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Split-dose preparation for colonoscopy increases precancerous polyp detection rates
Date:9/19/2012

OAK BROOK, Ill. September 19, 2012 A new study from researchers at the Mayo Clinic Arizona showed that system-wide implementation of a split-dose preparation as the primary choice for colonoscopy significantly improved both polyp detection rates and adenoma (precancerous polyp) detection rates, overall quality of the preparation, and colonoscopy completion rates. The study appears in the September issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE).

Colorectal cancer develops slowly, therefore screening for the disease is especially important. Colonoscopy screening allows for the detection and removal of precancerous polyps (small growths in the colon) during the same exam and before the polyps turn into cancer. One of the most important steps in colonoscopy is patient bowel preparation. Adequate preparation ensures that the colon is thoroughly cleaned before the exam so that the physician can clearly see the entire colon to look for abnormalities, such as colon polyps, during the procedure. Cleansing the colon before a colonoscopy is called bowel preparation, or "prep." It involves taking medication that causes diarrhea, emptying the colon. The medication is taken by mouth, and comes in liquid or tablet form. Patients also need to change what they eat during the day or two before the colonoscopy.

A good-quality bowel preparation is essential for colonoscopy to be effective. Inadequate bowel preparation can result in incomplete procedures, missed lesions, higher complication rates, and increased costs resulting from repeated procedures. The polyethylene glycol (PEG) solution is commonly used as a cleansing bowel preparation because it is safe and does not cause major fluid and electrolyte shifts. A major disadvantage, however, is the large volume required to be taken over a short time that may result in patient intolerance and poor compl
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Contact: Anne Brownsey
abrownsey@asge.org
630-570-5635
American Society for Gastrointestinal Endoscopy
Source:Eurekalert

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