Navigation Links
St. Jude Children's Research Hospital launches data website for genome project
Date:1/11/2012

St. Jude Children's Research Hospital has launched a freely available website for published research results from the St. Jude Children's Research Hospital Washington University Pediatric Cancer Genome Project (PCGP). The PCGP is the largest effort to date aimed at sequencing the entire genomes of both normal and cancer cells from pediatric cancer patients, comparing differences in the DNA to identify genetic mistakes that lead to childhood cancers.

Titled "Explore," the website is designed to expand access to high-quality genomic data related to pediatric cancers, accelerate discovery and hypothesis testing, and provide comprehensive visualizations of the data. Explore is also designed to make it easier for clinical and basic researchers to search published results from the PCGP.

Launched in January 2010 in collaboration with Washington University School of Medicine in St. Louis, the PCGP is focused on sequencing the entire genomes of both normal and cancer cells from 600 childhood cancer patients in the first three years, comparing differences in the DNA to identify genetics mistakes that lead to cancer. No one had sequenced a complete pediatric cancer genome prior to the PCGP, which has sequenced more than 250 sets to date. This work has already led to discoveries featured in two recent papers published in Nature reporting significant advances in understanding the genetic basis of an aggressive subtype of acute lymphoblastic leukemia (ALL), known as early T-cell precursor ALL or ETP-ALL, and in retinoblastoma.

"Explore allows researchers to access the genome project's unique, published data specific to pediatric cancers and to make discoveries of their own," said James Downing, M.D., deputy director and scientific director at St. Jude. "We want to be a catalyst for the field and accelerate progress with the research gleaned from the genome project."

Rich in visual features, Explore allows users to get an overview of the genome project's progress; access to specific diseases; summaries of current discoveries; links to associated publications; views of single-patient genome data to disease levels and more. An online workbench of sorts, Explore will also provide information on what other cancers are currently under investigation by the PCGP.

"The entire research community will now be able to mine this rich set of findings," said Clayton Naeve, Ph.D., chief information officer at St. Jude. "Access to the genome project's user-friendly data website is a step in that direction."


'/>"/>

Contact: Carrie Strehlau
media@stjude.org
901-595-2295
St. Jude Children's Research Hospital
Source:Eurekalert

Related medicine news :

1. Researcher at Childrens Hospital LA discovers way to overcome radiation resistance in leukemia
2. Parents Want Electronic Access to Their Childrens Docs: Survey
3. Lab-made tissue picks up the slack of Petri dishes in cancer research
4. Omega-3 fatty acids could prevent and treat nerve damage, research suggests
5. Groundbreaking cancer research receives massive funding boost
6. Kessler Foundation and USC collaborate on clinical virtual reality for disability research
7. Hopkins researchers find Google Flu Trends a powerful early warning system for emergency departments
8. Researchers Look at Genomes of Nonsmokers With Lung Cancer
9. KalVista and JDRF form research partnership for novel treatment of diabetic eye disease
10. Researchers discover new culprit in atherosclerosis
11. TGen researchers map potential genetic origins, pathways of lung cancer in nonsmokers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... CT (PRWEB) , ... February 22, 2017 , ... The ... and the 2017 Forecast —on Thursday, February 23, 2017, at 1:00 PM ET. A ... webinar is part of the Interactive Webinar Series. , If you want to find ...
(Date:2/22/2017)... ... February 22, 2017 , ... FPS is a nonprofit mental ... Established in 1977, our organization was at the forefront in working with veterans ... life were evident and served as the catalyst for the establishing the agency. ...
(Date:2/22/2017)... Wis (PRWEB) , ... February 22, 2017 , ... ... a category by itself - the Vector™ Series Multi-Cook Oven offers up to ... oven chamber, featuring exclusive Structured Air Technology™ for unmatched evenness in cooking. Alto-Shaam ...
(Date:2/21/2017)... ... February 21, 2017 , ... Robins & Morton ... Durant, Oklahoma, on Feb. 21. , The celebration began with a ribbon cutting ... employees, the construction team and tribal leadership. , Choctaw Nation Durant Regional ...
(Date:2/21/2017)... , ... February 21, 2017 , ... As recently as ... according to the American Society of Plastic Surgeons. Some patients want to make a ... of their nose and improve their breathing ability. The team at usrhinoplasty.org ...
Breaking Medicine News(10 mins):
(Date:2/22/2017)...  Soligenix, Inc. (Nasdaq: SNGX ) ... focused on developing and commercializing products to treat ... need, announced today that its proprietary formulation of ... for the treatment of psoriasis. The issued patent, ... skin conditions, complements the method of treatment claims ...
(Date:2/21/2017)... NEW YORK , Feb. 21, 2017 /PRNewswire/ ... the full report: http://www.reportlinker.com/p04711309-summary/view-report.html ... current as well as future prospects of the ... companies and intermediaries engaged in the manufacture and ... as well as new entrants planning to enter ...
(Date:2/21/2017)... , Feb. 21, 2017 The global infusion ... of 6.0% from 2016 to 2021, to reach USD ... 2016. Increasing prevalence of chronic diseases along with increasing ... reduce hospital expenditure, steady increase in surgical procedural volumes, ... are some of the key factors driving the growth ...
Breaking Medicine Technology: