Navigation Links
Spinal cord research heads new $10M funding in London, Ontario
Date:5/8/2008

A researcher striving to help patients recover from spinal cord injuries headlines an announcement of more than $10.5 million in funding from the Canadian Institutes of Health Research (CIHR) at The University of Western Ontario and Lawson Health Research Institute.

Scientists believe a lack of cell regeneration after spinal cord injuries can be attributed to the molecular makeup of scar tissue that inhibits nerve growth. Dr. Arthur Brown, a scientist at Robarts Research Institute at Western, received $782,455 from CIHR to study a protein he has identified that may control regeneration in the injured spinal cord. Currently, there are no effective treatments for spinal cord injuries.

Astrocytes the major cell type that produces scars in the injured central nervous system receive a variety of signals after injury and respond by producing scar proteins, including some that inhibit regeneration and others that promote it. Browns group has discovered that a protein called SOX9 promotes the expression of anti-regenerative scar genes and reduces the expression of pro-regenerative ones. This makes SOX9 inhibition a very attractive strategy to encourage regeneration. He hopes to further understand how SOX9 works with other proteins to regulate scar gene expression and to test whether SOX9 inhibition improves regeneration after spinal cord injuries.

With more than 12,000 spinal cord injuries in Canada and the United States annually, these injuries affect not only patients on a personal level, but also the health care system. Approximately 275,000 North Americans live with permanent, serious disabilities due to spinal cord injuries.

It has been estimated that the impact of neurotrauma is one of the single most costly occurrences in Ontarios health system, says Brown. Improving recovery and regeneration after spinal cord injuries will relieve pressure on our healthcare system and, more importantly, produce priceless improvements to the quality of life of these patients. Brown is also a professor in the Departments of Anatomy & Cell Biology and Physiology & Pharmacology at Western's Schulich School of Medicine & Dentistry.

London has developed a stellar reputation for health research and were grateful to the CIHR for their continued support of health-related initiatives across disciplines throughout the city, says Ted Hewitt, Westerns Vice-President (Research & International Relations).

We are proud of the work of all recipients and CIHRs support of our many local researchers is critical in helping us to make a difference in the lives of patients, says Dr. David Hill, Lawsons Scientific Director.


'/>"/>

Contact: Douglas Keddy
dkeddy@uwo.ca
519-661-2111 x87485
University of Western Ontario
Source:Eurekalert

Related medicine news :

1. Cialis Eases Erectile Dysfunction After Spinal Cord Injury
2. Summit on Spinal Muscular Atrophy
3. New Low-Back Pain Guidelines Should Encourage Patients to Utilize Spinal Manipulation
4. Pioneer Surgical Technology Hires New Spinal Franchise Manager
5. Video: Kyphon Supports World Osteoporosis Day on October 20, 2007 to Raise Awareness of Osteoporosis and Spinal Fracture Risk
6. Mayo Clinic clarifies diagnosis for serious blood vessel disease of brain and spinal cord
7. Spinal cord injury expert to be honored by research foundation
8. ArthroCare Releases New SpineWand(R) for Less Invasive Spinal Surgeries
9. Engineers developing new cements to heal spinal fractures
10. Polyanalgesic Consensus Panels New Treatment Guidelines Via Intraspinal Infusion for Severe Chronic Pain
11. Jefferson researchers find stem cells in degenerating spinal discs, potential for repair
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 10, 2016 , ... Ongoing news of the ravages of traumatic brain ... conduct a survey that takes a closer look at cases of TBI being managed ... causes of TBI among the aging population, and identifies the challenges associated with their ...
(Date:2/10/2016)... MI (PRWEB) , ... February 10, 2016 , ... ... Apifiny® across their network of laboratory service centers across the country. Launched ... to aid clinicians in the detection of prostate cancer. Apifiny order volume exceeded 3,000 ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... ... announced that it has been awarded the prestigious Distinguished Emerald Club of the ... program conducted by BoardRoom magazine, one of the most respected trade publications serving ...
(Date:2/10/2016)... ... February 10, 2016 , ... Workrite Ergonomics, who is celebrating ... evolved from humble beginnings to being an internationally recognized leader in their industry. , ... today”, said Charlie Lawrence, President of Workrite. “Workrite recognized the importance of good ...
(Date:2/10/2016)... ... February 09, 2016 , ... ... Face and Body Specialists are delighted to welcome a new addition to their ... Face and Body Specialists as a nurse practitioner performing cosmetic procedures ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... and SAN DIEGO , ... Inc., a global leader in viral gene therapy manufacturing, ... treatments for congestive heart failure and other chronic diseases, ... a scalable manufacturing process and produce cGMP-grade RT-100 (Ad5.hAC6) ... --> --> ...
(Date:2/10/2016)... 2016 Immune Pharmaceuticals Inc. (NASDAQ: IMNP ... it has filed a patent application directed to the ... --> --> The new ... Ceplene (histamine dihydrochloride) in combination with immune checkpoint inhibitors. ... efficacy of Ceplene and IL-2 therapy in patients with ...
(Date:2/10/2016)... Feb. 10, 2016  Oxis International Inc. (OTC/QB: OXIS) ... was described as a "clinical trial triumph" after one ... into complete cancer remission. Daniel Vallera ... Masonic Cancer Center. --> Daniel Vallera ... Masonic Cancer Center. --> An article ...
Breaking Medicine Technology: