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Sprouts? Supplements? Team them up to boost broccoli's cancer-fighting power
Date:1/27/2011

URBANA A new University of Illinois study provides convincing evidence that the way you prepare and consume your broccoli matters, and also suggests that teaming broccoli with broccoli sprouts may make the vegetable's anti-cancer effect almost twice as powerful.

"Broccoli, prepared correctly, is an extremely potent cancer-fighting agentthree to five servings a week are enough to have an effect. To get broccoli's benefits, though, the enzyme myrosinase has to be present; if it's not there, sulforaphane, broccoli's cancer-preventive and anti-inflammatory component, doesn't form," said Elizabeth Jeffery, a U of I professor of nutrition.

According to Jeffery, many people destroy myrosinase by overcooking their broccoli. And health-conscious consumers who use broccoli powder supplements in recipes to boost their nutrition are also missing out. These supplements often do not contain this necessary enzyme, she said.

"There is a way to boost that powder's effectiveness, though. Broccoli sprouts contain myrosinase in abundance. And broccoli powder often contains the precursor to sulforaphane without the enzyme that would boost its healthful benefits," said Jenna Cramer, co-author of the study.

The scientists hypothesized that myrosinase from the sprouts would enhance sulforaphane formation and absorption from the broccoli powder if the two were eaten together.

In a small pilot study, they recruited four healthy men who ate meals that contained broccoli sprouts alone, broccoli powder alone, or a combination of the two. The researchers then measured levels of sulforaphane metabolites in the mens' blood and urine after feeding.

"We were looking at biomarkersplasma and urine levelsthat are associated with cancer prevention," Cramer said.

Three hours after feeding, a definite synergistic effect was noted between the powder and the sprouts.

"There was almost a twofold increase in sulforaphane absorpt
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Contact: Phyllis Picklesimer
p-pickle@illinois.edu
217-244-2827
University of Illinois College of Agricultural, Consumer and Environmental Sciences
Source:Eurekalert

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