Navigation Links
Sperm Gene May Cause Men's Longevity Disadvantage
Date:12/2/2009

Mouse study suggests the gene could be linked to life span in males

WEDNESDAY, Dec. 2 (HealthDay News) -- Sperm genes may affect life span in humans and other mammals and could help explain why females tend to live longer than males, Japanese scientists say.

The researchers found that mice created using two female genomes -- bi-maternal mice -- lived an average of 186 days longer than mice created from the normal combination of a male and female genome. The normal life span of the mice used in the study is 600 to 700 days, which means the bi-maternal mice lived about one-third longer than normal.

The difference in life span may be caused by a gene on chromosome 9 associated with post-natal growth, the researchers explained in their report, which is published in the Dec. 2 online edition of the journal Human Reproduction.

"We believe that the most likely reason for the differences in longevity relates to the repression of a gene called Rasgrf1 in the bi-maternal mice. This gene normally expresses from the paternally inherited chromosome and is an imprinted gene on chromosome 9 associated with post-natal growth," study author Tomohiro Kono, of the department of bioscience at Tokyo University of Agriculture, explained in a news release from the journal's publisher.

"Thus far, it's not clear whether Rasgrf1 is definitively associated with mouse longevity, but it is one of the strong candidates for a responsible gene," Kono added.

"We have known for some time that women tend to live longer than men in almost all countries worldwide, and that these sex-related differences in longevity also occur in many other mammalian species. However, the reason for this difference was unclear and, in particular, it was not known whether longevity in mammals was controlled by the genome composition of only one or both parents," Kono stated in the news release.

"The study may give an answer to the fundamental questions: that is, whether longevity in mammals is controlled by the genome composition of only one or both parents, and just maybe, why women are at an advantage over men with regard to the life span," Kono concluded.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases outlines how older adults can stay young at heart.



-- Robert Preidt



SOURCE: Human Reproduction, news release, Dec. 2, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stem Cells Coaxed to Make Precursors to Egg, Sperm
2. Sperm May Play Role in Transmission of HIV
3. Donor Sperm Providers Form New Non-Profit
4. Nations Leading Sperm Bank Opens Branch in New York City
5. Sperm Cell Insights May Aid Stem Cell Research
6. California Cryobank Introduces Celebrity Look-a-Likes for Sperm Donors
7. UB start-up provides innovative digital sperm analysis to infertile couples worldwide
8. Male Fertility Supplement Improves Sperm Quality & Motility in Clinical Study
9. Human sperm created from embryonic stem cells
10. New Study Shows Daily Sex Can Increase Sperm Count
11. Daily sex helps to reduce sperm DNA damage and improve fertility
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that covers ... companies have a waiver for care if the client has a cognitive impairment diagnosis. ... pays for care, is often waived, so the benefits from their insurance start immediately,” ...
(Date:10/13/2017)... Abilene, Texas (PRWEB) , ... October 13, 2017 , ... ... publication this week that explains one of the most popular and least understood books ... seems like cryptic and puzzling descriptions that have baffled scholars for centuries. Many have ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “America On The ... identity. “America On The Brink” is the creation of published author, William Nowers. ... great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... meet the demand of today’s consumer and regulatory authorities worldwide. From Children’s to ... and tested to meet the highest standard. , These products are also: ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information ... we intend to develop to enable prevention of a major side effect of ... loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed on-label ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will host its fiscal ... Friday, November 3, 2017, beginning at 7:00 a.m. (CDT) ... a.m. (CDT) / 9:30 a.m. (EDT). In ... guidance for 2018, Hill-Rom executives will also highlight the ... long-range financial outlook through 2020. ...
(Date:9/25/2017)...   Montrium , an industry leader in ... IQPC Trial Master Files & Inspection Readiness Conference ... Clinical Services has selected eTMF Connect ... EastHORN, a leading European contract research organization (CRO), ... to enable greater collaboration with sponsors, improve compliance ...
(Date:9/22/2017)... -- AVACEN Medical (AVACEN) announced that its CE-Marked AVACEN ... with the widespread pain associated with fibromyalgia in the ... Essex, England commented, "I had difficulty ... sleep at all, tremendous pain, with every movement sending ... AVACEN 100] enough, how this has and is helping ...
Breaking Medicine Technology: