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Spanish Oncology to establish a new standard treatment on breast cancer at early stages
Date:12/3/2010

ved treatment with taxanos", explains doctor Ana Lluch of Clinico Hospital, Valencia.

"The research launches real figures concerning Breast cancer patients. Treatment benefits were seen in around 70% of patients at early stage and additionally almost 6% patients improved disease-free survival, which means 800 women disease-free per year thanks to this treatment", states doctor Marin. "Up to now, those women were considered low-risk patients and they were not subject of any scientific researches. This concept has been mistaken and caused suboptimal treatments. Thanks to this study we have achieved a new therapeutic tool for a bigger group".

A high-risk of recurrence is considered in the case of women following at least one of the following criteria set by St. Gallen in 1998: patient age of 35 years or older, tumour size greater than 2 cm, negative estrogen-receptor or progesterone-receptor status, tumour histologic grade of 2 or 3.

1060 women participating in the study were randomly assigned to receive TAC or FAC after surgery treated. They received treatment one day every three weeks during six cycles. Scientifics evaluated those criteria: disease-free survival, global survival, treatment security levels and life quality. Results after six years show that adjuvant therapy based on TAC reduce risk of recurrence by 32% and improves disease-free survival. Almost 90% remained disease-free after this period.

For both experts, since now those women will have new alternative therapy. "It is a step towards personalized treatments of this tumour, since the goal is to administrate just those therapies aimed at caused a benefit, avoiding secondary effects. We would thank both women and Spanish Breast Cancer women Federation (FECMA) for all the support. Knowing that one out of eight women will suffer Breast cancer, it is key that all of them are aware of the importance of clinic essays and new researches", explains doctor Miguel Martin. '/>"/>

Contact: Mnica Llorente
mllorente@plannermedia.com
GEICAM (Grupo Espaol de Investigacin en Cncer de Mama)
Source:Eurekalert

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