Navigation Links
Spleen Cells Tied to Damage of Spinal Cord Injury in Animal Study
Date:11/18/2010

THURSDAY, Nov. 18 (HealthDay News) -- The spleen may be a major source of cells that cause inflammation and exacerbate the damage at the site of a spinal cord injury, a new animal study suggests.

The findings could change the focus of efforts to find new treatments for spinal cord injuries, researchers said.

While most spinal cord injury research has focused on bone marrow as the source of these inflammation-causing cells called macrophages, some studies have suggested that another source may be the spleen, which helps the body fight infections.

This study, conducted by researchers from Ohio State University, compared two groups of mice with spinal cord injuries: mice that had spleens and another group whose spleens were removed before the injury. Two weeks after spinal cord injury, macrophage levels were 20 percent lower in the injured mice without spleens.

"The spleen is releasing cells that are traveling to the injury site, and it's a significant number of cells," study leader Alicia Hawthorne, a postdoctoral researcher in neuroscience at Ohio State University, said in a university news release.

"If we could target the spleen to decrease these cells or change their properties and make them less destructive, this might help promote the repair process as opposed to letting them cause inflammation or further damage to neurons," she added.

The study was presented at the recent annual meeting of the Society for Neuroscience. Because it was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about spinal cord injuries.

-- Robert Preidt

SOURCE: Ohio State University, news release, Nov. 16, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Tiny Trojan horses attack brain cancer cells
2. Mysterious cells may play role in ALS
3. Study Hints at Stem Cells From Belly Fat as Treatment for Heart Attack
4. How do neural stem cells decide what to be -- and when?
5. Mathematical model of the life cycle of red blood cells may predict risk of anemia
6. Rogue gene hijacks stem cells to jumpstart human cancer
7. Burning pain and itching governed by same nerve cells
8. Pitt study finds NSAIDs cause stem cells to self-destruct, preventing colon cancer
9. Plant stem cells could be fruitful source of low-cost cancer drug
10. Mount Sinai researchers discover origin of immune cells in the brain
11. Gene identified that prevents stem cells from turning cancerous
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Spleen Cells Tied to Damage of Spinal Cord Injury in Animal Study
(Date:2/27/2017)... ... 27, 2017 , ... It’s no secret that aging causes ... a host of health issues, including urinary incontinence. However, results published in late ... good overall muscle strength in older women, particularly in the abdominal and pelvic ...
(Date:2/27/2017)... ... 2017 , ... Robert E. Burke, MD, PhD, had a successful career as ... life experiences could have led him down a much different path. , In his ... Perseverance and Pediatrics,” Dr. Burke shares a personal account of the tribulations he encountered ...
(Date:2/27/2017)... NEW PORT RICHEY, Fla. (PRWEB) , ... February 27, 2017 , ... ... substance use disorder, but concern for women who become dependent on opioid painkillers has ... 400% among female patients, compared to a 237% increase in fatal overdoses in male ...
(Date:2/27/2017)... Ohio (PRWEB) , ... February 27, 2017 , ... Elisa Guajardo Carothers is not your ... Life” to studying to become a nun. Now, she writes about God, when she isn’t ... “You Know BC and AD, Here is BS! (Before Satan),” she offers a comedic look ...
(Date:2/27/2017)... ... February 27, 2017 , ... This webinar ... analysis as a tool to characterize particle size distributions in the field of ... results and novel scientific findings. It describes methods of optimized and standardized sample ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... , Feb. 27, 2017  RegeneRx Biopharmaceuticals, Inc. ... drug development company focused on tissue protection, repair ... RGN-137, GtreeBNT Co., Ltd., received a positive response ... clinical trial design for RGN-137 to treat epidermolysis ... gel that incorporates Thymosin beta 4 ("Tß4") as ...
(Date:2/27/2017)... NEW YORK , February 27, 2017 ... (PII) celebrates the pharmaceutical companies that are most successful at ... ... question: if you gave the same molecule to two different ... it? Based on systematic, objective analysis of each ...
(Date:2/27/2017)... Leading Countries, Technologies and Companies ... grow at a CAGR of 8.9% from 2016-2021 and CAGR of ... CAGR of 9.1% from 2016 to 2027. The market is estimated ... ... Read on to discover how you can exploit the future ...
Breaking Medicine Technology: