Navigation Links
Sperm Cell Insights May Aid Stem Cell Research
Date:8/6/2009

Scientists spot proteins that help sperm revert to stem cell state

THURSDAY, Aug. 6 (HealthDay News) -- Two proteins that play a major role in reverting adult sperm cells back into stem cells have been identified by U.S. researchers.

A team from Johns Hopkins University School of Medicine in Baltimore genetically altered male fruit flies to reduce the activity of two proteins called Jak and STAT in the testis. The researchers reduced the stem cell population in the flies' testis to zero and found that only 60 percent of testis in the genetically altered flies regained stem cells, compared with 97 percent of testis in normal flies.

"We know now that in the fly testis, interfering with Jak-STAT signaling interferes with the process of dedifferentiation," Erika Matunis, an associate professor of cell biology, said in a university news release.

Dedifferentiation is the redirection of stem cells on the way to becoming sperm cells back to stem cells.

The study, published online this week in the journal Cell Stem Cell, may help in efforts to develop effective stem cell therapies.

The Hopkins researchers now want to determine how Jak and STAT control dedifferentiation.

"We don't know if a cell is just reversing all of the steps to go back to being a stem cell or if it is doing something totally new and different, but we're eager to find out," Matunis said.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



SOURCE: Johns Hopkins Medicine, news release, Aug. 6, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. California Cryobank Introduces Celebrity Look-a-Likes for Sperm Donors
2. UB start-up provides innovative digital sperm analysis to infertile couples worldwide
3. Male Fertility Supplement Improves Sperm Quality & Motility in Clinical Study
4. Human sperm created from embryonic stem cells
5. New Study Shows Daily Sex Can Increase Sperm Count
6. Daily sex helps to reduce sperm DNA damage and improve fertility
7. Fruits and Veggies May Improve Sperm Quality
8. Leading Sperm Bank Expands Fertility Preservation Services to the Big Apple
9. Male Infertility Treatment Boosts Sperm Count
10. Researchers clone key sperm-binding proteins
11. Penn vet researchers identify a critical growth factor that stimulates sperm stem cells to thrive
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Sperm Cell Insights May Aid Stem Cell Research
(Date:7/23/2014)... 2014 A Forever Recovery, an open-ended ... to a great start and gives them a solid ... a new Internet Addiction section of its website at ... learn that Internet addiction is not just as legitimate ... that it’s trapping more and more victims each year ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 Adipic ... which is mainly a high-performance plastic, often referred ... range of materials, depending on the monomers employed. ... the automotive industry and the increasing number of ... adipic acid market share, followed by Europe and ...
(Date:7/23/2014)... 23, 2014 (HealthDay News) -- Children and teens who lose ... death in adulthood, a new study suggests. People who ... 50 percent greater risk of death during the study period ... parent, according to the report. Although the study found ... risk of premature death, it wasn,t designed to prove cause-and-effect. ...
(Date:7/23/2014)... For critically ill patients arriving at the emergency ... sedation and amnesia for rapid, life-saving intubation, despite ... The results of a systematic review of ... regard as a "wonder drug" are published online ... The Effect of Ketamine on Intracranial and Cerebral ...
(Date:7/23/2014)... July 23, 2014 SafeUseNow? ... intervention program developed by Principled Strategies , ... HealthPlan of California . Utilizing SafeUseNow’s patent-pending risk ... risk of misusing and abusing controlled substance drugs, ... addiction among its members. , The agreement with ...
Breaking Medicine News(10 mins):Health News:Latest A Forever Recovery Launches Internet Addiction Section on Website 2Health News:North America Adipic Acid Market is Expected to Reach $1.7 Billion in 2018 - New Report by MicroMarket Monitor 2Health News:North America Adipic Acid Market is Expected to Reach $1.7 Billion in 2018 - New Report by MicroMarket Monitor 3Health News:North America Adipic Acid Market is Expected to Reach $1.7 Billion in 2018 - New Report by MicroMarket Monitor 4Health News:Parent's Death May Raise Risk of Early Death for Grown Children, Study Suggests 2Health News:Ketamine can be a wonder drug for ER patients and their physicians 2Health News:Partnership HealthPlan of California Signs Program Participation Agreement with SafeUseNow 2Health News:Partnership HealthPlan of California Signs Program Participation Agreement with SafeUseNow 3Health News:Partnership HealthPlan of California Signs Program Participation Agreement with SafeUseNow 4
... Ind., Nov. 21 Symmetry Medical Inc. (NYSE: SMA ... device industry and other medical markets, announced today that Brian S. ... Vice President and Chief Financial Officer, are scheduled to present at ... York Palace Hotel on Wednesday, December 3, 2008 at 12:30 p.m. ...
... smoking will receive big prizes during a special on-ice presentation ... Energy Center. The winners,were participants in The QuitCash Challenge, a ... The grand prize winner will ... cards from Gander Mountain. , ...
... study suggests , , FRIDAY, Nov. 21 (HealthDay News) -- The ... of asthma, new research suggests. , Babies born in autumn -- ... have almost a 30 percent increased risk of asthma compared to ... in the first December issue of the American Journal of ...
... Just three days after the,JUPITER trial results were presented ... by the New England Journal of Medicine, an,AlphaDetail survey ... anticipate a 14% increase in the use of drug ... risk patients. , ...
... travel nationwide to,ten top locations for Indoor Cycling / ... of innovative cycling training DVDs. The DVDs utilize,first-person ... selectable vocal coaching from industry experts. Sally Edwards,Ironman ... Matty Reed, US,triathlete champion and Olympian are just a ...
... Draeger Safety, Inc., located in,Pittsburgh PA, and ... products,provider, is countering what it believes are unsubstantiated ... of a patent,infringement on the popular Draeger PSS7000 ... Draeger has a ...
Cached Medicine News:Health News:Lucky Quitters to Receive Big Money in Stop-Smoking Contest 2Health News:Autumn Babies More Prone to Asthma 2Health News:Autumn Babies More Prone to Asthma 3Health News:Physicians Anticipate Higher Prescribing Based on JUPITER Study 2Health News:Global Ride Tours Best 12 Cities for SPINNING(R) or Indoor Cycling 2Health News:Draeger Counters What It Believes Are Unsubstantiated Allegations of Patent Infringement by Sperian 2
(Date:7/23/2014)... -- Lightlake Therapeutics Inc. ("Lightlake") (OTCQB: LLTP), a biopharmaceutical ... in opioid antagonists, announced today that it has ... respect to its naloxone-based opioid overdose reversal nasal ... received an additional commitment from the National Institute ... Institutes of Health ("NIH"), to fund a second ...
(Date:7/23/2014)... July 23, 2014 This September leading clinicians ... Las Vegas for DOCtalk 2014 ... author, forward thinker and private practitioner Dr. David ... to candidly discuss clinical and practice management efficiency and ... a unique opportunity to welcome fresh thinking and join ...
(Date:7/23/2014)... 23, 2014 Global healthcare company ... facing currency headwinds, increased price competition and supply disruptions ... Andrew Witty points out that the company is very ... reason to be confident about long-term prospects as well ... CFO Simon Dingemans adds that ...
Breaking Medicine Technology:Lightlake Therapeutics Inc. Files Investigational New Drug Application For Naloxone Nasal Spray For Reversing Opioid Overdose And Announces A Further Collaboration With The National Institute On Drug Abuse 2Lightlake Therapeutics Inc. Files Investigational New Drug Application For Naloxone Nasal Spray For Reversing Opioid Overdose And Announces A Further Collaboration With The National Institute On Drug Abuse 32014 DOCtalk Registration Now Open 22014 DOCtalk Registration Now Open 3
2 mm wide x 3 mm long, with rounded triangular tip. Angled 45 degrees. Hexagonal handle....
5.5 pointed curved blade. Octagonal handle....
3 mm curved blade. Round handle....
8 mm downcutting Royce blade. Angled shaft. 60 mm from angle to tip....
Medicine Products: