Navigation Links
Sperm Cell Insights May Aid Stem Cell Research
Date:8/6/2009

Scientists spot proteins that help sperm revert to stem cell state

THURSDAY, Aug. 6 (HealthDay News) -- Two proteins that play a major role in reverting adult sperm cells back into stem cells have been identified by U.S. researchers.

A team from Johns Hopkins University School of Medicine in Baltimore genetically altered male fruit flies to reduce the activity of two proteins called Jak and STAT in the testis. The researchers reduced the stem cell population in the flies' testis to zero and found that only 60 percent of testis in the genetically altered flies regained stem cells, compared with 97 percent of testis in normal flies.

"We know now that in the fly testis, interfering with Jak-STAT signaling interferes with the process of dedifferentiation," Erika Matunis, an associate professor of cell biology, said in a university news release.

Dedifferentiation is the redirection of stem cells on the way to becoming sperm cells back to stem cells.

The study, published online this week in the journal Cell Stem Cell, may help in efforts to develop effective stem cell therapies.

The Hopkins researchers now want to determine how Jak and STAT control dedifferentiation.

"We don't know if a cell is just reversing all of the steps to go back to being a stem cell or if it is doing something totally new and different, but we're eager to find out," Matunis said.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



SOURCE: Johns Hopkins Medicine, news release, Aug. 6, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

1

GOOD

Page: 1

Related medicine news :

1. California Cryobank Introduces Celebrity Look-a-Likes for Sperm Donors
2. UB start-up provides innovative digital sperm analysis to infertile couples worldwide
3. Male Fertility Supplement Improves Sperm Quality & Motility in Clinical Study
4. Human sperm created from embryonic stem cells
5. New Study Shows Daily Sex Can Increase Sperm Count
6. Daily sex helps to reduce sperm DNA damage and improve fertility
7. Fruits and Veggies May Improve Sperm Quality
8. Leading Sperm Bank Expands Fertility Preservation Services to the Big Apple
9. Male Infertility Treatment Boosts Sperm Count
10. Researchers clone key sperm-binding proteins
11. Penn vet researchers identify a critical growth factor that stimulates sperm stem cells to thrive
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Sperm Cell Insights May Aid Stem Cell Research
(Date:5/21/2013)... Limited mobility affects people in ways that the ... difficult to walk around, but everyday tasks like getting up ... of medical products made to assist those who need a ... seat. , Raised toilet seats keep users further ... or sit down. They come in a variety of sizes ...
(Date:5/20/2013)... Heritage Woods of Gurnee , ... Illinois, is hosting Breakfast and Bingo at 8:30 a.m. ... located at 3775 Grand Ave. in Gurnee, Illinois, serves ... who need some help to maintain their independence. , ... of bingo," says Tammy Temaner-Rosas, Director of Marketing for ...
(Date:5/20/2013)... When a shopper decides to buy a mattress ... process. Much of the stress and concern people express with ... to expect. Best Mattress Online, a blog about mattress ... their purchase proves smooth. , In the article, titled “ ... readers find helpful tips divided into two sections, questions to ...
(Date:5/20/2013)... Fastcare Miami Beach clinic advises patients to treat ... as if not treated, it may involve the ureter and ... urinary tract infection in itself is not life threatening, if ... pyelonephritis. Women seem to have many more urinary tract infections ... as women after the age of fifty. , As ...
(Date:5/20/2013)... 2013 Eben Pagan's Accelerate ... public creating a frenzy among business owners and ... business training. WealthSpringMarketing.com's Tiffany Hendricks has published a ... exclusive bonus. , "Eben Pagan is a world ... to individuals serious about success," reports Hendricks. "Prior ...
Breaking Medicine News(10 mins):Health News:JustHomeMedical.com Launches Raised Toilet Seats Category 2Health News:Heritage Woods of Gurnee Affordable Assisted Living Community to Host Breakfast and Bingo 2Health News:See What to Expect When You Buy a Mattress Online With Latest Guide From Best Mattress Online 2Health News:Fastcare Advises on How to Prevent a UTI 2Health News:Eben Pagan's Accelerate: Review and Bonus Released By WealthSpringMarketing.com 2
... ... 2009CLEVE to get their $54 marrow cheek-swab kit at no cost. , ... (Vocus) June 15, 2009 -- Two-year-old Eve is one of ... but so far her family has been unable to find one. Thanks to the Gift ...
... NATICK, Mass., June 15 Boston Scientific Corporation (NYSE: ... nine studies involving the Company,s Urology/Gynecology products will be ... Urogynecological Association (IUGA). Presentations will feature Boston Scientific,s ... to treat pelvic floor prolapse and stress urinary incontinence ...
... Unique Intelligent Order Routing allows hospital pharmacies to design ... levels , , ROSEMONT, Ill., June 15 ... Omnicell, Inc., (Nasdaq: OMCL ) a leading ... announced the Omnicell WorkflowRx (TM) 6.0 ...
... Early results from the second series of trials have ... a 4.4 log reduction (99.994%) in Methicillin Resistant Staph Aureus ... medical treatment facilities world wide with the spread of MRSA ... CDC reported (JAMA 2007) that MRSA alone is now associated ...
... considering hair replacement surgery is certain to have lots of questions ... it is called "surgery" causes a person to wonder, "Is Hair ... questions that we have regarding hair replacement ," ... explains, "People want to know that they are going to be ...
... Products announced today the first commercial, plant-based diamine oxidase (DAO). ... reports that this new diamine oxidase is orders of magnitude ... enzyme is available as a lyophilized powder. Price will be ... for test assays to detect spoilage by the presence of ...
Cached Medicine News:Health News:Cleveland Residents Lining up to Help Save a Life with Free Donor Kits 2Health News:Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting 2Health News:Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting 3Health News:Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting 4Health News:Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting 5Health News:Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting 6Health News:Omnicell Boosts Pharmacy Efficiency with Enhanced WorkflowRx(TM) Central Pharmacy Automation Software 2Health News:Omnicell Boosts Pharmacy Efficiency with Enhanced WorkflowRx(TM) Central Pharmacy Automation Software 3Health News:Medizone Announces That Its AsepticSure(TM) Development Program is Reaching Objectives on Two Fronts 2Health News:USHairReplacement.com Provides Wealth of Knowledge to Common Hair Replacement Questions 2
(Date:5/20/2013)... Landauer, Inc. (NYSE: LDR ), ... and monitoring, outsourced medical physics services and high quality ... Directors declared, at its meeting on May 16, 2013, ... for the third quarter of fiscal 2013.  The dividend ... of record on June 7, 2013. About ...
(Date:5/20/2013)... , May 20, 2013   National Community ... Hoey , RPh, MBA issued the following statement ... Associates regarding Medicare Part D "preferred pharmacy" drug ... offering patients the plan,s lowest advertised co-payments: ... Medicare and MedPAC , 16 ...
(Date:5/20/2013)... May 20, 2013  TRACE International today released its ... finding that prosecutions against individuals and government or business ... The GER 2012 is the third in ... enforcement trends. "Although the number of outbound ... laws remained a priority," said Alexandra Wrage ...
Breaking Medicine Technology:Landauer, Inc. Declares Regular Cash Dividend 2Poll: Over One Million Seniors Have Problems with Medicare 'Preferred Pharmacy' Drug Plans 2Poll: Over One Million Seniors Have Problems with Medicare 'Preferred Pharmacy' Drug Plans 3Poll: Over One Million Seniors Have Problems with Medicare 'Preferred Pharmacy' Drug Plans 4TRACE Releases 2012 Global Enforcement Report 2TRACE Releases 2012 Global Enforcement Report 3
... Calif., Aug. 31, 2011 Ambry Genetics today ... aCGH technology.  The Ambry CancerArray™ is a high ... with higher probe density coverage in over 400 ... in these functionally important cancer regions. ...
... CYPRESS, Calif., Aug. 31, 2011 Samsung Medison America ... address a growing demand for its expansive line of ... US sales organization and its management in Samsung Medison ... with over 15 years of medical device sales experience. ...
Cached Medicine Technology:Ambry Genetics Announces Launch of Their CancerArray™ Product and Services Utilizing aCGH Technology 2Samsung Medison America Welcomes Brian Keith as Sales General Manager, USA 2
... Inverness Medical Professional Diagnostics is a ... extensive IFA and DFA test menu that ... and STDs as well as miscellaneous conjugates ... give you a wide assortment of substrates ...
... Our breadth of infectious disease ELISA ... field. With standard assay protocols for faster ... Disease ELISA products provide increased reliability and ... includes antibody detection assays for a wide ...
... Our breadth of infectious disease ELISA products ... With standard assay protocols for faster integration ... ELISA products provide increased reliability and run-to-run ... antibody detection assays for a wide range ...
... ELISA products make us a leader in ... faster integration into the busy laboratory, our ... and run-to-run consistency. Our Infectious Disease ELISA ... wide range of serological assays including ToRCH, ...
Medicine Products: