Navigation Links
St. John's wort collection mined for its medicinal value
Date:3/30/2010

This press release is available in Spanish.

A unique collection of St. John's wort (Hypericum) curated by Agricultural Research Service (ARS) scientists in Ames, Iowa, is providing university collaborators with genetically diverse, well-documented sources of this herb to use in studies examining its medicinal potential.

In collaboration with Mark Widrlechner, a horticulturist with the ARS crop genebank at the North Central Regional Plant Introduction Station in Ames, scientists from the Center for Research on Botanical Dietary Supplements (CRBDS) are screening 180 germplasm accessions of St. John's wort for biologically active compounds. Some may be worth evaluating further in clinical trials for their potential to combat viral infections, reduce inflammation or improve digestive health.

Established in 1948, the ARS Ames crop genebank curates more than 50,000 accessions of ornamental plants, maize, oilseeds, vegetables and other crops, and provides them to researchers for many applications. Accessions with medicinal or nutraceutical value include Echinacea (purple coneflower), Hypericum, Prunella (self-heal) and Actaea racemosa (black cohosh). ARS horticulturist Luping Qu curates the collection and Widrlechner coordinates its use for research at CRBDS, one of six Botanical Research Centers funded by the National Institutes of Health from 2005-2010.

The Hypericum collection at Ames was started in the 1990s and today encompasses about 60 species collected from around the world. This diversity has enabled investigations of genetic, environmental and developmental factors affecting the quantity and quality of bioactive compounds, as well as their modes of action.

Of particular interest is how these compounds interact, and whether those interactions are critical to human health benefits. In a recent issue of Pharmaceutical Biology, researchers noted that combinations of four compounds from St. John's wort (amentoflavone, chlorogenic acid, pseudohypericin and quercetin) were more effective at reducing inflammation in mouse macrophage assays than when each was used alone.


'/>"/>

Contact: Jan Suszkiw
Jan.Suszkiw@ars.usda.gov
301-504-1630
United States Department of Agriculture-Research, Education, and Economics
Source:Eurekalert

Related medicine news :

1. Johns Hopkins Health System Acquires Imorgon Ultrasound PACS Product
2. SC Johnson and Bill & Melinda Gates Foundation Unite to Combat Malaria
3. Johns Hopkins Launches “Energy Policy and Climate” Master's Degree
4. Robert Wood Johnson Foundation Launches New Scholars, Fellows & Leadership Programs Web Site
5. Johnson & Johnson to Participate in RBC Capital Markets Health Care Conference
6. AADR awards the 2010 Jack Hein Public Service Award to David C. Johnsen
7. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
8. Longtime Quality Assurance Executive Randy Johnson Joins White Pine Systems as Vice President of Product Services
9. Protecting patients: Study shows that Johns Hopkins flu vaccination rates twice national average
10. Jimmy Johnson Will Step Into Role as Honorary Crew Chief for ExtenZe Racing at Daytona
11. PJ Johnson Joins StatCom as Enterprise VP, Southeast Region
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... , ... February 26, 2017 , ... ... for entries to the 7th Edition of International Social Design Awards. , ... Professionals, Product Designers, System Designers, Governments and Institutions worldwide with realized projects and ...
(Date:2/26/2017)... Philadelphia, PA (PRWEB) , ... February 26, 2017 , ... ... products and services with Pay-For-Performance B2B Marketing. B2B Sellers will now only pay for ... , Robert Hennessey, the founder of IndustryArchive.Org, said, “Given the new reality that B2B ...
(Date:2/26/2017)... , ... February 26, 2017 , ... ... disease (PD) in persons with a specific LRRK2 mutation, according to a study ... Previous studies have provided evidence of a link between pesticides and incidence of ...
(Date:2/24/2017)... ... February 24, 2017 , ... Only two months after the official ... (ILTM) show in Cannes (France), XO Private has initiated a second print-run of its ... measures almost a metre across when open, weighs in at more than six kilos, ...
(Date:2/24/2017)... ... February 24, 2017 , ... The Smart Machine Age is ... University predict that 47 percent of all jobs in the United States may be ... “successful.” The day of the aggressive know-it-all who steamrolls over colleagues is drawing to ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... Following receiving CE Marking in ... s AMAR is a major milestone for the country where the ... ound care market in Israel ... for inclusion in the National Health Basket , Israel ... E-QURE Corp. (OTCQB: EQUR), a leader in medical devices for the treatment ...
(Date:2/24/2017)... and Markets has announced the addition of the "Hemophilia Drugs Price ... ... Analysis and Strategies - 2016, provides drug pricing data and benchmarks in ... What are the key drugs marketed for Hemophilia ... market? What are the unit prices and annual treatment ...
(Date:2/24/2017)... 24, 2017 Medical information groups within ... their self-service capabilities to manage inquiries from external ... New research from consulting leader Best Practices, ... self-service website portals where HCPs can sign on ... of many findings to emerge from the new ...
Breaking Medicine Technology: