Navigation Links
Spleen Cells Tied to Damage of Spinal Cord Injury in Animal Study
Date:11/18/2010

THURSDAY, Nov. 18 (HealthDay News) -- The spleen may be a major source of cells that cause inflammation and exacerbate the damage at the site of a spinal cord injury, a new animal study suggests.

The findings could change the focus of efforts to find new treatments for spinal cord injuries, researchers said.

While most spinal cord injury research has focused on bone marrow as the source of these inflammation-causing cells called macrophages, some studies have suggested that another source may be the spleen, which helps the body fight infections.

This study, conducted by researchers from Ohio State University, compared two groups of mice with spinal cord injuries: mice that had spleens and another group whose spleens were removed before the injury. Two weeks after spinal cord injury, macrophage levels were 20 percent lower in the injured mice without spleens.

"The spleen is releasing cells that are traveling to the injury site, and it's a significant number of cells," study leader Alicia Hawthorne, a postdoctoral researcher in neuroscience at Ohio State University, said in a university news release.

"If we could target the spleen to decrease these cells or change their properties and make them less destructive, this might help promote the repair process as opposed to letting them cause inflammation or further damage to neurons," she added.

The study was presented at the recent annual meeting of the Society for Neuroscience. Because it was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about spinal cord injuries.

-- Robert Preidt

SOURCE: Ohio State University, news release, Nov. 16, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Tiny Trojan horses attack brain cancer cells
2. Mysterious cells may play role in ALS
3. Study Hints at Stem Cells From Belly Fat as Treatment for Heart Attack
4. How do neural stem cells decide what to be -- and when?
5. Mathematical model of the life cycle of red blood cells may predict risk of anemia
6. Rogue gene hijacks stem cells to jumpstart human cancer
7. Burning pain and itching governed by same nerve cells
8. Pitt study finds NSAIDs cause stem cells to self-destruct, preventing colon cancer
9. Plant stem cells could be fruitful source of low-cost cancer drug
10. Mount Sinai researchers discover origin of immune cells in the brain
11. Gene identified that prevents stem cells from turning cancerous
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Spleen Cells Tied to Damage of Spinal Cord Injury in Animal Study
(Date:2/8/2016)... ... February 08, 2016 , ... Discover the Rocky Mountain region’s longest running and ... companies. Attendees also get to see the most incredible gardens and home improvement ... , at the Colorado Convention Center - 700 14th St. Denver CO, is an ...
(Date:2/8/2016)... Nevada (PRWEB) , ... February 08, 2016 , ... ... RowdMap, Inc., will be speaking on how healthcare companies can use newly released ... manage the health of a population and intervene and capture the value they ...
(Date:2/7/2016)... Clarkston, Metamora, Michigan (PRWEB) , ... February 07, ... ... correct pelvic organ prolapse with the latest techniques and the most minimally invasive ... for pelvic organ prolapse, particularly after menopause. Other risk factors include surgery to ...
(Date:2/6/2016)... ... 06, 2016 , ... FOR INFORMATION: Gayle ... SURGICAL CONFERENCE & EXPO , WHAT:     , This conference is the largest ... nurses in attendance to study the latest evidence-based recommendations and resources for ...
(Date:2/6/2016)... ... February 06, 2016 , ... Research has shown that ... reduce the frequency and level of relapse. , At the 2016 ... Purpose,” will explore the critical tasks of the recovery phase and beyond including ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)...  Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) announced ... and year-end 2015 results after the Nasdaq market closes ... a live conference call and webcast to discuss its ... February 11, 2016 at 4:30 p.m. Eastern Time (1:30 ... http://www.neurocrine.com . --> Participants can access ...
(Date:2/8/2016)... , February 8, 2016 ... market research report "Ablation Technologies Market by Product (Radiofrequency, ... Pain Management, Cosmetic Surgery, Ophthalmology, Gynecology) - Global Forecasts ... global market over the forecast period of 2015 to ... by 2020, at CAGR of 10.5% from 2015 to ...
(Date:2/8/2016)... LEAWOOD, Kan. , Feb. 8, 2016 ... held organization that formerly specialized in the ... facilities, recently announced that it has divided ... Nueterra Capital. While Nueterra Capital will continue ... advisory services, NueHealth will operate a national ...
Breaking Medicine Technology: