New technologies used to repair spinal fractures could soon be helping patients suffering from the bone marrow cancer multiple myeloma.
A research project led by engineers at the University of Leeds will focus on the disease an incurable cancer of the bone marrow that causes destructive lesions in bones and makes them more susceptible to fracture.
The study will analyse whether techniques such as injecting cements into the spine to stabilise the bone, or using plates to fix fractures can be adapted for affected patients.
Although incurable, improvements in treatment mean that patients with multiple myeloma are surviving for longer, with up to a third surviving for at least five years. However, a better prognosis means that secondary symptoms, such as painful bone deterioration, have more time to take effect.
"Our aim is to give people suffering from this disease a better quality of life. If the spine becomes weakened or fractures, patients can do little more than stay in bed and try to deal with the pain," said Professor of Spinal Biomechanics, Richard Hall, who is leading the research at Leeds' Faculty of Engineering. "The majority of multiple myeloma patients are in their sixties or older, but even simple things that we take for granted, such as sitting your grandchild on your knee, can become impossible for them."
The work will combine laboratory experiments with computer modelling to predict the impacts of various treatments on patients.
Professor Hall will be collaborating with researchers at the Sunnybrook Health Sciences Centre, housed at one of Canada's largest hospitals in Toronto, and clinicians from Leeds Teaching Hospitals NHS Trust.
The project team includes Mr Jake Timothy, Consultant Neurosurgeon in Leeds, who has developed an award winning clinical vertebroplasty and kyphoplasty service that can help to fix painful vertebrae and spinal compression fractures associated with osteoporosis. He has seen the dra
|Contact: Profssor Richard Hall|
University of Leeds