Navigation Links
Spleen Cells Tied to Damage of Spinal Cord Injury in Animal Study
Date:11/18/2010

THURSDAY, Nov. 18 (HealthDay News) -- The spleen may be a major source of cells that cause inflammation and exacerbate the damage at the site of a spinal cord injury, a new animal study suggests.

The findings could change the focus of efforts to find new treatments for spinal cord injuries, researchers said.

While most spinal cord injury research has focused on bone marrow as the source of these inflammation-causing cells called macrophages, some studies have suggested that another source may be the spleen, which helps the body fight infections.

This study, conducted by researchers from Ohio State University, compared two groups of mice with spinal cord injuries: mice that had spleens and another group whose spleens were removed before the injury. Two weeks after spinal cord injury, macrophage levels were 20 percent lower in the injured mice without spleens.

"The spleen is releasing cells that are traveling to the injury site, and it's a significant number of cells," study leader Alicia Hawthorne, a postdoctoral researcher in neuroscience at Ohio State University, said in a university news release.

"If we could target the spleen to decrease these cells or change their properties and make them less destructive, this might help promote the repair process as opposed to letting them cause inflammation or further damage to neurons," she added.

The study was presented at the recent annual meeting of the Society for Neuroscience. Because it was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about spinal cord injuries.

-- Robert Preidt

SOURCE: Ohio State University, news release, Nov. 16, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Tiny Trojan horses attack brain cancer cells
2. Mysterious cells may play role in ALS
3. Study Hints at Stem Cells From Belly Fat as Treatment for Heart Attack
4. How do neural stem cells decide what to be -- and when?
5. Mathematical model of the life cycle of red blood cells may predict risk of anemia
6. Rogue gene hijacks stem cells to jumpstart human cancer
7. Burning pain and itching governed by same nerve cells
8. Pitt study finds NSAIDs cause stem cells to self-destruct, preventing colon cancer
9. Plant stem cells could be fruitful source of low-cost cancer drug
10. Mount Sinai researchers discover origin of immune cells in the brain
11. Gene identified that prevents stem cells from turning cancerous
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Spleen Cells Tied to Damage of Spinal Cord Injury in Animal Study
(Date:6/26/2016)... PLAINSBORO, N.J. (PRWEB) , ... June 27, 2016 , ... ... same sources, yet in many ways they remain in the eye of the beholder, ... Oncology (EBO), a publication of The American Journal of Managed Care. For the full ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned ... developed to enhance the health of felines. The formula is all-natural and is made ... in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts ... applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention ... health care topics including advance care planning, healthcare costs and patient and family ...
(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin ... injury. Recently, he has implemented orthobiologic procedures as a method for treating his ... of the first doctors to perform the treatment. Orthobiologics are substances that orthopaedic ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Medical Market Analysis 2016 - Forecast to 2022" report ... The report contains up to date financial data derived from ... of major trends with potential impact on the market during ... market segmentation which comprises of sub markets, regional and country ...
(Date:6/23/2016)... Research and Markets has announced the addition of the ... offering. The current unmet ... for MedImmune to enter. The US ageing population creates a ... considerable growth for effective anti-influenza medications. The introduction of a ... development is still in its infancy. Key ...
(Date:6/23/2016)... June 23, 2016 , , ... July 7, 2016 , , , , LOCATION: , , ... , , , EXPERT PANELISTS:  , , , Frost & ... Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, ... The global pharmaceutical industry is witnessing an exceptional era. Several new ...
Breaking Medicine Technology: