegel energizes listeners to live life ...
(Date:1/17/2017)... Grove Village, IL (PRWEB) , ... January 17, ... ... for musicians and music enthusiasts at the National Association of Music Merchants (NAMM) ... January 19 – 22, 2017. , Etymotic’s ER•4® has long been the gold ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... for EMS and firefighting professionals, has released four new continuing education courses as ... are taught live in an online classroom and meet the requirements of the ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... with Sigfox in the U.S.A. to offer Internet of Things (IoT) ... offerings on large-scale environmental sensor deployments such as monitoring solutions used to detect ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... NEW YORK , Jan. 17, 2017 ... a CAGR of around 8.2% over the next decade ... the prominent trends that the market is witnessing include ... portable nebulizers, recent technological advancements in nebulizer products and ... on device type the market is categorized into pneumatic ...
(Date:1/17/2017)... -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) today announced ... Phase 3 clinical trial comparing the efficacy and safety ... prevention of hepatic veno-occlusive disease (VOD) in adult and ... are at high risk or at very high risk ... conducted across approximately 100 medical centers in ...
(Date:1/17/2017)... 17, 2017 According to a new market research report "Neural ... Visualization Software), Vertical, and Region - Global Forecast to 2021" published by MarketsandMarkets, ... Billion by 2021, at a Compound Annual Growth Rate (CAGR) of 33.2%. ... ... MarketsandMarkets Logo ...
Breaking Medicine Technology: