Navigation Links
Spider Venom -- The Next Way to Treat Impotence?
Date:9/25/2009

Toxin from the deadly Brazilian wandering spider may improve erections, researchers say

FRIDAY, Sept. 25 (HealthDay News) -- Scientists may have discovered a novel way to treat erectile dysfunction -- using the venom of a deadly spider.

The bite from the Brazilian wandering spider (Phoneutria nigriventer) causes a painful erection that can last for many hours and later lead to impotence, researchers from the United States and Brazil noted.

After isolating the toxin, the researchers radioactively labeled and injected a purified form of the toxin, Tx2-6, into rats that suffered from high blood pressure and severe erectile dysfunction. The investigators then measured the presence of the toxin in the animals' penises and used the toxin to contract and relax strips of penile tissue. Results showed improved levels of nitric oxide, which led to penile relaxation and erections.

The researchers were scheduled to present their work Sept. 24 at the American Heart Association's conference on high blood pressure research in Chicago.

"In Brazil, it's common to have accidents with poisonous animals," explained lead researcher Kenia Pedrosa Nunes, a post-doctoral fellow in physiology at the Medical College of Georgia in Augusta and a native of Brazil. "So, we were aware of this spider's venom. The toxin was able to normalize erections [in rats]."

Brazilian wandering spiders are found throughout Central and South America. They are considered the world's most venomous spider, causing an unknown number of human deaths.

Erectile dysfunction, also known as impotence, has many causes and a growing body of treatments. According to the National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC), erectile dysfunction "can be a total inability to achieve erection, an inconsistent ability to do so, or a tendency to sustain only brief erections." The condition affects as many as 30 million American men at some point in their lives.

For some, the cause is psychological, but for many others, especially older men, erectile dysfunction usually has a physical source, such as diseases including diabetes, injury or side effects of medications, according to the NKUDIC Web site.

In the late 1990s, the launch of the drug Viagra revolutionized treatment of impotence. The drugs Levitra and Cialis followed. All three medications enhance the effects of nitric oxide, a chemical that relaxes smooth muscles in the penis during sexual stimulation and allows increased blood flow.

The spider venom also works to increase nitric oxide levels but through a different mechanism, Nunes said. Scientists are a long way from using the venom as the basis of a new erectile dysfunction medication, but they are hopeful, said Nunes.

"We do need more research," she added. "I'm sure it can be a pharmacological tool that may one day be able to help patients who cannot take Viagra."

One noted researcher expressed interest in Nunes' work.

"The concept that a venom can have an effect on erection is highly plausible," said Dr. Arnold Melman, chief of urology at Montefiore Medical Center in New York City. "This is very interesting and exciting, but also very early."

More information

The U.S. National Kidney and Urologic Diseases Information Clearinghouse has more on erectile dysfunction.



SOURCES: Kenia Pedrosa Nunes, Ph.D., Medical College of Georgia, Augusta; Arnold Melman, M.D., professor, medicine, Albert Einstein College of Medicine, New York City; National Kidney and Urologic Diseases Information Clearinghouse, Bethesda, Md.; American Heart Association, news release, Sept. 24, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Men are Opting to Remove Spider Veins Over Replacing Hair
2. Men are opting to remove spider veins over replacing hair
3. Spiderhosts Custom Programming Helps Central Floridians Get Healthy
4. Maximus Rocks the Doors off Rocketown at Cancer Benefit Concert Featuring the Pink Spiders, The Running and SupreX
5. Spiders, frogs and gecko among exciting discoveries found in Papua New Guinea
6. New York City Chiropractor Becomes First In North America to Offer Innovative SpiderTech Tape Therapy
7. Garden of Life Launches Lovely Legs(TM) to Reduce Visible Signs of Varicose and Spider Veins
8. Peptide discovered in scorpion venom may hold key to secretory diseases
9. Penn researchers use honeybee venom toxin to develop a new tool for studying hypertension
10. Scorpion Anti-Venom Speeds Childrens Recovery
11. University of Arizona research on scorpion antivenom published in NEJM
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Spider Venom -- The Next Way to Treat Impotence?
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar ... M.D from the David Geffen School of Medicine at UCLA. He trained in Internal ... complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June ... with. The article goes on to state that individuals are now more comfortable seeking ... common operations such as calf and cheek reduction. The Los Angeles area medical group, ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Conference and Scientific Sessions in Dallas that it will receive two significant new ... the grants came as PHA marked its 25th anniversary by recognizing patients, medical ...
(Date:6/24/2016)... ... ... makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum ... by 2020 and then adjusting it yearly to increase at the same rate as the ... wage floor does not erode again, and make future increases more predictable. , The company ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Grove Investment Group (TGIG), has initiated cultivation and processing operations at its production ... and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Research and Markets has announced the addition of ... report to their offering. ... The World Market for Companion Diagnostics covers the world market ... the report includes the following: , World ... Region (N. America, EU, ROW), 2015-2020 , World IVD ...
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... the "Pharmaceutical Excipients Market by Type (Organic Chemical ... Preservative), Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast ... The global pharmaceutical excipients ... 2021 at a CAGR of 6.1% in the forecast ...
Breaking Medicine Technology: