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Speeding up cancer diagnosis during surgery
Date:9/17/2013

y sensitive technique using lasers to identify the molecules in a tissue sample).

Dr Notingher said: "Our technique does not rely on time consuming and laborious steps of tissue fixation, staining, labelling or sectioning. The beauty is that it can be automated and very objective. To make this new technique suitable for use in the middle of an operation such as Mohs surgery for BCC, we have combined tissue auto-fluorescence, which is quick and good at picking out all the cancer cells (but not at excluding normal tissue) as a first step, followed by Raman scattering, a rather slow but good at separating normal from cancer tissue. By combining these two methods into one technique high accuracy diagnosis of BCC can be obtained in only a few minutes."

Professor Hywel Williams, one of the dermatologists working in the team and Director of the Centre for Evidence Based Dermatology (CEBD) at The University of Nottingham, said: "I am now convinced that this technique is reliable and potentially fast enough to replace conventional methods that determine tumour clearance for basal cell carcinoma removed during Mohs micrographic surgery an advance that will increase the accessibility of Mohs to many more people across the world."


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Contact: Lindsay Brooke
lindsay.brooke@nottingham.ac.uk
44-011-595-15751
University of Nottingham
Source:Eurekalert

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