Navigation Links
St. Gallen consensus 2009: A radically different approach to treating early breast cancer
Date:6/17/2009

cerning treatment of women with early breast cancer. While the 2009 consensus maintains an emphasis on targeting adjuvant systemic therapies according to subgroups defined by predictive markers, it further refines the treatment algorithm by identifying 'thresholds for indication' of each type of systemic treatment modality (endocrine therapy, anti-HER2 therapy, chemotherapy) based on criteria specific to each modality. We expect the refined algorithm to change clinical practice because it clarifies the indications for each treatment modality available today."

Early breast cancer is defined as breast cancer that is confined to the breast, with or without axillary lymph node involvement, and which is easily removable by surgery. However, there are many different types, some of which carry a much higher risk of recurrence and metastases than others.

Therefore, the report emphasises the importance of identifying which type of breast cancer a patient has and which treatment, or combination of treatments, are most likely to be successful.

For instance, the panel recommends the inclusion of adjuvant endocrine therapy for most patients whose tumours show evidence of any detectable oestrogen receptor. Anti-HER2 therapy such as trastuzumab (Herceptin) is recommended for almost all patients with HER2-positive disease. The indication for use of adjuvant chemotherapy is more complex. Chemotherapy should be the mainstay of treatment for patients with triple-negative disease and conventionally is used before or concurrently with trastuzumab for patients with HER2 positive disease, while its use is less clear-cut for patients with ER-positive, HER2-negative disease.

The increasing use of genetic profiling using microarrays (gene chip technology) is expected to help in such cases where treatment decisions are more difficult. Another of the authors, Professor Aron Goldhirsch (Professor of Medical Oncology, Director of the Department of Medicine, Eu
'/>"/>

Contact: Emma Mason
wordmason@mac.com
44-771-129-6986
European Society for Medical Oncology
Source:Eurekalert

2

GOOD

Page: 1 2 3

Related medicine news :

1. Businesses, Unions, Veteran Party Leaders Unite Behind Bipartisan, Consensus Approach to Health Care Reform
2. Experts reach consensus on diagnosis and treatment of bleeding disorders in women
3. Expert consensus on catheter ablation of ventricular arrhythmias
4. SCAI Releases Consensus Statement on Length of Stay Following Elective Percutaneous Coronary Intervention
5. Expose on Crimes Against Humanity as Perpetrated by the Gerontological Elite Asks Is Consensus in Anti-Aging Medical Intervention An Elusive Expectation or A Realistic Goal?
6. GPhA Statement on the Introduction of the Bipartisan Senate Biogenerics Consensus Bill: Promoting Innovation and Access to Life-Saving Medicine Act
7. International Panel of Experts Gather for Roundtable Consensus Regarding Multiple Myeloma Related Disease
8. National End-of-Life Organizations Release Consensus Statement on Hospice, the Medicare Hospice Benefit, and Key Issues for the Future
9. Experts at American Society for Reproductive Medicine (ASRM) Satellite Symposium Reach Consensus: Better Intimacy = Better Overall Well-Being
10. Europe seeks consensus over living wills
11. NQF Endorses Consensus Standards to Reduce Waste and Promote Safe and Effective Use of Imaging Procedures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/16/2009)... -- For wounded U.S. servicemen and women ... D.C., the holidays can be a particularly difficult time. ... rely more than ever on the healing power of ... home just got easier for Walter Reed patients as ... will provide hundreds of minutes of holiday talk time ...
(Date:12/16/2009)... second, possibly deadly, attack is long-term goal, researchers say ... have developed a tool to predict whether a patient ... a first stroke. , "This is an important new ... a second stroke soon after a first stroke are ... Hakan Ay, of Massachusetts General Hospital and Harvard Medical ...
(Date:12/16/2009)... help ease health and environmental concerns about the emerging ... changing the behavior of nanoparticles in municipal sewage treatment ... study was published in ACS, journal Environmental Science ... Centre for Ecology and Hydrology and colleagues note that ... particles less than 1/1000th the width of a ...
(Date:12/16/2009)... Coalition Urges Lawmakers to Ensure and Encourage Access to Quality, Cost-Effective ... ... -- For months, members of Congress have debated the best ways ... part of health care reform. An important part of the ... full range of health care providers besides doctors of medicine (MDs) ...
(Date:12/16/2009)... Therapy or NSRTSM is found very effective in the alleviation ... asthma, migraines, chronic fatigue and a wide array of skin ... using this holistic therapy including over 50 branded BioVeda Health ... ... MN (Vocus) December 14, 2009 -- BioVeda Health and Wellness ...
Breaking Medicine News(10 mins):Health News:Verizon Wireless Donates $10,000 in Long-Distance Calling Cards to Soldiers at Walter Reed Hospital 2Health News:New Stroke Tool May Predict Early Recurrence 2Health News:Behavior modification could ease concerns about nanoparticles 2Health News:Coalition for Patients' Rights: Access to Broad Range of Health Care Providers Critical to Lowering Costs 2Health News:Coalition for Patients' Rights: Access to Broad Range of Health Care Providers Critical to Lowering Costs 3Health News:Coalition for Patients' Rights: Access to Broad Range of Health Care Providers Critical to Lowering Costs 4Health News:Coalition for Patients' Rights: Access to Broad Range of Health Care Providers Critical to Lowering Costs 5Health News:BioVeda Health and Wellness Center of Chanhassen, MN Announces Its Grand Opening 2Health News:BioVeda Health and Wellness Center of Chanhassen, MN Announces Its Grand Opening 3Health News:BioVeda Health and Wellness Center of Chanhassen, MN Announces Its Grand Opening 4Health News:BioVeda Health and Wellness Center of Chanhassen, MN Announces Its Grand Opening 5
... Today, ReCellular announced a new,cell-phone recycling campaign to ... is to raise a minimum of $50,000 for the ... "In 1991, we started with a simple mission ... and environmentally responsible," says Chuck,Newman, founder and CEO of ...
... an urgent need for greater coordination and harmonisation between ... from large numbers of people that can be used ... To enable this, there should also be closer coordination ... as increased and sustained funding for biobanks. This will ...
... University] Magnetic resonance imaging (MRI) can be a ... body without resorting to surgery. MRI scans use pulses ... identify different types of tissue in the body, distinguishing ... , Scientists have found that magnetic nanoparticles can be ...
... for Storage and to Advance VSEL Research, NEW ... ),which is pioneering the pre-disease collection, processing and long-term,storage ... announced that,it has signed a collection center agreement with ... Robin Smith, MD MBA, NeoStem,s Chairman and Chief ...
... CARLSBAD, Calif., May 27 Isis,Pharmaceuticals, Inc. (Nasdaq: ... receive,$4.6 million dollars from Alnylam Pharmaceuticals, Inc. (Nasdaq: ... fees in the recently announced transaction,between Takeda Pharmaceutical ... potential to receive portions of future milestone and ...
... save time and money accepting automatic ... direct from resident bank accounts, PORTLAND, Ore., ... added PaySimple, the leading provider of on-demand electronic ... help simplify resident billing,and collection for assisted living, ...
Other Medicine News:Health News:ReCellular and American Red Cross Announce Cell-Phone Recycling Campaign 2Health News:ReCellular and American Red Cross Announce Cell-Phone Recycling Campaign 3Health News:Europe's biobanks need urgent coordination -- scientists say 2Health News:Brown chemists create cancer-detecting nanoparticles 2Health News:NeoStem Signs Stem Cell Collection Agreement With University of Louisville Hospital 2Health News:NeoStem Signs Stem Cell Collection Agreement With University of Louisville Hospital 3Health News:Isis to Receive $4.6 Million From Alnylam 2Health News:Isis to Receive $4.6 Million From Alnylam 3Health News:Vigilan Offers PaySimple to Simplify Resident Billing and Collection 2
(Date:12/16/2009)... 16 Wound Management Technologies, Inc. ... provider of specialty medical products, announced today ... moving toward productization of its patented orthopedic ... anticipates products to be introduced in Q3 ... be a multi-billion dollar international market. ,, ...
(Date:12/16/2009)... (OTC Bulletin Board: HEWA) an online U.S. mail-order pharmacy, ... per annum short term debt financing. The structure ... $500,000, with accrued interest and principal repayable in one ... and principal repayable in one year from its funding, ... any calendar month prior to December 15, 2010. ...
(Date:12/16/2009)... -- International, well-known,scientific experts were surprised ... mg/day),data presented as "extremely promising."[1] More ... clinicians critically reviewed these data.,These experts ... lipid-modifying,treatments, fenofibrate and bezafibrate, in treating ... patients with metabolic syndrome,and type 2 ...
Breaking Medicine Technology:Wound Management Technologies, Inc. Targets Multi-Billion Dollar Biomaterials Market; Releases Update on Resorbable Orthopedics 2Wound Management Technologies, Inc. Targets Multi-Billion Dollar Biomaterials Market; Releases Update on Resorbable Orthopedics 3HealthWarehouse.com, Inc. Secures $1 Million in Debt Financing 2International, Well-Known Scientific Experts Say That New GFT505 Data Unlikely to Have the Potential to Affect the Established Role of Generic Fenofibrate and Bezafibrate in Managing Atherogenic Dyslipidemia 2International, Well-Known Scientific Experts Say That New GFT505 Data Unlikely to Have the Potential to Affect the Established Role of Generic Fenofibrate and Bezafibrate in Managing Atherogenic Dyslipidemia 3Midwest Mobile Dog Heart Health Tour to Provide Free Heart Examinations 4861 1Midwest Mobile Dog Heart Health Tour to Provide Free Heart Examinations 4861 2Midwest Mobile Dog Heart Health Tour to Provide Free Heart Examinations 4861 3Severe breathing disorders during sleep are associated with an increased risk of dying 9606 1Severe breathing disorders during sleep are associated with an increased risk of dying 9606 2Disney Donates 24100 000 to Red Cross Catastrophic Disaster Planning 54690 1Disney Donates 24100 000 to Red Cross Catastrophic Disaster Planning 54690 2
... Dr. Gregory Ellison, Director of Advanced Medical Center, Licensed to ... ... a critical crisis,of methamphetamine use, Dr. Gregory Ellison, Director of Advanced ... high success rates and is performed on an out-patient (versus,in-patient) basis ...
... Extensive Data to be Presented at the Upcoming ... Further to the,press release published on 9 April, ... elements of the clinical programme with,intravenous iclaprim in ... on ASSIST-1 has been presented at last year,s ...
Other Medicine Technology:Arizona Doctor Offers New Addiction Drug Treatment for Meth Addicts Showing More Than 60% Success Rate 2Arizona Doctor Offers New Addiction Drug Treatment for Meth Addicts Showing More Than 60% Success Rate 3Arpida Provides Further Comments on the Pivotal Phase III Trials 2Arpida Provides Further Comments on the Pivotal Phase III Trials 3Arpida Provides Further Comments on the Pivotal Phase III Trials 4
Colloidal Gold Conjugated, Streptavidin - 50 OD...
Colloidal Gold Conjugated, Goat anti-rabbit IgG (H&L) - 12 OD...
Colloidal Gold Conjugated, Goat anti-mouse IgG (H&L) - 50 OD...
Colloidal Gold Conjugated, Goat anti-human IgG (H&L) - 12 OD...
Medicine Products: